You Searched For: O-Benzyl-L-tyrosine


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Catalog Number: (10416-004)
Supplier: Bioss
Description: The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide linked subunits in a beta-alpha-alpha-beta configuration. The beta subunit (95 kDa) possesses a single transmembrane domain, whereas the alpha subunit (135 kDa) is completely extracellular. The insulin receptor exhibits receptor tyrosine kinase (RTK) activity. RTKs are single pass transmembrane receptors that possess intrinsic cytoplasmic enzymatic activity, catalyzing the transfer of the gamma phosphate of ATP to tyrosine residues in protein substrates. RTKs are essential components of signal transduction pathways that affect cell proliferation, differentiation, migration and metabolism.Included in this large protein family are the insulin receptor and the receptors for growth factors such as epidermal growth factor, fibroblast growth factor and vascular endothelial growth factor. Receptor activation occurs through ligand binding, which facilitates receptor dimerization and autophosphorylation of specific tyrosine residues in the cytoplasmic portion. The interaction of insulin with the alpha subunit of the insulin receptor activates the protein tyrosine kinase of the beta subunit, which then undergoes an autophosphorylation that increases its tyrosine kinase activity. Three adapter proteins, IRS1, IRS2 and Shc, become phosphorylated on tyrosine residues following insulin receptor activation. These three phosphorylated proteins then interact with SH2 domain containing signaling proteins.


Catalog Number: (89348-664)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to SYK (spleen tyrosine kinase)


Catalog Number: (77512-058)
Supplier: AFG Bioscience
Description: Mouse Tie2 (TEK Tyrosine Kinase, Endothelial) ELISA Kit


Catalog Number: (10373-276)
Supplier: Bioss
Description: Neuronal MarkerTyrosine hydroxylase is involved in the conversion of tyrosine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's disease.


Catalog Number: (77517-312)
Supplier: AFG Bioscience
Description: Human MERTK (C-Mer Proto Oncogene Tyrosine Kinase) ELISA Kit


Supplier: Bachem Americas
Description: Sequence: Fmoc-D-Tyr(tBu)-OH

Catalog Number: (77524-898)
Supplier: AFG Bioscience
Description: Mouse PTPLA (Protein Tyrosine Phosphatase Like Protein A) ELISA Kit


Catalog Number: (89355-052)
Supplier: Genetex
Description: Rabbit polyclonal antibody to Brk (Brk protein tyrosine kinase 6)


Supplier: Thermo Scientific Chemicals
Description: Locostatin is a cell permeable, potent inhibitor of Raf kinase inhibitor protein (RKIP)/Raf1 kinase interaction and an inhibitor of cell migration
Supplier: Peprotech
Description: Recombinant Human ROR1, Purity: Greater than 95% by SDS-PAGE gel and HPLC analyses, Source: CHO cells, Synonyms: NTRKR1, receptor-related 1, Tyrosine-protein kinase, transmembrane receptor ROR1, Receptor-tyrosine-kinase-like orphan receptor 1, Size: 100UG

Catalog Number: (77527-684)
Supplier: AFG Bioscience
Description: Rat FYN (Tyrosine-protein kinase Fyn) ELISA Kit


Catalog Number: (77527-782)
Supplier: AFG Bioscience
Description: Rat sFLT (Soluble Fms-Like Tyrosine Kinase Receptor 1) ELISA Kit


Catalog Number: (77042-278)
Supplier: ANTIBODIES.COM LLC
Description: Rabbit polyclonal antibody to Tyrosine Hydroxylase (phospho Ser40) for WB, IHC and ELISA with samples derived from Human, Mouse and Rat.


Supplier: TCI America
Description: CAS Number: 35677-89-5
MDL Number: MFCD00674555
Molecular Formula: C12H13NO4
Molecular Weight: 235.24
Purity/Analysis Method: >98.0% (HPLC,N)
Form: Crystal
Melting point (°C): 129
Specific rotation [a]20/D: -32 deg (C=1, MeOH)

SDS

Catalog Number: (76709-454)
Supplier: AFG Bioscience
Description: Human AXL Receptor Tyrosine kinase (AXL) ELISA Kit


Catalog Number: (10351-656)
Supplier: Bioss
Description: Fibroblast growth factors (FGFs) produce mitogenic and angiogenic effects in target cells by signaling through the cellular surface tyrosine kinase receptors. There are four members of the FGF receptor family: FGFR-1 (flg), FGFR-2 (bek, KGFR), FGFR-3 and FGFR-4. Each receptor contains an extracellular ligand binding domain, a transmembrane region and a cytoplasmic kinase domain (1). Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues (2). Seven tyrosine residues in the cytoplasmic tail of FGFR-1 can be phosphorylated: Tyr463, Tyr583, Tyr585, Tyr653, Tyr654, Tyr730 and Tyr766. Tyrosine 653 and 654 are important for catalytic activity of the activated FGFR and are essential for signaling (3). The other phosphorylated tyrosine residues may provide docking sites for downstream signaling components such as Crk and PLCgamma.


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