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Image Unavailable-10781-870

Mouse Recombinant GDNF (from E. coli)

Catalog Number: (10781-870)
Supplier: Peprotech
Description: GDNF is a disulfide-linked, homodimeric neurotrophic factor structurally related to Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. GDNF signals through a multicomponent receptor system, composed of a RET and one of the four GFRα (α1-α4) receptors. GDNF specifically promotes dopamine uptake and survival, and morphological differentiation of midbrain neurons. Using a Parkinson’s disease mouse model, GDNF has been shown to improve conditions such as bradykinesia, rigidity, and postural instability. The functional murine GDNF ligand is a disulfide-linked homodimer consisting of two 15.1 kDa polypeptide chains called monomers. Each monomer contains seven conserved cysteine residues, including Cys-101, which is used for inter-chain disulfide bridging, and others that are involved in the intramolecular ring formation known as the cysteine knot configuration. The calculated molecular weight of Recombinant Murine GDNF is 30.2 kDa.
Image Unavailable-10339-898

Anti-IL13RA2 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10339-898)
Supplier: Bioss
Description: Binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4).
Image Unavailable-10339-904

Anti-IL13RA2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10339-904)
Supplier: Bioss
Description: Binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4).
Image Unavailable-CAAAH56533-06

3,4-Ethylenedioxythiophene 97%

Supplier: Thermo Scientific Chemicals
Description: Often used as a monomer to synthesize the conductive polymer PEDT

Certificates

Image Unavailable-CAAA44151-30

Ethylene glycol dimethacrylate (ethylene dimethacrylate) 98% stabilized

Supplier: Thermo Scientific Chemicals
Description: Applications: Crosslinking monomer

Certificates

Product Image-10095-848

Anti-TFR1 Rabbit Polyclonal Antibody

Catalog Number: (10095-848)
Supplier: Proteintech
Description: CD71, also known as transferrin receptor protein 1 (TfR1), is a transmembrane glycoprotein composed of two disulfide-linked monomers, each of 90 kDa molecular weight. Each monomer binds one holo-transferrin molecule creating an iron-Tf-TfR complex which enters the cell by endocytosis. CD71 is present on actively proliferating cells and is essential for iron transport into proliferating cells.
Product Image-97000-588

VWR® Two-Sided Disposable Plastic Cuvettes

Supplier: VWR International
Description: Cuvettes are constructed of high-quality polymethyl methacrylate (PMMA or "acrylic") or polystyrene (PS), and provide accurate, reliable results.

Certificates Product available on GSA Advantage®

Product Image-10032-086

VWR® Acrylic Dispensing Bins

Supplier: VWR International
Description: The flip top lids on the top and on the front of these general use dispensing bins will keep your supplies clean and dust-free.

Product Image-10110-064

Anti-PFN1 Rabbit Polyclonal Antibody

Catalog Number: (10110-064)
Supplier: Prosci
Description: PFN1 is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome.The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Image Unavailable-CAPIPA5-18605

Anti-GSN Goat Polyclonal Antibody

Catalog Number: (CAPIPA5-18605)
Supplier: Thermo Scientific
Description: This antibody is predicted to react with canine, mouse and rat based on sequence homology. The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type . Multiple transcript variants encoding several different isoforms have been found for this gene.
Image Unavailable-CA8.00835.0500

2-Ethylhexyl acrylate stabilized for synthesis, Sigma-Aldrich®

Supplier: MilliporeSigma
Description: 2-Ethylhexyl acrylate(stabilised with hydroquinone monomethyl ether), CAS number:103-11-7, Synonyms:Acrylic acid 2-ethylhexyl ester, Application:for synthesis

SDS Certificates

Image Unavailable-10781-424

Rat Recombinant GDNF (from E. coli)

Supplier: Peprotech
Description: GDNF is a disulfide-linked, homodimeric neurotrophic factor structurally related to Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. GDNF signals through a multicomponent receptor system, composed of a RET and one of the four GFRα (α1-α4) receptors. GDNF specifically promotes dopamine uptake and survival, and morphological differentiation of midbrain neurons. Using a Parkinson’s disease mouse model, GDNF has been shown to improve conditions such as bradykinesia, rigidity, and postural instability. The functional rat GDNF ligand is a disulfide-linked homodimer consisting of two 15 kDa polypeptide chains called monomers. Each monomer contains seven conserved cysteine residues, including Cys-101, which is used for inter-chain disulfide bridging, and others that are involved in the intramolecular ring formation known as the cysteine knot configuration. The calculated molecular weight of Recombinant Rat GDNF is 30.0 kDa.

Image Unavailable-10781-224

Human Recombinant GDNF (from E. coli)

Supplier: Peprotech
Description: GDNF is a disulfide-linked, homodimeric neurotrophic factor structurally related to Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. GDNF signals through a multicomponent receptor system, composed of a RET and one of the four GFRα (α1-α4) receptors. GDNF specifically promotes dopamine uptake and survival, and morphological differentiation of midbrain neurons. Using a Parkinson’s disease mouse model, GDNF has been shown to improve conditions such as bradykinesia, rigidity, and postural instability. The functional human GDNF ligand is a disulfide-linked homodimer consisting of two 15 kDa polypeptide chains called monomers. Each monomer contains seven conserved cysteine residues, including Cys-101, which is used for inter-chain disulfide bridging, and others that are involved in the intramolecular ring formation known as the cysteine knot configuration. The calculated molecular weight of Recombinant Human GDNF is 30.4 kDa.

Image Unavailable-CAAAAB22642-03

2-Mercaptothiophene 97% (as monomer) contains dimer

Supplier: Thermo Scientific Chemicals
Description: 2-Mercaptothiophene 97% (as monomer) contains dimer

Certificates

Image Unavailable-TCM1531-5G

4-Methacryloyloxy-2,2,6,6-tetramethylpiperidine-1-oxyl ≥98.0% (by GC, titration analysis) radical_free

Supplier: TCI America
Description: CAS Number: 15051-46-4
MDL Number: MFCD17677357
Molecular Formula: C13H22NO3
Molecular Weight: 240.32
Purity/Analysis Method: >98.0% (GC,T)
Form: Crystal
Melting point (°C): 89
Storage Temperature: 0-10°C

SDS

Image Unavailable-10781-232

Human Recombinant Neurturin (from E. coli)

Supplier: Peprotech
Description: Neurturin is a disulfide-linked homodimer neurotrophic factor structurally related to GDNF, artemin, and persephin. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Neurturin signals through a multicomponent receptor system, composed of RET and one of four GFRα (α1-α4) receptors. Neurturin promotes the development and survival of sympathetic and sensory neurons by signaling through a receptor system composed of RET and GFRα2. The functional form of human neurturin is a disulfide-linked homodimer, of two 11.8 kDa polypeptide monomers (204 total amino acid residues). Each monomer contains seven conserved cysteine residues, one of which (Cys 69) is used for inter-chain disulfide bridging, and the others are involved in the intramolecular ring formation known as the cysteine knot configuration.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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