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Product Image-89415-780

Anti-CASP2 Rabbit Polyclonal Antibody

Catalog Number: (89415-780)
Supplier: Prosci
Description: Caspase-2 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1 beta and IL-18. Although phylogenetically similar to this subfamily, Caspase-2 is thought to be involved in stress-induced apoptosis. Caspase-2 has two major isoforms; overexpression on the long form results in apoptosis while that of the short form suppresses cell death.
Product Image-10099-572

Anti-ATF6B Rabbit Polyclonal Antibody

Catalog Number: (10099-572)
Supplier: Prosci
Description: ATF6B (CREBL1) is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. ATF6B is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.The protein encoded by this gene bears sequence similarity with the Creb/ATF subfamily of the bZip superfamily of transcription factors. It localizes to both the cytoplasm and the nucleus. The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6.
Image Unavailable-102979-288

Anti-TG Monoclonal Antibody [clone: 2E8]

Catalog Number: (102979-288)
Supplier: Adipogen
Description: Thymidineglycol (TG) is one of the major oxidation products of DNA. Thymidine (T) can be damaged by oxidative stress such as radiation and energy metabolism. Two different pathways to form TG have been suggested. Deoxythymidine in DNA is directly oxidised by hydroxy radical, to form TG. TG can be also formed through an intermediate thymidine chlorohydrin, which is derived from hypochlorous acid (HOCl) from neutrophil myeloperoxidase. Thymidineglycol is derived from DNA, not from RNA. TG is the oxidative stress marker secific for DNA damage. In comparison with 8-hydroxy-2'-deoxyguanosine (8-OHdG), which is the best known DNA oxidation product it was shown that in a lipopolysaccharide (LPS)-treated mouse liver, 8-OHdG can be stained within 24 hours after LPS treatment. TG can be detected within 6 hours, and remains at least for 72 hours.
Product Image-10107-586

Anti-HSPBAP1 Rabbit Polyclonal Antibody

Catalog Number: (10107-586)
Supplier: Prosci
Description: HSPBAP1 may play a role in cellular stress response.
Product Image-76045-874

Cole-Parmer® SHM-250 Series Digi-Mantle Heating Kits, Antylia Scientific

Supplier: Antyila Scientific
Description: Heating kit includes a heating mantle controller and interchangeable heating cartridge.

Product Image-75840-108

VWR® Basic Melting Point Apparatus

Supplier: VWR International
Description: The VWR® Basic Melting Point Apparatus is primarily used in determining the purity of a sample and is optimized to quickly and efficiently heat up to 3 samples at one time.

Environmentally Preferable Product available on GSA Advantage®

Image Unavailable-10372-050

Anti-MSK1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10372-050)
Supplier: Bioss
Description: MSK1 is a mitogen and stress activated protein kinase 1 which belongs to the AGC family of kinases and is related in structure to the ribosomal p70 S6 kinase subfamily. MSK1 can be activated by ERK1/2 and SAPK2/p38 MAP kinase. It is also known to be required for the phosphorylation of CREB, ATF1 H3 and HMG14 in response to mitogen and stress. Similar to RSK, MSK1 contains two kinase domains (N term and a C term). Once phosphorylated on Thr581 and Ser360 by ERK1/2 and SAPK2/p38, MSK1 autophosphorylate on at least 5 sites. Of these autophosphorylation sites Ser212 and Ser376 get phosphorylated by the C terminal kinase domain of MSK1 which is essential for the catalytic activity of the N terminal kinase domain.
Product Image-10372-086

Anti-MSK1 Rabbit Polyclonal Antibody

Catalog Number: (10372-086)
Supplier: Bioss
Description: MSK1 is a mitogen and stress activated protein kinase 1 which belongs to the AGC family of kinases and is related in structure to the ribosomal p70 S6 kinase subfamily. MSK1 can be activated by ERK1/2 and SAPK2/p38 MAP kinase. It is also known to be required for the phosphorylation of CREB, ATF1 H3 and HMG14 in response to mitogen and stress. Similar to RSK, MSK1 contains two kinase domains (N term and a C term). Once phosphorylated on Thr581 and Ser360 by ERK1/2 and SAPK2/p38, MSK1 autophosphorylate on at least 5 sites. Of these autophosphorylation sites Ser212 and Ser376 get phosphorylated by the C terminal kinase domain of MSK1 which is essential for the catalytic activity of the N terminal kinase domain.
Image Unavailable-10369-820

Anti-MSK1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10369-820)
Supplier: Bioss
Description: MSK1 is a mitogen and stress activated protein kinase 1 which belongs to the AGC family of kinases and is related in structure to the ribosomal p70 S6 kinase subfamily. MSK1 can be activated by ERK1/2 and SAPK2/p38 MAP kinase. It is also known to be required for the phosphorylation of CREB, ATF1 H3 and HMG14 in response to mitogen and stress. Similar to RSK, MSK1 contains two kinase domains (N term and a C term). Once phosphorylated on Thr581 and Ser360 by ERK1/2 and SAPK2/p38, MSK1 autophosphorylate on at least 5 sites. Of these autophosphorylation sites Ser212 and Ser376 get phosphorylated by the C terminal kinase domain of MSK1 which is essential for the catalytic activity of the N terminal kinase domain.
Image Unavailable-10372-082

Anti-MSK1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10372-082)
Supplier: Bioss
Description: MSK1 is a mitogen and stress activated protein kinase 1 which belongs to the AGC family of kinases and is related in structure to the ribosomal p70 S6 kinase subfamily. MSK1 can be activated by ERK1/2 and SAPK2/p38 MAP kinase. It is also known to be required for the phosphorylation of CREB, ATF1 H3 and HMG14 in response to mitogen and stress. Similar to RSK, MSK1 contains two kinase domains (N term and a C term). Once phosphorylated on Thr581 and Ser360 by ERK1/2 and SAPK2/p38, MSK1 autophosphorylate on at least 5 sites. Of these autophosphorylation sites Ser212 and Ser376 get phosphorylated by the C terminal kinase domain of MSK1 which is essential for the catalytic activity of the N terminal kinase domain.
Image Unavailable-10088-530

Anti-HTRA2 Rabbit Polyclonal Antibody

Catalog Number: (10088-530)
Supplier: Proteintech
Description: HTRA2(High temperature requirement protein A2) is also named as OMI, PRSS25 and belongs to the peptidase S1B family. HTRA2 normally exists in the mitochondria, can cause MMP3 activation in the cytosol under a cell stress condition, which can ultimately lead to demise of dopaminergic neuronal cells. It inhibits mitochondrial superoxide generation, stabilizes mitochondrial membrane potential, and prevents apoptosis at baseline and in response to extracellular inducers of mitochondrial stress. This protein has 4 isoforms produced by alternative splicing.
Image Unavailable-CAPIPA5-13953

Anti-MKNK2 Rabbit Polyclonal Antibody

Catalog Number: (CAPIPA5-13953)
Supplier: Thermo Scientific
Description: MKNK2 may play a role in the response to environmental stress and cytokines. This protein appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.
Product Image-57800-258

Digital Sound Meter, Sper Scientific

Supplier: Sper Scientific
Description: Ideal for testing for OSHA requirements.

Product Image-76047-262

VWR® TraceableLIVE® Wi-Fi Datalogging CO₂ with Remote Notification

Catalog Number: (76047-262)
Supplier: VWR International
Description: VWR® TraceableLIVE® is the simple, efficient, and reliable way to stay connected to critical environments, wherever you go.
Product Image-80070-710

Funnels, Addition, Graduated, PTFE Metering Stopcocks, Chemglass

Supplier: Chemglass
Description: Cylindrical style addition funnels feature a PTFE adjustable bore metering plug.

Small Business Enterprise

Product Image-75881-080

Pro20i Dissolved Oxygen Instrument, YSI

Catalog Number: (75881-080)
Supplier: YSI
Description: Dissolved oxygen and temperature handheld instrument with integral (i.e. non-detachable) cable. The Pro20i is a direct replacement for the model 55 and 550A dissolved oxygen instruments.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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