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Product Image-10082-138

Anti-GABARAPL1 Rabbit Polyclonal Antibody

Catalog Number: (10082-138)
Supplier: Proteintech
Description: GABARAPL1 (GABARAP-like protein 1), also named as ATG8, GEC1, APG8L, ATG8L and APG8-LIKE, is a member of GABARP (GABAA receptor-associated protein) family. GABARAPL1 was initially identified as estrogen-regulated gene and the protein acts in receptor and vesicle transport. It’s also involved in the process of autophagy like GABARAP and GABARAPL2, and may be considered as an autophagic marker. It is expressed at very high levels in the brain, heart, peripheral blood leukocytes, liver, kidney, placenta and skeletal muscle and at very low levels in thymus and small intestine.The antibody is specific to GABARAPL1, and it doesn’t recognize the recombinant GABARAP and GABARAPL2.
Product Image-CA77463-310

NIGHTSEA® Tru-Block Eyeshields

Supplier: Electron Microscopy Science
Description: These soft, molded rubber high-sided microscope eye shields extend far enough to truly shield the eyes from any level of ambient light and eliminate distractions for improved viewing of fluorescence subject better.

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Image Unavailable-102978-638

Anti-CASP12 Monoclonal Antibody [clone: 12G6]

Catalog Number: (102978-638)
Supplier: Adipogen
Description: Caspase-12 is a member of the ICE/CED-3 family of caspases and is detected as a protein of ~51kDa. Overexpression of caspase-12 in cells induces apoptosis. Capase-12 is localized to the endoplasmatic reticulum (ER) and activated by ER stress and specifically cleaves and activates pro-caspase-9 and is also thought to be involved in the apoptosis induced by viral infection. Caspase-12-deficient mice are resistant to ER stress-induced apoptosis. Caspase-12 is probably expressed in many and perhaps all mouse tissues and is expressed at high levels in skeletal muscle, heart, lung and kidney and at moderate levels in brain and liver. In many humans caspase-12 is a pseudo gene and not expressed.
Image Unavailable-CAPIPA5-13811

Anti-CKBB Rabbit Polyclonal Antibody

Catalog Number: (CAPIPA5-13811)
Supplier: Thermo Scientific
Description: Creatine Kinase (CK) is a dimeric enzyme composed of either M- or B-type subunits. The resulting isoenzymes are expressed at varying levels in different tissues. CK-BB, a cytoplasmic predominantly found in brain tissues, participates in energy homeostasis, reversibly catalyzing the transfer of a phosphate group between ATP and target proteins such as a creatine phosphate. CK-BB exists in normally neglible amounts in the serum of adults, overexpression of CK-BB is associated with cancers of the breast, ovary, prostate, colon, and in small-cell lung cancer. Global assessment of changes in serum levels of CK-BB, CK-MB and CK-MM, are used as a marker for myocardial infarction.
Product Image-CA83009-426

Accessories for Super Erecta® Wire Shelving, Metroseal 3 Finish, Metro International

Supplier: Metropolitan Wire
Description: For Use With Super Erecta* And Super Erecta Super Adjustable Wire Shelving Systems. Circular Grooves At 2.5Cm Intervals, A Double Groove Every 20.3Cm, Numbers At 5.1Cm Intervals. Height: 138.6Cm. Height Includes Leveling Bolt And Cap.

Image Unavailable-89358-118

Anti-TCRG + TCRD Hamster Monoclonal Antibody [clone: GL3]

Catalog Number: (89358-118)
Supplier: Genetex
Description: T cell receptors (TCR) recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. This region represents the germline organization of the T cell receptor beta locus. The beta locus includes V (variable), J (joining), diversity (D), and C (constant) segments. During T cell development, the beta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The C segment is later joined by splicing at the RNA level.
Image Unavailable-10465-814

Anti-RNF144B Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10465-814)
Supplier: Bioss
Description: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.Tissue specificity: Broadly expressed, with lowest levels in brain and thymus, and highest levels detectable in heart, ovary and testis.
Image Unavailable-10448-482

Anti-ITPR3 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10448-482)
Supplier: Bioss
Description: Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.
Image Unavailable-10448-484

Anti-ITPR3 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10448-484)
Supplier: Bioss
Description: Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.
Image Unavailable-10671-300

Anti-STOML2 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10671-300)
Supplier: Bioss
Description: STOML2 is a 356 amino acid member of the mec-2 family of proteins. Expressed ubiquitously at low levels, STOML2 is highly expressed in heart, liver and pancreas. STOML2 is localized to the cytoplasm with some distribution on the membrane. STOML2 was first identified as an overexpressed protein in human endometrial adenocarcinoma. Changes in cell growth in samples with different levels of STOML2 indicate that STOML2 could play a role in endometrial tumorigenesis. STOML2 is also thought to play a role in regulating ion channel conductances or the organization of sphingolipid and cholesterol-rich lipid rafts.
Image Unavailable-75895-346

Anti-CD3E Mouse Monoclonal Antibody [clone: B-B12]

Supplier: Biotium
Description: This antibody recognizes five invariable CD3 chains (designated as and ) with molecular weight ranging from 16-28 kDa. CD3 is expressed, typically at high levels, on peripheral T cells and majority of T cell neoplasms. Thymocytes express CD3 at different level on the cell surface in the course of differentiation and, in cortical thymus, CD3 is predominantly Intracytoplasmic. The CD3 complex is closely associated at the lymphocyte cell surface with T cell antigen receptor (TCR) and is involved in transducing antigen-recognition signals into cytoplasm of T cells and in regulating the cell surface expression of the TCR complex.

Product Image-CA11006-300

8247 R95 Respirator, 3M™

Supplier: 3M
Description: This respirator provides worker protection against certain oil and non-oil based aerosols including those with nuisance levels of organic vapors such as solvents, degreasers, and resins.

Product Image-470230-886

Number, Measurement, and Space

Catalog Number: (470230-886)
Supplier: Sempco
Description: Teach Elementary-Level Math With Ease!
Image Unavailable-10426-568

Anti-ANGPTL3 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (10426-568)
Supplier: Bioss
Description: Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis. Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin ?v)beta(3). It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain. Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle. A deficiency of Angptl3 results in abnormally low lipid levels, and a repression of the protein may be protective against atherosclerosis. Angptl3 may also play an important role in hyperlipidemia in diabetes.
Image Unavailable-75789-626

Human Recombinant MINPP1 (from Cells)

Catalog Number: (75789-626)
Supplier: Prosci
Description: Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 amino acid precursor that contains an 30 amino acid signal peptide and a 457 amino aicd mature chain. MINPP1 is widely expressed with the highest levels found in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). MINPP1 may play a role in bone development (endochondral ossification).
Product Image-97041-754

Purifier® Cell Logic Accessories, Labconco®

Supplier: Labconco
Description: Purifier Cell Logic Class II Biosafety Cabinets are specially designed with cell researchers in mind, while also providing protection from hazardous particulates such as agents that require Biosafety Level 1,2 or 3 containment.

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