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Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00149792
Supplier: Ricca Chemical
Description: APHA for Phosphorus. Container: Glass.
Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00149674
Supplier: TCI America
Description: CAS Number: 7647-10-1
MDL Number: MFCD00003558
Molecular Formula: Cl2Pd
Molecular Weight: 177.32
Purity/Analysis Method: >98.0% (T)
Form: Crystal
Color: Deep Yellow Red
Melting point (°C): 680
Supplier: Thermo Scientific Chemicals
Description: Tin(II) chloride, anhydrous 98%
Catalog Number: (10095-402)
Supplier: Proteintech
Description: TAF12, also named TAF15 or TAF2J, is a TBP-associated factor that is contained in Pol I- and Pol II-specific TBP-TAF complexes, it is also a component of the transcription factor IID (TFIID) complex, which is essential for mediating regulation of RNA polymerase transcription. TAF12 plays a key role in regulating eukaryotic gene expression by directly binding promoters and enhancer-bound transactivator proteins. Likewise, TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation.


Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00149792
Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00149652 Notes: 52-56°C -4H2O, 100°C -5H2O, 120-140°C -6H2O Fieser: 1,155 6,127 10,101 14,99 15,97 18,107 19,104 20,115 21,142
Catalog Number: (76099-980)
Supplier: Bioss
Description: Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II).


Supplier: Thermo Scientific Chemicals
Description: Iron(II) chloride tetrahydrate 98%
Supplier: TCI America
Description: CAS Number: 12012-95-2
MDL Number: MFCD00044874
Molecular Formula: C6H10Cl2Pd2
Molecular Weight: 365.89
Purity/Analysis Method: >97.0% (T)
Form: Crystal
Catalog Number: (TCP1920-1G)
Supplier: TCI America
Description: CAS Number: 10025-65-7
MDL Number: MFCD00011181
Molecular Formula: PtCl2
Molecular Weight: 265.98
Purity/Analysis Method: >95.0% (W)
Form: Crystal
Color: Pale Yellow
Melting point (°C): 581

Catalog Number: (10494-992)
Supplier: Bioss
Description: Spo11 is a type II topoisomerase that is thought to generate the chromosome breaks that initiate meiotic recombination. The Spo11 protein initiates meiotic recombination by generating DNA double-strand breaks (DSBs) and is required for meiotic synapsis in S. cerevisiae. The DSBs are located mostly in promoter regions, where the chromatin is in an open configuration, and cluster in domains along the chromosome. Expression of the Spo11 is detected mainly in the testis, in agreement with its predicted function in the initiation of meiotic recombination. Disruption of Spo11 leads to severe gonadal abnormalities from defective meiosis and results in infertility.


Supplier: Thermo Scientific Chemicals
Description: Palladium(II) chloride solution (9.0 - 11.0% Pd) (w/w)
Catalog Number: (89415-444)
Supplier: Prosci
Description: IKAP Antibody: IKAP was initially identified as a scaffold protein of the I kappa B kinase complex that could bind to IKK alpha , IKK beta , NF-kappa B, and the NF-kappa B-inducing kinase (NIK), although later evidence has cast doubt on this. More recent reports show that mutations in IKAP such as a frameshift leading to a truncated protein or a missense mutation that leads to defective phosphorylation are responsible for the autosomal recessive genetic disease familial dysautonomia (FD). Reports indicating that it forms part of the RNA polymerase II transcription elongation complex suggest that this disease may be due to compromised transcription elongation. More recently, it was shown that IKAP associates with c-Jun N-terminal kinase (JNK) and could specifically enhance JNK activation induced by the upstream JNK activators MEKK1 and ASK1, indicating another possible cause for FD. At least two isoforms of IKAP are known two exist.


Catalog Number: (10749-416)
Supplier: Prosci
Description: IKAP Antibody: IKAP was initially identified as a scaffold protein of the Ikappa B kinase complex that could bind to IKKalpha , IKKbeta , NF-kappa B, and the NF-kappa B-inducing kinase (NIK), although later evidence has cast doubt on this. More recent reports show that mutations in IKAP such as a frameshift leading to a truncated protein or a missense mutation that leads to defective phosphorylation are responsible for the autosomal recessive genetic disease familial dysautonomia (FD). Reports indicating that it forms part of the RNA polymerase II transcription elongation complex suggest that this disease may be due to compromised transcription elongation. More recently, it was shown that IKAP associates with c-Jun N-terminal kinase (JNK) and could specifically enhance JNK activation induced by the upstream JNK activators MEKK1 and ASK1, indicating another possible cause for FD.


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