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Image Unavailable-10669-402

Anti-CST4 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10669-402)
Supplier: Bioss
Description: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins(stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a type 2 salivary cysteine peptidase inhibitor. The protein is an S-type cystatin, based on its high level of expression in saliva, tears and seminal plasma. The specific role in these fluids is unclear but antibacterial and antiviral activity is present, consistent with a protective function. [provided by RefSeq, Jul2008].
Image Unavailable-76304-086

Human;Mouse;Rat Recombinant Irisin (from CHO cells)

Catalog Number: (76304-086)
Supplier: Peprotech
Description: Irisin is a proteolytic hormone released into circulation by skeletal muscle tissue during acute exercise, and is a derivative of the cleaved plasma membrane protein Fibronectin type III domain-containing protein 5 (FNDC5). Found in muscle tissue, FNDC5 is synthesized at increased levels during exercise as a result of the overexpression of the exercise-responsive transcriptional co-activator PGC-1alpha (peroxisome proliferator-activated receptor-gamma co-activator-1alpha). Like its parent polypeptide, Irisin can induce the browning of subcutaneous adipocytes, or the conversion of white adipose tissue (WAT or white fat) into brown (or beige) adipose tissue (BAT or brown fat). Given that brown fat can undergo thermogenesis, or the physiologic process of heat production, Irisin contributes to the metabolic process by increasing thermogenic function and glucose homeostasis. Irisin, thus, represents a link between exercise and "burning" of fats and/or sugars, and consequently may have relevance in the development of new treatments for diabetes and obesity. CHO cell-derived Recombinant Human/Murine/Rat Irisin is a glycosylated homodimer of 224 amino acid residues, whose monomer consists of 112 amino acid residues corresponding to the active portion of the 121-amino-acid length Irisin extracellular domain. Recombinant Human/Murine/Rat Irisin, appears to form a non-disulfide linked oligomeric structure in solution, has a calculated theoretical molecular weight of 25.2 kDa, but migrates at an apparent molecular weight of 28 kDa by SDS-PAGE analysis under reducing conditions due to glycosylation.
Product Image-CA89261-050

SevenExcellence pH/ION Meters, METTLER TOLEDO®

Catalog Number: (CA89261-050)
Supplier: Mettler Toledo
Description: SevenExcellence pH/Ion meter redefines flexibility and offers various measurements such as pH, mV, rel. mV, and ion concentration in the form of one meter.
Image Unavailable-10448-490

Anti-ITPR3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10448-490)
Supplier: Bioss
Description: Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.
Product Image-CA89400-394

Respirator Cartridges and Filters, Honeywell Safety

Supplier: Honeywell Safety Products
Description: For use with North Safety Products air purifying dual cartridge respirators (see 56222-944 series).

Image Unavailable-10407-086

Anti-APOC3 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10407-086)
Supplier: Bioss
Description: Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors.
Product Image-11010-328

Biodissolution Reciprocating Cylinder Accessories, Apparatus 3, Quality Lab Accessories

Catalog Number: (11010-328)
Supplier: QLA
Description: QLA manufactures Biodissolution Accessories and Glassware for Agilent/VanKel BIO-DIS testers.
Product Image-10797-816

Human Recombinant CD44 (from HEK293 Cells)

Catalog Number: (10797-816)
Supplier: Prosci
Description: CD44 Recombinant Protein, Species: Human, Source: HEK293 cells, Fusion Tag: C-Fc Tag, Purity: >95% as determined by SDS-PAGE, Physical State: Lyopholized, Synonyms: CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, Tested Size: 100UG
Image Unavailable-77437-230

Anti-MMP-3 Rabbit Polyclonal Antibody

Catalog Number: (77437-230)
Supplier: Bioss
Description: Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.
Image Unavailable-H-2592.0025BA

Fibronectin CS-1 Fragment (1978-1982)

Catalog Number: (H-2592.0025BA)
Supplier: Bachem Americas
Description: EILDV and EILDVPST (H-2094) are derived from the type III connecting segment domain (IIICS) of fibronectin and have been found to promote tumor cell attachment after surface immobilization and to inhibit the experimental tumor metastasis of B16-BL6 melanoma. Hereby EILDV showed the strongest effect.
Image Unavailable-10407-084

Anti-APOC3 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10407-084)
Supplier: Bioss
Description: Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors.
Image Unavailable-10407-080

Anti-APOC3 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10407-080)
Supplier: Bioss
Description: Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors.
Product Image-89353-938

Anti-TUBB3 Chicken Polyclonal Antibody

Catalog Number: (89353-938)
Supplier: Genetex
Description: Chicken polyclonal antibody to beta III Tubulin
Image Unavailable-CAAAJ62655-03

Amrinone 98%

Supplier: Thermo Scientific Chemicals
Description: Phosphodiesterase III inhibitor and inhibits platelet aggregation

Certificates

Product Image-CA56222-364

8576 P95 Particulate Respirator with Nuisance Level Acid Gas Relief, 3M™

Catalog Number: (CA56222-364)
Supplier: 3M
Description: Excellent choice for work settings that involve heat, humidity, and long wear periods.
Product Image-27373-531

Owl™ Immobilon™-P Transfer Membranes, PVDF, Thermo Scientific

Supplier: Thermo Fisher Scientific
Description: Hydrophobic polyvinylidene fluoride transfer membrane has a high signal-to-noise ratio, which allows for the use of mild blocking procedures

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