You Searched For: tert-Butylbenzene

Catalog Number: (75791-016)

Supplier: Prosci

Description: NHP2 belongs to the H/ACA snoRNPs gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been organized into 2 families: C/D and H/ACA. NHP2 forms a small ribonucleoprotein particle with GAR1 (NOLA1). NHP2 is involved in a variety of aspects of rRNA processing and modification. NHP2 localizes to the dense fibrillar component of the nucleolus and in nuclear Cajal bodies. NHP2 may also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.

Catalog Number: (10069-756)

Supplier: Prosci

Description: FUNCTION: Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.

Catalog Number: (10101-750)

Supplier: Prosci

Description: NFX1 binds to the X-box motif of MHC class II genes and represses their expression. NFX1 may play an important role in regulating the duration of an inflammatory response by limiting the period in which MHC class II molecules are induced by interferon-gamma. Isoform 3 binds to the X-box motif of TERT promoter and represses its expression. Together with PABPC1 or PABPC4, isoform 1 acts as a coactivator for TERT expression. NFX1 mediates E2-dependent ubiquitination.MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified.

Catalog Number: (76101-454)

Supplier: Bioss

Description: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.

Catalog Number: (76101-456)

Supplier: Bioss

Description: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.

Catalog Number: (10092-342)

Supplier: Proteintech

Description: PINX1, also named as LPTL, LPTS and Protein 67-11-3, is a Liver-related putative tumor suppressor. It belongs to the PINX1 family. PINX1 is a microtubule-binding protein essential for faithful chromosome segregation. It mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. PINX1 inhibits telomerase activity. It may inhibit cell proliferation and act as tumor suppressor. PINX1 has been identified as a critical telomerase inhibitor and proposed to be a putative tumor suppressor gene. Loss of PinX1 has been found in a large variety of malignancies, but the expression status in epithelial ovarian tumors has not been investigated.

Catalog Number: (77438-144)

Supplier: Bioss

Description: Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression. In complex with ATF7IP, maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression.

Catalog Number: (RK30434)

Supplier: Restek

Description: Contains: (C5) n-Pentane (109-66-0), 1,000 µg/mL; (C9) n-Nonane (111-84-2), 1,000 µg/mL; Benzene (71-43-2), 500 µg/mL; Ethylbenzene (100-41-4), 500 µg/mL; 2-Methylpentane (107-83-5), 1,500 µg/mL; Methyl tert-butyl ether (MTBE) (1634-04-4), 1,500 µg/mL; Naphthalene (91-20-3), 1,000 µg/mL; Toluene (108-88-3), 1,500 µg/mL; 1,2,4-Trimethylbenzene (95-63-6), 1,000 µg/mL; 2,2,4-Trimethylpentane (isooctane) (540-84-1), 1,500 µg/mL; m-Xylene (108-38-3), 1,000 µg/mL; o-Xylene (95-47-6), 1,000 µg/mL; p-Xylene (106-42-3), 1,000 µg/mL

SDS

Supplier: Thermo Scientific Chemicals

Description: 4-Butylbenzenesulfonyl chloride 97%

Certificates

Supplier: TCI America

Description: CAS Number: 1571-86-4
MDL Number: MFCD01076591
Molecular Formula: C14H22
Molecular Weight: 190.33
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Specific Gravity (20/20): 0.86

SDS Certificates

Catalog Number: (TCB3773-1G)

Supplier: TCI America

Description: CAS Number: 18979-61-8
MDL Number: MFCD01684800
Molecular Formula: C10H14O2
Molecular Weight: 166.22
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Boiling point (°C): 166
Melting point (°C): 53

SDS Certificates

Catalog Number: (CAAAA15082-14)

Supplier: Thermo Scientific Chemicals

Description: 4-Butylbenzoyl chloride 98%

Certificates

Supplier: TCI America

Description: CAS Number: 79887-09-5
MDL Number: MFCD00173885
Molecular Formula: C12H14
Molecular Weight: 158.24
Purity/Analysis Method: >97.0% (GC)
Form: Clear Liquid
Flash Point (°C): 92
Specific Gravity (20/20): 0.90
Storage Temperature: 0-10°C

SDS Certificates

Catalog Number: (RK30456)

Supplier: Restek

Description: Contains: Benzene (71-43-2); Bromodichloromethane (75-27-4); Bromoform (75-25-2); Carbon disulfide (75-15-0); Carbon tetrachloride (56-23-5); Chlorobenzene (108-90-7); Chloroform (67-66-3); Cyclohexane (110-82-7); Dibromochloromethane (124-48-1); 1,2-Dibromo-3-chloropropane (DBCP) (96-12-8); 1,2-Dibromoethane (EDB) (106-93-4); 1,2-Dichlorobenzene (95-50-1); 1,3-Dichlorobenzene (541-73-1); 1,4-Dichlorobenzene (106-46-7); 1,1-Dichloroethane (75-34-3); 1,2-Dichloroethane (107-06-2); 1,1-Dichloroethene (75-35-4); cis-1,2-Dichloroethene (156-59-2); trans-1,2-Dichloroethene (156-60-5); 1,2-Dichloropropane (78-87-5); cis-1,3-Dichloropropene (10061-01-5); trans-1,3-Dichloropropene (10061-02-6); Ethylbenzene (100-41-4); Isopropylbenzene (cumene) (98-82-8); Methyl acetate (79-20-9); Methyl tert-butyl ether (MTBE) (1634-04-4); Methylcyclohexane (108-87-2); Methylene chloride (dichloromethane) (75-09-2); Styrene (100-42-5); 1,1,2,2-Tetrachloroethane (79-34-5); Tetrachloroethene (127-18-4); Toluene (108-88-3); 1,2,4-Trichlorobenzene (120-82-1); 1,1,1-Trichloroethane (71-55-6); 1,1,2-Trichloroethane (79-00-5); Trichloroethene (79-01-6); 1,1,2-Trichloro-1,2,2-trifluoroethane (CFC-113) (76-13-1); m-Xylene (108-38-3); o-Xylene (95-47-6); p-Xylene (106-42-3).

SDS

Catalog Number: (76234-273)

Supplier: CHI Scientific

Description: L-TERT-LEUCINOL 5G

Catalog Number: (76234-277)

Supplier: CHI Scientific

Description: D-TERT-LEUCINOL 5G