You Searched For: Formamidine+disulfide+dihydrochloride

Catalog Number: (103008-246)

Supplier: Anaspec Inc

Description: Pramlintide is the first in the new class of amylinomimetic compounds and is a synthetic analogue of the human hormone Amylin, a 37 amino acid peptide. Pramlintide’s peptide sequence differs from Amylin by replacing proline at postitions 25, 28, and 29. Pramlintide has a disulfide bridge between C2 and C7. For Research Use Only.
Sequence: KCNTATCATQRLANFLVHSSNNFGPILPPTNVGSNTY-NH2 (S-S Bond) acetate salt
MW: 3949.5 Da
% Peak Area by HPLC: ≥ 95%
Storage condition: -20°C

Catalog Number: (CAPIM807)

Supplier: Thermo Scientific

Description: The M807 anti-EGF antibody has successfully been paired as the detection antibody in a sandwich ELISA with coating antibody MA805 (Clone 1H11). Typical dilutions for sandwich ELISA: Coat = 1-3 µg/ml and Detection = 0.125-0.5 µg/ml. The protein encoded by EGF gene is a growth factor that stimulates cell growth, proliferation, and differentiation by binding to its receptor EGFR. Human EGF is a 6045-Da protein with 53 amino acid residues and three intramolecular disulfide bonds.

Supplier: Bachem Americas

Description: BNP, originally isolated from porcine brain, belongs to the class of natriuretic peptides, having an amino acid sequence and a pharmacological activity spectrum (including diuretic-natriuretic, hypotensive, and vasorelaxant actions) remarkably similar to that of atrial natriuretic peptide (ANP). Meanwhile, BNP precursor molecules have also been shown to exist in human and rat cardiac tissue. Comparison of the precursor sequences demonstrates structural species differences between the mammalian BNPs, a finding which contrasts with the highly conserved ANP sequences.

Supplier: Bachem Americas

Description: The amyloidogenic peptide hormone amylin 1-37 (or Islet Amyloid Polypeptide, IAPP), KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY amide, has been isolated from the amyloid-rich pancreases of diabetic patients. IAPP forms fibrillar peptide deposits in the pancreatic islets of Langerhans, which may be related to death of the insulin-producing islet β-cells in type 2 diabetes mellitus.

Catalog Number: (10087-908)

Supplier: Proteintech

Description: GSR(Glutathione reductase) is also named as GLUR, GRD1 and belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.It was first found in a black American a variant red cell GSR characterized by greater electrophoretic mobility and enzyme activity per unit of hemoglobin than the normal.This protein maintains high levels of reduced glutathione in the cytosol.It has 5 isoforms produced by alternative splicing and alternative initiation.It can also exsit as a homodimer with the molecular weight of 110KDa.This antibody is specific to GSR.

Supplier: Peprotech

Description: EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor). Recombinant Rat EGF is a 6.2 kDa globular protein containing 54 amino acid residues, including 3 intramolecular disulfide bonds.

Catalog Number: (75908-962)

Supplier: Biotium

Description: CD98 exits as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.

Catalog Number: (10070-692)

Supplier: Prosci

Description: Thioredoxin (TRX) is a small ubiquitous protein (MW12 kDa) which is exist in a wide variety of prokaryotic and eukaryotic cells. Trx contains a redox active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site.This antibody is suitable for detecting fusion proteins which encode a Trx-Tag by immunoblotting and immunoprecipitation.The Monoclonal Antibody can detect a little Trx-Tag fusion proteins with negligible cross-reactivity with bacterial, insect, or mammalian lysates.

Catalog Number: (10061-970)

Supplier: Prosci

Description: CD160, also known as BY55, is a lipid-anchored cell membrane glycoprotein that contains one immunoglobulin-like domain. It is expressed in small intestine, spleen and functional NK and T cytotoxic lymphocytes (1,2). CD160 exists as a disulfide-linked homomultimer that functions as a receptor for MHC (major histocompatability complex) molecules and is thought to regulate the function of NK cells. Additionally, CD160 interacts with TNFRSF14 and, via this interaction, is able to negatively regulate CD4+ T cell activation, indicating a role in immune system regulation.

Catalog Number: (10073-216)

Supplier: Prosci

Description: CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds.It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine-protein kinase p56lck.

Catalog Number: (10752-052)

Supplier: Prosci

Description: CD160, also known as BY55, is a lipid-anchored cell membrane glycoprotein that contains one immunoglobulin-like domain. It is expressed in small intestine, spleen and functional NK and T cytotoxic lymphocytes. CD160 exists as a disulfide-linked homomultimer that functions as a receptor for MHC (major histocompatability complex) molecules and is thought to regulate the function of NK cells. Additionally, CD160 interacts with TNFRSF14 and, via this interaction, is able to negatively regulate CD4+ T cell activation, indicating a role in immune system regulation.

Catalog Number: (10089-636)

Supplier: Proteintech

Description: LSR (lipolysis stimulated lipoprotein receptor) is a lipoprotein receptor primarily expressed in the liver and activated by free fatty acids . This remnant receptor binds both apoB- and apoE-containing lipoproteins and displays greastest affinity for TG-rich lipoproteins. Distribution of LSR causes embryonic lethality in mice, indicating that the expression of LSR is critical for liver and embryonic development . Investigations show that LSR is a multimer consisting of α subunit (68 kDa) and β subunit (56 kDa) associated through disulfide bridges .

Supplier: Peprotech

Description: Amphiregulin is an EGF-related growth factor that signals through the EGF/TGF-α receptor, and stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, Amphiregulin’s extracellular domain is proteolytically processed to release the mature protein. There are 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity. Recombinant Human Amphiregulin is an 11.3 kDa glycoprotein consisting of 98 amino acid residues.

Catalog Number: (10089-346)

Supplier: Proteintech

Description: KLRG1 (killer cell lectin-like receptor subfamily G, member 1) is a C-type lectin inhibitory receptor that contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. KLRG1 is expressed by subsets of NK and T cells, existing both as a monomer and as a disulfide-linked homodimer . It is considered to be a cell differentiation marker for NK and T cells and is strongly induced by viral and other infections . Through interactions with members of the cadherin family, KLRG1 plays an inhibitory role on NK- and T-cell function .

Supplier: Biotium

Description: CD98 exits as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.

Catalog Number: (10751-536)

Supplier: Prosci

Description: SPINK2 Antibody: Human serine proteinase inhibitor Kazal-type 2 (SPINK2) is required for maintaining normal spermatogenesis and potentially regulates serine protease-mediated apoptosis in male germ cells. It contains a typical kazal domain composed by six cysteine residues forming three disulfide bridges. SPINK2 functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. SPINK2 plays a role in the pathogenesis of hereditary and chronic pancreatitis.