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Catalog Number: (10750-270)
Supplier: Prosci
Description: CAPN6 Antibody: Calpains make up a ubiquitously expressed, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. This large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes as their activation can be triggered by calcium influx and oxidative stress. Calpain 6 (CAPN6) is most similar to Calpain 5; the C-terminal region of CAPN6 lacks homology to the calmodulin-like domain of other vertebrate calpains. CAPN6 is thought to be involved in the regulation of microtubule dynamics and cytoskeletal organization. CAPN6 has also been recently identified as an HIV dependency factor (HDF), suggesting that CAPN6 may be an important drug target in HIV treatment.


Catalog Number: (10390-112)
Supplier: Bioss
Description: This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity).


Catalog Number: (10106-532)
Supplier: Prosci
Description: CACNB2 is a subunit of voltage-dependent calcium channel


Catalog Number: (10106-456)
Supplier: Prosci
Description: ANXA11 is a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain the calcium-dependent phospholipid-binding sites. The encoded protein is a 56-kD antigen recognized by sera from patients with various autoimmune diseases. Transcript variants encoding the same isoform have been identified.


Catalog Number: (76116-798)
Supplier: Bioss
Description: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Increases the apparent Ca2+/voltage sensitivity of the KCNMA1 channel. It also modifies KCNMA1 channel kinetics and alters its pharmacological properties. It slows down the activation and the deactivation kinetics of the channel. Acts as a negative regulator of smooth muscle contraction by enhancing the calcium sensitivity to KCNMA1. Its presence is also a requirement for internal binding of the KCNMA1 channel opener dehydrosoyasaponin I (DHS-1) triterpene glycoside and for external binding of the agonist hormone 17-beta-estradiol (E2). Increases the binding activity of charybdotoxin (CTX) toxin to KCNMA1 peptide blocker by increasing the CTX association rate and decreasing the dissociation rate.


Catalog Number: (10108-744)
Supplier: Prosci
Description: Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Each troponin-tropomyosin complex contains 1 molecule from each of the 3 troponins: T, C, and I. The troponin I (TNI) subfamily contains three genes: TNI-skeletal-fast-twitch, TNI-skeletal-slow-twitch, and TNI-cardiac. TNNI1 prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.


Catalog Number: (CA97013-286)
Supplier: PerkinElmer
Description: Multi-element Lumina™ Hollow Cathode Lamp (HCL) for the detection of elemental Calcium (Ca) and Magnesium (Mg). Series N30502XX Lumina™ 2" (50 mm) diameter multi-element lamps are designed to be used with PerkinElmer PinAAcle™ and AAnalyst™ Atomic Absorption (AA) spectrometer series of instruments.


Catalog Number: (10782-002)
Supplier: Biosensis
Description: Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. COFACTOR: Binds 2 calcium ions per subunit.


Catalog Number: (10368-580)
Supplier: Bioss
Description: PYK2 is involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. PKY2 may represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage gated potassium channel protein Kv1.2. PYK2 activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity.


Catalog Number: (89165-946)
Supplier: Enzo Life Sciences
Description: Calcium dye


Catalog Number: (104088-218)
Supplier: Hach
Description: Digital titration provides a more precise and accurate method than the drop test method.

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Catalog Number: (10085-006)
Supplier: Proteintech
Description: COMM domain containing 5 (COMMD5, synonyms: HCARG, HT002) is a hypertension-related calcium-regulated gene. COMMD5 is negatively regulated by extracellular calcium concentration, and its basal mRNA levels were higher in hypertensive animals. Tissue distribution of COMMD5 shows a preponderance in the heart, stomach, jejunum, kidney (tubular fraction), liver, and adrenal gland (mainly in the medulla). COMMD5 mRNA is significantly more expressed in adult than in fetal organs, and its levels are decreased in tumors and cancerous cell lines. COMMD5 protein has no transmembrane domain, but contains 67% -helix content, a calcium-binding site, four putative "leucine zipper" motifs, and a nuclear receptor-binding domain. At the subcellular level, COMMD5 shows a nuclear localization.


Catalog Number: (76101-820)
Supplier: Bioss
Description: In plant cells, the vacuole functions as a major calcium store. Although a calmodulin-regulated Ca2+-ATPase (ACA4) is known to be present in prevacuolar compartments, the presence of an ACA-type Ca2+-ATPase in the mature vacuole of a plant cell has not been verified. Here we provide evidence that ACA11 localizes to the vacuole membrane. ACA11 tagged with GFP was expressed in stable transgenic plants, and visualized in root cells and protoplasts by confocal microscopy. A Ca2+-ATPase function for ACA11 was confirmed by complementation of yeast mutants.


Catalog Number: (BDH9256-500G)
Supplier: VWR International
Description: Meets reagent specifications for testing USP/NF monographs.

Catalog Number: (103005-972)
Supplier: Anaspec Inc
Description: A 18-amino acid peptide from bee venom, a selective blocker of calcium activated potassium channels.
Sequence:CNCKAPETALCARRCQQH-NH2 (Disulfide bridge: 1-11; 3-15)
MW:2027.4 Da
% peak area by HPLC:95
Storage condition:-20° C


Supplier: Thermo Scientific Chemicals
Description: Inhibits intracellular calcium mobilization
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