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Image Unavailable-10491-920

Anti-Frataxin Rabbit Polyclonal Antibody

Catalog Number: (10491-920)
Supplier: Bioss
Description: Friedreich ataxia is a progressive neurodegenerative disorder caused by loss of function mutations in the frataxin gene. The human frataxin gene maps to chromosome 9q13.The frataxin gene encodes a mitochondrial protein of the same name. Frataxin assembles into a stable homopolymer with iron-binding capabilities. When expressed in E. Coli human frataxin binds iron atoms at a rate of 10 iron atoms per 1 molecule of the frataxin polymer. Thus, frataxin appears to function in some capacity for iron-storage for the mitochondria. Frataxin may also function as an activator of oxidative phosphorylation to increase mitochondrial membrane potential and elevate cellular ATP. Frataxin is expressed in tissues with high metabolic activity including heart, liver and brown fat.
Product Image-BDH4616-500G

EDTA disodium salt dihydrate 99.0-101.0% ACS, VWR Chemicals BDH®

Catalog Number: (BDH4616-500G)
Supplier: VWR International
Description: Powder.

SDS Certificates


Image Unavailable-CA1.12151.0010

Dysprosium(III) oxide 99, Sigma-Aldrich®

Catalog Number: (CA1.12151.0010)
Supplier: MilliporeSigma
Description: Dysprosium(III) oxide 99, Sigma-Aldrich®

SDS Certificates


Image Unavailable-89150-570

Sodium diethyldithiocarbamate trihydrate ≥99% (by titrimetric analysis)

Catalog Number: (89150-570)
Supplier: Enzo Life Sciences
Description: Nitric oxide (NO) spin-trapping reagent. Thiol and iron chelator. Inhibits induction of macrophage nitric oxide synthase (NOS). Has been shown to be an inhibitor of the nuclear transcription factor κB (NF-κB).
Product Image-CA89106-602

Anti-HMOX1 Rabbit Polyclonal Antibody

Supplier: Enzo Life Sciences
Description: Heme Oxygenase-1 (HO-1) also known as Hsp32, is the inducible isoform of heme oxygenase that catalyzes the NADPH, oxygen, and cytochrome P450 reductase dependent oxidation of heme to carbon monoxide, ferrous iron and biliverdin which is rapidly reduced to bilirubin. These products of the HO reaction have important physiological effects: carbon monoxide is a potent vasodilator and has been implicated to be a physiological regulator of cGMP and vascular tone; biliverdin and its product bilirubin are potent antioxidants; "free" iron increases oxidative stress and regulates the expression of many mRNAs (e.g., DCT-1, ferritin and transferring receptor) by affecting the conformation of iron regulatory protein (IRP)-1 and its binding to iron regulatory elements (IREs) in the 5'- or 3'- UTRs of the mRNAs. To date, three identified heme oxygenase isoforms are part of the HO system that catalyze heme into biliverdin and carbon monoxide. These are inducible HO-1 or Hsp32, constitutive HO-2 that is abundant in the brain and testis, and HO-3 which is related to HO-2 but is the product of a different gene. The HO system is the rate-limiting step in heme degradation and HO activity decreases the levels of heme which is a well known potent catalyst of lipid peroxidation and oxygen radical formation.

Product Image-10111-592

Anti-BLVRB Rabbit Polyclonal Antibody

Catalog Number: (10111-592)
Supplier: Prosci
Description: BLVRB catalyzes electron transfer from reduced pyridine nucleotides to flavins as well as methylene blue, pyrroloquinoline quinone, riboflavin, or methemoglobin. BLVRB has possible role in protecting cells from oxidative damage or in regulating iron metabolism. In the liver, BLVRB converts biliverdin to bilirubin.
Image Unavailable-CA1.12469.0002

Holmium(III) oxide, Sigma-Aldrich®

Catalog Number: (CA1.12469.0002)
Supplier: MilliporeSigma
Description: Holmium(III) oxide, Sigma-Aldrich®

SDS Certificates


Image Unavailable-CAAA12230-30

Bismuth(III) oxide 99%

Supplier: Thermo Scientific Chemicals
Description: In disinfectants, magnets, glass, rubber, vulcanization, in fireproofing papers and polymers, and in catalysts

Certificates

Product Image-89152-480

Ruthenium(III) chloride oxide ≥90% (metals basis)

Catalog Number: (89152-480)
Supplier: Enzo Life Sciences
Description: Blocks TRPV1. Capsaicin and calcium antagonist. Inhibitor of Ca2+/Mg2+-ATPase.
Image Unavailable-CAAA11265-A1

Lanthanum(III) oxide ≥99.999% (REO, rare earth oxide basis), REacton®

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00011071

Certificates

Image Unavailable-CAAA11272-22

Lanthanum(III) oxide ≥99.9% (REO, rare earth oxide basis), REacton®

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00011071

Certificates

Image Unavailable-CAAAA44594-30

Praseodymium(III,IV) oxide ≥99% (REO, rare earth oxide basis)

Supplier: Thermo Scientific Chemicals
Description: Praseodymium(III,IV) oxide ≥99% (REO, rare earth oxide basis)

Certificates

Image Unavailable-CAAA40394-18

Bismuth(III) oxide 99.975% (metals basis)

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00003462

Certificates

Image Unavailable-CA1.12201.0005

Indium (III) oxide 99,5, Sigma-Aldrich®

Catalog Number: (CA1.12201.0005)
Supplier: MilliporeSigma
Description: Indium (III) oxide 99,5, Sigma-Aldrich®
Image Unavailable-CAAA11199-04

Thulium(III) oxide ≥99.99% (REO, rare earth oxide basis), REacton®

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00011285

Certificates

Image Unavailable-77439-198

Anti-SOD2 Rabbit Polyclonal Antibody

Catalog Number: (77439-198)
Supplier: Bioss
Description: This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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