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Image Unavailable-10414-104

Anti-HSF1 Rabbit Polyclonal Antibody

Catalog Number: (10414-104)
Supplier: Bioss
Description: Two HSFs have been identified in human cells, HSF 1 and HSF 2, which bind to the same HSEs and have 38% sequence identity. These factors are activated by distinct stimuli, HSF 1 is responsive to classical stress signals such as heat, heavy metals and oxidative reagents, whereas HSF 2 is activated during hemin-mediated differentiation of human erythroleukemia cells.HSF 1 exists constitutively in the cytoplasm and the nucleus of unstressed cells as a monomer which lacks DNA binding activity. Through an unknown signal generated during stress, HSF 1 becomes activated to a nuclear localized, trimeric state which binds to DNA. The phosphorylation of HSF 1 is necessary for maximal transcription of heat shock genes.
Image Unavailable-76098-524

Anti-S100B Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76098-524)
Supplier: Bioss
Description: Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Image Unavailable-76082-264

Anti-PDGF Receptor beta Tyr1021 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76082-264)
Supplier: Bioss
Description: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
Image Unavailable-10779-696

Human Recombinant IL-16 (from E. coli)

Catalog Number: (10779-696)
Supplier: Peprotech
Description: IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells, CD4+ monocytes, and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4 + T cells. Human and murine IL-16 show significant cross-species reactivity. Recombinant Human IL-16 is a 12.4 kDa protein consisting of 121 amino acid residues.
Image Unavailable-10491-892

Anti-gamma crystallin S Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10491-892)
Supplier: Bioss
Description: Crystallins are water soluble structural proteins found in the vertebrate eye. Mammalian crystallins are classified in three forms, designated α, β and γ. Crystallins, as the principal components of the lens, function to increase the refractive index of the eye during accommodation by forming high-molecular weight aggregates which maintain transparency. γS-crystallin (Gamma-crystallin S), also known as Beta-crystallin S, is a 178 amino acid protein that exists as a monomer which does not aggregate. γS-crystallin contains a two-domain beta structure and belongs to the beta/gamma-crystallin gene family mapping to human chromosome 3. γS-crystallin has been linked to congenital cataract development, a disorder signified by increasing levels of lens opacity.
Product Image-10018-554

Polyester (B-855), Metal Detectable Polyester (B-854) Labels, type B30, ToughWash®, Brady

Supplier: Brady Worldwide
Description: ToughWash® material polyester film with acrylic adhesive is a strong, print-on-demand label specially formulated for the Food and Beverage processing industry.

Image Unavailable-10491-888

Anti-gamma crystallin S Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10491-888)
Supplier: Bioss
Description: Crystallins are water soluble structural proteins found in the vertebrate eye. Mammalian crystallins are classified in three forms, designated α, β and γ. Crystallins, as the principal components of the lens, function to increase the refractive index of the eye during accommodation by forming high-molecular weight aggregates which maintain transparency. γS-crystallin (Gamma-crystallin S), also known as Beta-crystallin S, is a 178 amino acid protein that exists as a monomer which does not aggregate. γS-crystallin contains a two-domain beta structure and belongs to the beta/gamma-crystallin gene family mapping to human chromosome 3. γS-crystallin has been linked to congenital cataract development, a disorder signified by increasing levels of lens opacity.
Image Unavailable-10491-886

Anti-gamma crystallin S Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10491-886)
Supplier: Bioss
Description: Crystallins are water soluble structural proteins found in the vertebrate eye. Mammalian crystallins are classified in three forms, designated α, β and γ. Crystallins, as the principal components of the lens, function to increase the refractive index of the eye during accommodation by forming high-molecular weight aggregates which maintain transparency. γS-crystallin (Gamma-crystallin S), also known as Beta-crystallin S, is a 178 amino acid protein that exists as a monomer which does not aggregate. γS-crystallin contains a two-domain beta structure and belongs to the beta/gamma-crystallin gene family mapping to human chromosome 3. γS-crystallin has been linked to congenital cataract development, a disorder signified by increasing levels of lens opacity.
Product Image-100493-150

Nitrogen Purge Cabinet, Electron Microscopy Sciences

Catalog Number: (100493-150)
Supplier: Electron Microscopy Sciences
Description: Acrylic, ethylene propylene, and Type 316 stainless steel welded parts

Minority or Woman-Owned Business Enterprise


Image Unavailable-CAAAAL06324-14

4-Ethoxycinnamic acid predominantly trans ≥98%

Supplier: Thermo Scientific Chemicals
Description: 4-Ethoxycinnamic acid predominantly trans ≥98%

Product Image-89133-046

Miscellaneous Dissolution Accessories, Quality Lab Accessories

Supplier: QLA
Description: Everclear Water Bath Preservative is a crystalline formula offered in premeasured vials for use with dissolution water baths.Use with DEIONIZED water

Product Image-16002-788

Flow Meter, Nitrogen, with Metering Valve, Chemglass

Supplier: Chemglass
Description: Precision machined clear acrylic Nitrogen flowmeter with brass metering valve and Buna-N seals for use with Chemglass process reactors.

Small Business Enterprise

Product Image-89408-346

Accessories for Low Profile Roller, IBI Scientific

Supplier: IBI Scientific
Description: For Rollers Made Of 3/8 Inch Acrylic With Clear Anodized Aluminum 1 Inch Diameter Legs - 10 Inch High

Product Image-470219-476

Optical Refraction Components

Supplier: Wards
Description: These Optical Refraction Components are made from imported optical glass or acrylic with optically worked surfaces.

Product Image-76670-366

Automated Repeated Acquisition and Performance Chambers

Supplier: MAZE ENGINEERS
Description: The repeated acquisition and performance chamber (RAPC) is an acrylic device with a start and end goal box. Correct entry to the final destination/goal box allows access to a reward determined by the experimenter.

Image Unavailable-10491-884

Anti-gamma crystallin S Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10491-884)
Supplier: Bioss
Description: Crystallins are water soluble structural proteins found in the vertebrate eye. Mammalian crystallins are classified in three forms, designated α, β and γ. Crystallins, as the principal components of the lens, function to increase the refractive index of the eye during accommodation by forming high-molecular weight aggregates which maintain transparency. γS-crystallin (Gamma-crystallin S), also known as Beta-crystallin S, is a 178 amino acid protein that exists as a monomer which does not aggregate. γS-crystallin contains a two-domain beta structure and belongs to the beta/gamma-crystallin gene family mapping to human chromosome 3. γS-crystallin has been linked to congenital cataract development, a disorder signified by increasing levels of lens opacity.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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