You Searched For: Methyl-alpha-D-galactopyranoside+monohydrate

Catalog Number: (10082-812)

Supplier: Proteintech

Description: There are five tubulins in human cells: alpha, beta, gamma, delta, and epsilon. Tubulins are conserved across species. They form heterodimers, which multimerize to form a microtubule filament. An alpha and beta tubulin heterodimer is the basic structural unit of microtubules. The heterodimer does not come apart, once formed. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha, beta, and gamma tubulins have all been used as loading controls. Tubulin expression may vary according to resistance to antimicrobial and antimitotic drugs. This antibody recognize Tubulin Alpha only.

Catalog Number: (75791-028)

Supplier: Prosci

Description: Tumor Necrosis Factor- alpha (TNF- alpha) is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells following stimulation by bacterial LPS. Cells expressing CD4 secrete TNF- alpha while cells that express CD8 secrete little or no TNF- alpha. Synthesis of TNF- alpha can be induced by many different stimuli including interferons, IL2, and GM-CSF. The clinical use of the potent anti-tumor activity of TNF- alpha has been limited by the proinflammatory side effects such as fever, dose-limiting hypotension, hepatotoxicity, intravascular thrombosis, and hemorrhage. Designing clinically applicable TNF- alpha mutants with low systemic toxicity has been of intense pharmacological interest. Human TNF- alpha that binds to murine TNF-R55 but not murine TNF-R7, exhibits retained anti-tumor activity and reduced systemic toxicity in mice compared with murine TNF- alpha, which binds to both murine TNF receptors. Based on these results, many TNF- alpha mutants that selectively bind to TNF-R55 have been designed. These mutants displayed cytotoxic activities on tumor cell lines in vitro and have exhibited lower systemic toxicity in vivo. Recombinant Human TNF- alpha High Active Mutant differs from the wild-type by amino acid subsitution of amino acids 1-7 with Arg8, Lys9, Arg10 and Phe157. This mutant form has been shown to have increased activity with less inflammatory side effects in vivo.

Catalog Number: (102878-420)

Supplier: R&D Systems

Description: The Recombinant Human TNF-alpha, Animal-Free Protein from R&D Systems is derived from E. coli. The Recombinant Human TNF-alpha, Animal-Free Protein has been validated for the following applications: Bioactivity.

Catalog Number: (89316-532)

Supplier: Genetex

Description: Rabbit polyclonal antibody to GRO alpha (chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha))

Catalog Number: (ABCA_AB131468-100U)

Supplier: Abcam

Description: Rabbit polyclonal to CaMKII alpha.

New Product

Catalog Number: (ABCA_AB5162-100UL)

Supplier: Abcam

Description: Rabbit polyclonal to LAP2 alpha.

New Product

Catalog Number: (ABCA_AB77256-100UG)

Supplier: Abcam

Description: Goat polyclonal to HP1 alpha.

New Product

Catalog Number: (76715-318)

Supplier: AFG Bioscience

Description: Human Alpha-Granular Membrane Protein(GMP-140) ELISA Kit

Catalog Number: (103368-070)

Supplier: Novus Biologicals

Description: The HIF-1 alpha Antibody (H1alpha 67-7) [Alexa Fluor« 488] from Novus Biologicals is a mouse monoclonal antibody to HIF-1 alpha. This antibody reacts with human, monkey. The HIF-1 alpha Antibody (H1alpha 67-7) [Alexa Fluor« 488] has been validated for the following applications: Western Blot.

Catalog Number: (89335-454)

Supplier: Genetex

Description: Rabbit Polyclonal antibody to Hsp90 alpha (heat shock protein HSP 90-alpha)

Catalog Number: (10069-118)

Supplier: Prosci

Description: Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform beta-1B interferes with isoform beta-1A resulting in a dominant negative effect on cell adhesion and migration (in vitro). In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. When associated with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and GNB2L1/RACK1, serves as a platform for SRC activation or inactivation. Plays a mechanistic adhesive role during telophase, required for the successful completion of cytokinesis

Catalog Number: (89319-870)

Supplier: Genetex

Description: Rabbit Polyclonal antibody to Casein Kinase 2 alpha (casein kinase 2, alpha 1 polypeptide)

Catalog Number: (89320-968)

Supplier: Genetex

Description: Rabbit Polyclonal antibody to alpha amylase 2B (pancreatic) (amylase, alpha 2B (pancreatic))

Supplier: Thermo Scientific Chemicals

Description: α,α,α-Trifluoro-p-toluonitrile 98%

Certificates

Catalog Number: (76118-880)

Supplier: Bioss

Description: Produced by macrophages, IFN alpha have mainly antiviral activities.

Catalog Number: (89278-564)

Supplier: Genetex

Description: Goat Polyclonal antibody to Human IgA Alpha chain