You Searched For: O-Benzyl-L-tyrosine

Catalog Number: (10070-592)

Supplier: Prosci

Description: IGF1R(insulin-like growth factor 1 receptor), a transmembrane receptor tyrosine kinase, is widely expressed in many cell types within fetal and postnatal tissues, and in many cell lines. Upon binding to its ligands, IGF-I and IGF-II, receptor autophosphorylation occurs. The triple tyrosine cluster within the kinase domain (Tyr1131, Tyr1135 and Tyr1136) is the earliest major site of autophosphorylation. Phosphorylation of these three tyrosine residues is necessary for kinase activation.Insulin receptors (IRs) share significant similarity with IGF1 receptors in both structure and function,including an equivalent triple tyrosine cluster within the activation loop of the kinase domain (Tyr1146, Tyr1150 and Tyr1151).Tyrosine autophosphorylation of insulin receptor is one of the earliest cellular responses to insulin stimulation. Autophosphorylation begins with phosphorylation of Tyr1146 and either Tyr1150 or Tyr1151. Full kinase activation requires the triple tyrosine phosphorylation.

Catalog Number: (76712-078)

Supplier: AFG Bioscience

Description: Human Protein Tyrosine Kinase 6 (PTK6) ELISA Kit

Catalog Number: (TCM1615-1G)

Supplier: TCI America

Description: CAS Number: 129575-89-9
Molecular Formula: C35H33NO8
Molecular Weight: 595.65
Purity/Analysis Method: >95.0% (HPLC)
Form: Crystal
Storage Temperature: <0°C

SDS

Supplier: Bachem Americas

Description: Sequence: ((RS)-2-Benzyl-3-mercaptopropionyl)-Gly-OH

Catalog Number: (TCG0427-5G)

Supplier: TCI America

Description: Product Categories: Bioscience, Oligopeptides
Other Product Names / Synonyms: Diglycine Benzyl Ester p-Toluenesulfonate, H-Gly-Gly-OBzl.Tos-OH

SDS

Catalog Number: (TCM1609-1G)

Supplier: TCI America

Description: CAS Number: 129575-88-8
MDL Number: MFCD06797139
Molecular Formula: C35H31NO8
Molecular Weight: 593.63
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal
Melting point (°C): 133
Specific rotation [a]20/D: 92 deg (C=1, CHCl3)
Storage Temperature: <0°C

SDS

Catalog Number: (77511-440)

Supplier: AFG Bioscience

Description: Human EPHA2 (Tyrosine protein kinase receptor A2) ELISA Kit

Catalog Number: (77519-904)

Supplier: AFG Bioscience

Description: Human PTPRF (Protein Tyrosine Phosphatase Receptor Type F) ELISA Kit

Catalog Number: (75789-012)

Supplier: Prosci

Description: Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1C is highly expressed in leukocyte cell type. It contains two SH2 domains and one tyrosine-protein phosphatase domain. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. In addition, PTP1C also modulates signaling by tyrosine phosphorylated cell surface receptors.

Catalog Number: (TCS0550-5G)

Supplier: TCI America

Description: CAS Number: 60022-62-0
MDL Number: MFCD00038955
Molecular Formula: C10H13NO3
Molecular Weight: 231.68
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Color: White
Specific rotation [a]20/D: -12 deg (C=1, H2O)

SDS

Supplier: Abcam

Description: Rabbit monoclonal [EP1532Y] to Tyrosine Hydroxylase - BSA and Azide free.

New Product

Catalog Number: (103003-222)

Supplier: Anaspec Inc

Description: Peptide sequence KVEKIGEGTYGVVYK is derived from the amino acid residues CDC26-20. It is considered to be a generic substrate for various TPKs.
Sequence:KVEKIGEGTYGVVYK
MW:1669.9 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: TCI America

Description: Benzyl (3-Fluoro-4-morpholinophenyl)carbamate, Purity: >98.0%(HPLC)(N), Cas no. 168828-81-7, Molecular formula: C18H19FN2O3, Form: Crystal - Powder, Synonyms: (3-Fluoro-4-morpholinophenyl)carbamic Acid Benzyl Ester, Size: 25G

SDS

Catalog Number: (89141-426)

Supplier: Enzo Life Sciences

Description: The enzymatic conversion of arginine to citrulline by nitric oxide synthase (NO Synthase) leads to the formation of nitric oxide (NO). Peroxynitrite is formed following reaction of NO with superoxide, producing a potent oxidant that reacts with a variety of biological molecules, including tyrosine residues in proteins. Tyrosine nitration can inactivate enzymes and receptors that depend on tyrosine residues for their activity. Nitration prevents phosphorylation of tyrosine residues important for signal transduction.

Catalog Number: (10413-416)

Supplier: Bioss

Description: Fibroblast growth factors (FGFs) produce mitogenic and angiogenic effects in target cells by signaling through the cellular surface tyrosine kinase receptors. There are four members of the FGF receptor family: FGFR-1 (flg), FGFR-2 (bek, KGFR), FGFR-3 and FGFR-4. Each receptor contains an extracellular ligand binding domain, a transmembrane region and a cytoplasmic kinase domain (1). Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues (2). Seven tyrosine residues in the cytoplasmic tail of FGFR-1 can be phosphorylated: Tyr463, Tyr583, Tyr585, Tyr653, Tyr654, Tyr730 and Tyr766. Tyrosine 653 and 654 are important for catalytic activity of the activated FGFR and are essential for signaling (3). The other phosphorylated tyrosine residues may provide docking sites for downstream signaling components such as Crk and PLCgamma.

Catalog Number: (10413-436)

Supplier: Bioss

Description: Fibroblast growth factors (FGFs) produce mitogenic and angiogenic effects in target cells by signaling through the cellular surface tyrosine kinase receptors. There are four members of the FGF receptor family: FGFR-1 (flg), FGFR-2 (bek, KGFR), FGFR-3 and FGFR-4. Each receptor contains an extracellular ligand binding domain, a transmembrane region and a cytoplasmic kinase domain (1). Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues (2). Seven tyrosine residues in the cytoplasmic tail of FGFR-1 can be phosphorylated: Tyr463, Tyr583, Tyr585, Tyr653, Tyr654, Tyr730 and Tyr766. Tyrosine 653 and 654 are important for catalytic activity of the activated FGFR and are essential for signaling (3). The other phosphorylated tyrosine residues may provide docking sites for downstream signaling components such as Crk and PLCgamma.