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Rat Recombinant GDNF (from E. coli)

Catalog Number: (76303-888)
Supplier: Peprotech
Description: GDNF is a disulfide-linked, homodimeric neurotrophic factor structurally related to Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. GDNF signals through a multicomponent receptor system, composed of a RET and one of the four GFRalpha (alpha1-alpha4) receptors. GDNF specifically promotes dopamine uptake and survival, and morphological differentiation of midbrain neurons. Using a Parkinson's disease mouse model, GDNF has been shown to improve conditions such as bradykinesia, rigidity, and postural instability. The functional rat GDNF ligand is a disulfide-linked homodimer consisting of two 15 kDa polypeptide chains called monomers. Each monomer contains seven conserved cysteine residues, including Cys-101, which is used for inter-chain disulfide bridging, and others that are involved in the intramolecular ring formation known as the cysteine-knot configuration. The calculated molecular weight of Recombinant Rat GDNF is 30.0 kDa.
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3-(1-Naphthyl)acrylic acid 98%

Supplier: Thermo Scientific Chemicals
Description: 3-(1-Naphthyl)acrylic acid 98%

Certificates

Image Unavailable-75999-672

Rat Recombinant GDNF (from E. coli)

Supplier: Peprotech
Description: GDNF is a disulfide-linked, homodimeric neurotrophic factor structurally related to Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. GDNF signals through a multicomponent receptor system, composed of a RET and one of the four GFRalpha (alpha1-alpha4) receptors. GDNF specifically promotes dopamine uptake and survival, and morphological differentiation of midbrain neurons. Using a Parkinson's disease mouse model, GDNF has been shown to improve conditions such as bradykinesia, rigidity, and postural instability. The functional rat GDNF ligand is a disulfide-linked homodimer consisting of two 15 kDa polypeptide chains called monomers. Each monomer contains seven conserved cysteine residues, including Cys-101, which is used for inter-chain disulfide bridging, and others that are involved in the intramolecular ring formation known as the cysteine-knot configuration. The calculated molecular weight of Recombinant Rat GDNF is 30.0 kDa.

Image Unavailable-10771-112

Mouse Recombinant GDNF (from E. coli)

Supplier: Peprotech
Description: GDNF is a disulfide-linked, homodimeric neurotrophic factor structurally related to Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. GDNF signals through a multicomponent receptor system, composed of a RET and one of the four GFRα (α1-α4) receptors. GDNF specifically promotes dopamine uptake and survival, and morphological differentiation of midbrain neurons. Using a Parkinson’s disease mouse model, GDNF has been shown to improve conditions such as bradykinesia, rigidity, and postural instability. The functional murine GDNF ligand is a disulfide-linked homodimer consisting of two 15.1 kDa polypeptide chains called monomers. Each monomer contains seven conserved cysteine residues, including Cys-101, which is used for inter-chain disulfide bridging, and others that are involved in the intramolecular ring formation known as the cysteine knot configuration. The calculated molecular weight of Recombinant Murine GDNF is 30.2 kDa.

Image Unavailable-CAPIPA526612

Anti-ACSS2 Rabbit Polyclonal Antibody

Catalog Number: (CAPIPA526612)
Supplier: Thermo Scientific
Description: ACSS2 is a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP.
Product Image-10102-064

Anti-RORB Rabbit Polyclonal Antibody

Catalog Number: (10102-064)
Supplier: Prosci
Description: RORB is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation. The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Product Image-97064-542

VWR® Acrylamide and Bis-Acrylamide

Catalog Number: (97064-542)
Supplier: VWR
Description: An extensive line of acrylamide and bis-acrylamide pre-weighed powder blends, premixed stock solutions and ready-to-use solutions for customized polyacrylamide gel electrophoresis of proteins and PAGE of nucleic acids. Ultra-pure (>99.9%) acrylamide and bis-acrylamide powders provide the flexibility to prepare solutions having concentrations and ratios for all electrophoresis applications. Liquid blends minimize the handling of neurotoxic acrylamide.

SDS Certificates


Image Unavailable-CA501816-BL

Anti-IL-12 p40 Mouse Monoclonal Antibody (Alexa Fluor® 488) [clone: C11.5]

Catalog Number: (CA501816-BL)
Supplier: Biolegend
Description: Alexa Fluor® 488 anti-human IL-12/IL-23 p40 [C11.5]; Isotype: Mouse IgG1, κ; Reactivity: Human, IL-12/IL-23 p40 subunit (monomer, homodimer and heterodimer IL-12 p35/p40 or IL-23 p19/p40); Apps: ICFC; Size: 100 tests
Image Unavailable-TCH1168-250G

Hexadecyl acrylate ≥90.0% stabilized

Supplier: TCI America
Description: (stabilized with MEHQ)
CAS Number: 13402-02-3
Molecular Formula: C19H36O2
Molecular Weight: 296.50
Purity/Analysis Method: >90.0% (GC)
Form: Clear Liquid
Flash Point (°C): 178
Freezing point (°C): 17
Specific Gravity (20/20): 0.87

SDS Certificates

Image Unavailable-77439-704

Anti-IL-13Ra2 Rabbit Polyclonal Antibody

Catalog Number: (77439-704)
Supplier: Bioss
Description: Binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4).
Image Unavailable-CAAAB22443-03

2-(Trifluoromethyl)acrylic acid 98%

Supplier: Thermo Scientific Chemicals
Description: 2-(Trifluoromethyl)acrylic acid 98%

Certificates

Image Unavailable-CAAAAL17169-AP

tert-Butyl acrylate 99% stabilized

Supplier: Thermo Scientific Chemicals
Description: Stab. with 15ppm 4-methoxyphenol

Certificates

Image Unavailable-CA505308-BL

Anti-IL-12/IL-23 Rat Monoclonal Antibody [clone: C17.8]

Supplier: Biolegend
Description: Ultra-LEAF™ Purified anti-mouse IL-12/IL-23 p40 [C17.8]; Isotype: Rat IgG2a, κ; Reactivity: Mouse, IL-12/IL-23 p40 subunit (monomer, homodimer and heterodimer IL-12 p35/p40 or IL-23 p19/p40); Apps: ELISA, Neut, ICFC, IP, WB; Size: 1 mg

Image Unavailable-CA501804-BL

Anti-IL-12 p40 Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: C11.5]

Catalog Number: (CA501804-BL)
Supplier: Biolegend
Description: FITC anti-human IL-12/IL-23 p40 [C11.5]; Isotype: Mouse IgG1, κ; Reactivity: Human, IL-12/IL-23 p40 subunit (monomer, homodimer and heterodimer IL-12 p35/p40 or IL-23 p19/p40); Apps: ICFC; Size: 100 tests
Image Unavailable-10339-894

Anti-IL13RA2 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10339-894)
Supplier: Bioss
Description: Binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4).
Image Unavailable-CAAAAL18071-06

3-(4-Methoxybenzoyl)acrylic acid 98%

Supplier: Thermo Scientific Chemicals
Description: 3-(4-Methoxybenzoyl)acrylic acid 98%

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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