You Searched For: O-Benzyl-L-tyrosine

Catalog Number: (CAAAJ61715-MC)

Supplier: Thermo Scientific Chemicals

Description: A protein kinase inhibitor

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Catalog Number: (76083-534)

Supplier: Bioss

Description: Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity). Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to the receptor tyrosine kinases EPHB3 (preferred), EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity).

Catalog Number: (76077-894)

Supplier: Bioss

Description: Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation. Stimulation by receptor tyrosine kinases (RTKs) including EGRF, PDGFR, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated receptor, and activation and phosphorylation of downstream substrates. Upon EGFR activation, promotes the phosphorylation of PARD3 to favor epithelial tight junction assembly. Participates in the phosphorylation of specific junctional components such as CTNND1 by stimulating the FYN and FER tyrosine kinases at cell-cell contacts. Upon T-cell stimulation by CXCL12, phosphorylates collapsin response mediator protein 2/DPYSL2 and induces T-cell migration. Participates in CD95L/FASLG signaling pathway and mediates AKT-mediated cell migration. Plays a role in cell cycle progression by phosphorylating the cyclin-dependent kinase 4/CDK4 thus regulating the G1 phase. Also involved in G2/M progression and cytokinesis.

Catalog Number: (89287-174)

Supplier: Genetex

Description: Mouse monoclonal antibody [5F3] to CSK

Supplier: TCI America

Description: CAS Number: 340-05-6
MDL Number: MFCD00004498
Molecular Formula: C8H7F3O
Molecular Weight: 176.14
Purity/Analysis Method: >97.0% (GC)
Form: Clear Liquid
Color: Colorless
Boiling point (°C): 88
Flash Point (°C): 84
Specific Gravity (20/20): 1.30

SDS Certificates

Supplier: TCI America

Description: CAS Number: 150412-81-0
Molecular Formula: C61H64O12
Molecular Weight: 989.17
Purity/Analysis Method: >92.0% (HPLC)
Form: Crystal
Storage Temperature: <0°C

SDS

Catalog Number: (89355-772)

Supplier: Genetex

Description: Rabbit Polyclonal antibody to 14-3-3 epsilon (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide)

Catalog Number: (10475-134)

Supplier: Bioss

Description: This gene is a necessary element in receptor tyrosine kinase pathways, possibly as a tyrosine phosphorylation target. It is involved in regulation of RAF in the MAPK pathway and may also play a role in a MAPK-independent pathway. [provided by RefSeq, Jul 2008].

Catalog Number: (10475-140)

Supplier: Bioss

Description: This gene is a necessary element in receptor tyrosine kinase pathways, possibly as a tyrosine phosphorylation target. It is involved in regulation of RAF in the MAPK pathway and may also play a role in a MAPK-independent pathway. [provided by RefSeq, Jul 2008].

Supplier: Thermo Scientific Chemicals

Description: N-(Methoxymethyl)-N-(trimethylsilylmethyl)benzylamine 94%

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Supplier: Thermo Scientific Chemicals

Description: 3-(3,4-Dihydroxyphenyl)-L-alanine 98+%

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Catalog Number: (10070-010)

Supplier: Prosci

Description: FUNCTION: May play an important role in CKII- and p60c-src-induced signal transduction cascades (By similarity).
CATALYTIC ACTIVITY: Protein tyrosine phosphate + H₂O = protein tyrosine + phosphate.
PTM: Oxidized on Cys-215; the Cys-SOH formed in response to redox signaling reacts with the beta-amido of the following residue to form a 4-amino-3-isothiazolidinone serine cross-link, triggering a conformational change that inhibits substrate binding and activity. The active site can be restored by reduction.

Catalog Number: (10414-984)

Supplier: Bioss

Description: c-Kit is a transmembrane tyrosine kinase encoded by the cKit proto oncogene. c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, and activation. Mutations in c-Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, gastrointestinal stromal tumor, acute myeloid leukemia, Ewing sarcoma and lung cancer. Phosphorylation at tyrosine 721 of c-Kit allows binding and activation of PI3 kinase.

Supplier: Thermo Scientific Chemicals

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Supplier: FUJIFILM IRVINE SCIENTIFIC, INC

Description: Neurotrophin-3 (NT-3) is an important member of the nerve growth factor (NGF) family of proteins. NT-3 promotes the growth, survival, and differentiation of neurons and synapses in the peripheral and central nervous systems. The receptor tyrosine kinase TrkC exclusively binds in high-affinity to NT-3. NT-3 also signals through the receptor tyrosine kinase TrkB, and through the low affinity nerve growth factor receptor (LNGFR).

New Product

Catalog Number: (89283-944)

Supplier: Genetex

Description: Rabbit polyclonal antibody to Tyrosine Hydroxylase (phospho Ser31)