You Searched For: 3-Iodoanisole

Supplier: Peprotech

Description: GDNF is a disulfide-linked, homodimeric neurotrophic factor structurally related to Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. GDNF signals through a multicomponent receptor system, composed of a RET and one of the four GFRalpha (alpha1-alpha4) receptors. GDNF specifically promotes dopamine uptake and survival, and morphological differentiation of midbrain neurons. Using a Parkinson's disease mouse model, GDNF has been shown to improve conditions such as bradykinesia, rigidity, and postural instability. The functional rat GDNF ligand is a disulfide-linked homodimer consisting of two 15 kDa polypeptide chains called monomers. Each monomer contains seven conserved cysteine residues, including Cys-101, which is used for inter-chain disulfide bridging, and others that are involved in the intramolecular ring formation known as the cysteine-knot configuration. The calculated molecular weight of Recombinant Rat GDNF is 30.0 kDa.

Catalog Number: (CAJT4043-1)

Supplier: AVANTOR PERFORMANCE MATERIAL LLC

Description: Glycerol, anhydrous, Ultrapure Bioreagent, for enzyme stabilisation, freezing and electrophoresis buffers.

Certificates

Supplier: CHEM SCIENCE INC CA

Description: With identical vertical side joints.

Catalog Number: (36522-008)

Supplier: LX Microscopes by UNITRON

Description: Vertical lamp bracket for incandescent, fluorescent, and combination lamps (36520-046, -239). Vertical bracket permanently attaches with screws to any wall or partition to support lamp fixture vertically. Deep throat ensures stability. Supplied without screws.

Supplier: Peprotech

Description: Members of the Hedgehog (Hh) family are highly conserved proteins that are widely represented throughout the animal kingdom. The three known mammalian Hh proteins, Sonic (Shh), Desert (Dhh) and Indian (Ihh), are structurally related, and share a high degree of amino acid sequence identity (e.g. Shh and Ihh are 93% identical). The biologically active form of each Hh molecule is obtained by autocatalytic cleavage of their precursor proteins, and each corresponds to approximately one half of the N-terminal portion of the precursor molecule. Although Hh proteins have unique expression patterns and distinct biological roles within their respective regions of secretion, they use the same signaling pathway and can be substituted for one another in experimental systems. Recombinant Murine Sonic Hedgehog (Shh) is a 20.0 kDa protein consisting of 176 amino acid residues, including an N-terminal Ile-Val-Ile sequence substituted for the naturally occurring, chemically modified Cys residue.

Supplier: VWR

Description: TBE is optimized for DNA electrophoresis techniques using both acrylamide and agarose.A concentrated (10X), pH adjusted solution of Ultra Pure Grade Tris Buffer, ACS Grade Boric Acid & EDTA which when reconstituted to a working (1X) Solution concentration, contains 0.089M Tris, 0.089M Borate & 0.002M EDTA.

SDS Certificates

Supplier: VWR

Description: Commonly used to denature nucleic acids for electrophoresis and to study the secondary and tertiary structure of proteins. Effective for maintaining DNA in a highly denatured state during sequencing protocols, urea is also useful for accelerating the acti

SDS Certificates

Supplier: Ace Glass

Description: Two neck, one center and one vertical side neck, round bottom flask with standard taper joints

Supplier: VWR International

Description: Great for glassware setups in small laboratories or where space is limited.

Catalog Number: (100497-010)

Supplier: Electron Microscopy Sciences

Description: Use for Edge Polishing, Model 155D, 2" (50mm) Diameter Mounting Block, Vertically Mounted Samples; Star Pattern, Reversible, 6-position for 12mm Diameter Rod or 10mm Cube (Max 20mm S

Supplier: MAZE ENGINEERS

Description: The vertical tank array is used for anxiety experiments for Zebrafish.

Catalog Number: (100493-296)

Supplier: Electron Microscopy Sciences

Description: The stainless steel tray has grooves that hold 76 x 26 mm (3 x 1") microscope slides vertically. Accommodates up to 60 slides.

Catalog Number: (10836-726)

Supplier: VWR

Description: Loading Dye Base, 50X is used for custom loading buffer preparation.

SDS Certificates

Supplier: VWR International

Description: Extra-large lab frames offer the greatest versatility for your most demanding setups.

Supplier: VWR

Description: Commonly used to denature nucleic acids for electrophoresis and to study the secondary and tertiary structure of proteins. Effective for maintaining DNA in a highly denatured state during sequencing protocols, urea is also useful for accelerating the activity of Proteinase K digestions. Effectively denatures RNA. For use in nucleic electrophoresis applications.

SDS Certificates

Supplier: Peprotech

Description: GDNF is a disulfide-linked, homodimeric neurotrophic factor structurally related to Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. GDNF signals through a multicomponent receptor system, composed of a RET and one of the four GFRα (α1-α4) receptors. GDNF specifically promotes dopamine uptake and survival, and morphological differentiation of midbrain neurons. Using a Parkinson’s disease mouse model, GDNF has been shown to improve conditions such as bradykinesia, rigidity, and postural instability. The functional murine GDNF ligand is a disulfide-linked homodimer consisting of two 15.1 kDa polypeptide chains called monomers. Each monomer contains seven conserved cysteine residues, including Cys-101, which is used for inter-chain disulfide bridging, and others that are involved in the intramolecular ring formation known as the cysteine knot configuration. The calculated molecular weight of Recombinant Murine GDNF is 30.2 kDa.