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Image Unavailable-10354-610

Anti-CHUK Rabbit Polyclonal Antibody

Catalog Number: (10354-610)
Supplier: Bioss
Description: Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. Negatively regulates the pathway by phosphorylating the scaffold protein TAXBP1 and thus promoting the assembly of the A20/TNFAIP3 ubiquitin-editing complex (composed of A20/TNFAIP3, TAX1BP1, and the E3 ligases ITCH and RNF11). Therefore, CHUK plays a key role in the negative feedback of NF-kappa-B canonical signaling to limit inflammatory gene activation. As part of the non-canonical pathway of NF-kappa-B activation, the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB, inducing its proteolytic processing to NFKB2/p52 and the formation of NF-kappa-B RelB-p52 complexes. In turn, these complexes regulate genes encoding molecules involved in B-cell survival and lymphoid organogenesis. Participates also in the negative feedback of the non-canonical NF-kappa-B signaling pathway by phosphorylating and destabilizing MAP3K14/NIK. Within the nucleus, phosphorylates CREBBP and consequently increases both its transcriptional and histone acetyltransferase activities. Modulates chromatin accessibility at NF-kappa-B-responsive promoters by phosphorylating histones H3 at 'Ser-10' that are subsequently acetylated at 'Lys-14' by CREBBP. Additionally, phosphorylates the CREBBP-interacting protein NCOA3.
Image Unavailable-CA80503-718

B-GLUCAN, SACCHAROMYCES CEREVI

Catalog Number: (CA80503-718)
Supplier: MilliporeSigma
Description: B-GLUCAN, SACCHAROMYCES CEREVI

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Product Image-76851-120

Anti-GBE1 Rabbit Polyclonal Antibody

Catalog Number: (76851-120)
Supplier: ANTIBODIES.COM LLC
Description: Rabbit polyclonal antibody to GBE1 for WB with samples derived from Human, Mouse and Rat.
Product Image-77830-686

Anti-GBE1 Rabbit Recombinant Polyclonal Antibody

Supplier: AFG Bioscience
Description: Anti-GBE1 Rabbit Recombinant Polyclonal Antibody

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Image Unavailable-76763-510

Anti-GBE1 Rabbit Polyclonal Antibody

Catalog Number: (76763-510)
Supplier: Prosci
Description: Anti-GBE1 Rabbit Polyclonal Antibody
Product Image-77528-396

Horse Amya (Amylase Alpha) ELISA Kit

Catalog Number: (77528-396)
Supplier: AFG Bioscience
Description: Horse Amya (Amylase Alpha) ELISA Kit
Product Image-77528-748

Mouse AMY1 (Amylase Alpha 1, Salivary) ELISA Kit

Catalog Number: (77528-748)
Supplier: AFG Bioscience
Description: Mouse AMY1 (Amylase Alpha 1, Salivary) ELISA Kit
Product Image-77523-478

Rat AMY1 (Amylase Alpha 1, Salivary) ELISA Kit

Catalog Number: (77523-478)
Supplier: AFG Bioscience
Description: Rat AMY1 (Amylase Alpha 1, Salivary) ELISA Kit
Product Image-76869-030

Anti-Pancreatic alpha amylase Rabbit Polyclonal Antibody

Catalog Number: (76869-030)
Supplier: ANTIBODIES.COM LLC
Description: Rabbit polyclonal antibody to Pancreatic alpha amylase for WB with samples derived from Human, Mouse and Rat.
Image Unavailable-CA82603-816

Fungi Glucoamylase (from Rhizopus spp.)

Catalog Number: (CA82603-816)
Supplier: MilliporeSigma
Description: Fungi Glucoamylase (from Rhizopus spp.)

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Product Image-77514-108

Human MGA (Maltase Glucoamylase, Intestinal) ELISA Kit

Catalog Number: (77514-108)
Supplier: AFG Bioscience
Description: Human MGA (Maltase Glucoamylase, Intestinal) ELISA Kit
Product Image-77077-368

Anti-EXO1 Goat Polyclonal Antibody

Catalog Number: (77077-368)
Supplier: ANTIBODIES.COM LLC
Description: Goat polyclonal antibody to EXO1 for ELISA and WB with samples derived from Human.
Product Image-77513-424

Human AMY1 (Amylase Alpha 1, Salivary) ELISA Kit

Catalog Number: (77513-424)
Supplier: AFG Bioscience
Description: Human AMY1 (Amylase Alpha 1, Salivary) ELISA Kit
Product Image-77513-780

Human Amya (Amylase Alpha) ELISA Kit

Catalog Number: (77513-780)
Supplier: AFG Bioscience
Description: Human Amya (Amylase Alpha) ELISA Kit
Product Image-77528-822

Rat Amya (Amylase Alpha) ELISA Kit

Catalog Number: (77528-822)
Supplier: AFG Bioscience
Description: Rat Amya (Amylase Alpha) ELISA Kit
Product Image-77525-564

Mouse CLEC7A (C-Type Lectin Domain Family 7, Member A) ELISA Kit

Catalog Number: (77525-564)
Supplier: AFG Bioscience
Description: Mouse CLEC7A (C-Type Lectin Domain Family 7, Member A) ELISA Kit
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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  • issued document with your organization's Federal Tax ID Number
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