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Catalog Number: (10665-630)
Supplier: Bioss
Description: Members of the EF-CBP (N-terminal EF-hand calcium binding protein)/NECAB (neuronal calcium-binding protein) family participate in neuronal calcium signaling. EF-CBP2, also known as NECAB2 (N-terminal EF-hand calcium binding protein 2), neuronal calcium-binding protein 2 or synaptotagmin-interacting protein 2 (Stip-2), is a 386 amino acid cytoplasmic protein that contains one antibiotic biosynthesis monooxygenase (ABM) domain and two EF-hand domains. Expressed in brain, EF-CBP2 is suggested to bind metabotropic glutamate receptor 5 (mGluR-5) in a calcium-regulated manner. The gene encoding EF-CBP2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.


Catalog Number: (10751-260)
Supplier: Prosci
Description: MYOZAP Antibody: MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein. It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.


Supplier: TCI America
Description: CAS Number: 4836-13-9
MDL Number: MFCD00010115
Molecular Formula: C16H17N3O5
Molecular Weight: 331.33
Purity/Analysis Method: >98.0% (N)
Form: Crystal
Melting point (°C): 207
Specific rotation [a]20/D: 90 deg (C=0.25, MeOH)

SDS

Catalog Number: (CAAAJ65402-03)
Supplier: Thermo Scientific Chemicals
Description: Powder

Catalog Number: (TCB2720-25G)
Supplier: TCI America
Description: CAS Number: 63242-14-8
Molecular Formula: C19H13BrO
Molecular Weight: 337.22
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Melting point (°C): 157

SDS


Supplier: TCI America
Description: [for Determination of Chymotrypsin]
CAS Number: 15873-25-3
MDL Number: MFCD00021607
Molecular Formula: C26H21NO3
Molecular Weight: 395.46
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal
Melting point (°C): 158

SDS

Supplier: TCI America
Description: CAS Number: 5354-94-9
MDL Number: MFCD00037850
Molecular Formula: C13H13N3O3
Molecular Weight: 259.27
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Specific rotation [a]20/D: -47 deg (C=2, 0.5mol/L HCl)
Catalog Number: (10075-672)
Supplier: Prosci
Description: The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death. Overexpression of the NR2B subunit of the receptor has been associated with increases in learning and memory while aged, memory impaired animals have deficiencies in NR2B expression. Tyr1472 on NR2B is phosphorylated and this may lead to the increased expression of the NMDAR at the synapse that plays a role in synaptic plasticity.


Catalog Number: (10087-524)
Supplier: Proteintech
Description: GGCX(Gamma-glutamyl carboxylase) is also named as GC and belongs to the vitamin K-dependent gamma-carboxylase family. This 94 kDa (including all modifications, such as the five N-linked glycosylations), is a 5-pass transmembrane protein and a key regulator of blood coagulation. It mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. Defects in GGCX are a cause of combined deficiency of vitamin K-dependent clotting factors type 1 (VKCFD1) and pseudoxanthoma elasticum-like disorder with multiple coagulation factor deficiency (PXEL-MCFD).


Catalog Number: (10665-636)
Supplier: Bioss
Description: Members of the EF-CBP (N-terminal EF-hand calcium binding protein)/NECAB (neuronal calcium-binding protein) family participate in neuronal calcium signaling. EF-CBP2, also known as NECAB2 (N-terminal EF-hand calcium binding protein 2), neuronal calcium-binding protein 2 or synaptotagmin-interacting protein 2 (Stip-2), is a 386 amino acid cytoplasmic protein that contains one antibiotic biosynthesis monooxygenase (ABM) domain and two EF-hand domains. Expressed in brain, EF-CBP2 is suggested to bind metabotropic glutamate receptor 5 (mGluR-5) in a calcium-regulated manner. The gene encoding EF-CBP2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.


Catalog Number: (10665-632)
Supplier: Bioss
Description: Members of the EF-CBP (N-terminal EF-hand calcium binding protein)/NECAB (neuronal calcium-binding protein) family participate in neuronal calcium signaling. EF-CBP2, also known as NECAB2 (N-terminal EF-hand calcium binding protein 2), neuronal calcium-binding protein 2 or synaptotagmin-interacting protein 2 (Stip-2), is a 386 amino acid cytoplasmic protein that contains one antibiotic biosynthesis monooxygenase (ABM) domain and two EF-hand domains. Expressed in brain, EF-CBP2 is suggested to bind metabotropic glutamate receptor 5 (mGluR-5) in a calcium-regulated manner. The gene encoding EF-CBP2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.


Catalog Number: (76109-692)
Supplier: Bioss
Description: Members of the EF-CBP (N-terminal EF-hand calcium binding protein)/NECAB (neuronal calcium-binding protein) family participate in neuronal calcium signaling. EF-CBP2, also known as NECAB2 (N-terminal EF-hand calcium binding protein 2), neuronal calcium-binding protein 2 or synaptotagmin-interacting protein 2 (Stip-2), is a 386 amino acid cytoplasmic protein that contains one antibiotic biosynthesis monooxygenase (ABM) domain and two EF-hand domains. Expressed in brain, EF-CBP2 is suggested to bind metabotropic glutamate receptor 5 (mGluR-5) in a calcium-regulated manner. The gene encoding EF-CBP2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.


Catalog Number: (TCM2013-1G)
Supplier: TCI America
Description: CAS Number: 6748-91-0
MDL Number: MFCD02167693
Molecular Formula: C28H26O8
Molecular Weight: 490.51
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal
Melting point (°C): 154
Specific rotation [a]20/D: 94 deg (C=1, CHCl3)

SDS


Supplier: Bachem Americas
Description: Sequence: Bz-DL-Arg-pNA · HCl

Catalog Number: (CAAAJ64064-03)
Supplier: Thermo Scientific Chemicals
Description: Powder

Catalog Number: (E-1530.0025BA)
Supplier: Bachem Americas
Description: Sequence: Bz-Tyr-OEt


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