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Catalog Number: (89359-178)
Supplier: Genetex
Description: In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]).[supplied by OMIM]


Catalog Number: (470123-390)
Supplier: United Product & Instrument
Description: The 1100RS Visible Spectrophotometer features an accurate 10nm bandpass model and is designed for use with <sup>1</sup>/<sub>2</sub>" (13 mm) round tubes or 10mm square cuvettes and is perfect for most laboratory/classroom applications. An adapter is supplied at no additional charge for 10 mm square optical glass cuvettes. The high quality silicon photodiode detector and 1200 lines/mm grating assures high performance. Auto zero function, one-touch blanking and built-in, automatic filters allow for easy operation. The large digital display allows for quick and easy readings. This visible spectrophotometer works with optional Windows® based software for easy data collection and application expansion to Standard Curve and Kinetics, Abs. and %T and Concentration, etc. Data can be easily exported to Microsoft Excel® for further processing and analysis. The software is designed for Windows based PCs using Windows® 2000, ME, or XP. A USB and RS-232 port is available on this spectrophotometer as well as Absorbance, Transmittance, Concentration (C) and Factor (F) modes. Each mode can be quickly selected with the touch of a button.


Catalog Number: (77438-580)
Supplier: Bioss
Description: Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).[supplied by OMIM, Mar 2008].


Supplier: NABERTHERM INC.
Description: These weighing furnaces with integrated precision scale and software, were designed especially for determining combustion loss in the laboratory. The determination of combustion loss is necessary, for instance, when analyzing sludges. Combustion loss is defined as the difference between the initial total mass and the combustion residue. During the process the software supplied records both temperature and weight loss.

Supplier: NABERTHERM INC.
Description: These weighing furnaces with an integrated precision scale and software, were designed especially for determining combustion loss in the laboratory. The determination of combustion loss is necessary, for instance, when analyzing sludges. Combustion loss is defined as the difference between the initial total mass and the combustion residue. During the process the software supplied records both temperature and weight loss.

Catalog Number: (10204-980)
Supplier: ANDalyze Inc
Description: The AND1100 Fluorimeter tests for metals in water in two steps and less than two minutes, significantly reducing the test expenditures, complexity and wait times experienced in traditional tests. Powered by DNA, it is a breakthrough in streamlining the water analysis and reporting processes. The AND1100 Fluorimeter is a platform centric portable device for heavy metals testing for drinking water and industrial water supplies. It uses an extremely sensitive measurement technique in tandem with ANDalyze sensor kits to determine the toxicity levels of heavy metal contamination. Sensor kits are available for lead, uranium, copper, mercury, zinc, and cadmium; with more to come.


Catalog Number: (89358-238)
Supplier: Genetex
Description: Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).[supplied by OMIM]


Catalog Number: (CA80500-030)
Supplier: MilliporeSigma
Description: Synthetic peptide corresponding to amino acids 1–42 of the processed human amyloid peptide. Supplied in a form that is not neurotoxic prior to preincubation. The level of toxicity has recently been shown to correlate to the extent of beta sheet structure. Reconstitute with degassed HPLC grade deionized water.

Catalog Number: (89358-050)
Supplier: Genetex
Description: KIFC3 belongs to the large superfamily of kinesins, molecular motors that use the energy of ATP hydrolysis to translocate cargoes along microtubules. Members share extensive homology within a globular domain containing the microtubule- and ATP-binding sites and have a coiled-coil stalk domain that mediates oligomerization. Different kinesin family members participate in specific and diverse motile processes, such as cell division, organelle transport, and nuclear movement (Hoang et al., 1998 [PubMed 9782090]).[supplied by OMIM]


Supplier: Lonza
Description: IsoGel® Precast agarose IEF plates provide rapid and reproducible isoelectric focusing of proteins up to 2000 kDa.
Catalog Number: (89361-204)
Supplier: Genetex
Description: Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO (see MIM 165370), RAC (see RAC1; MIM 602048), and CDC42 (MIM 116952). GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.[supplied by OMIM]


Catalog Number: (11376-290)
Supplier: TrippNT
Description: White PVC top loader workstation has all the features you need to consolidate and stream-line your processes.

Small Business Enterprise Minority or Woman-Owned Business Enterprise


Supplier: Restek
Description: These general-purpose columns are designed for solvent impurities, PCB congeners, simulated distillation, drugs of abuse, gases, natural gas odorants, sulfur compounds, essential oils, hydrocarbons, semi-volatiles, pesticides, and oxygenates.

Supplier: SPEX CERTIPREP LLC
Description: Consumer Safety Standards
Analytical Standards for Wine

Wine is a complex combination of water, alcohol and other substances such as organic acids, phenols, sugars, carbon dioxide, and sulfur dioxide. The chemical interactions of these compounds, combined with the aging process, determine the quality of the color, taste and aroma of the wine. However, during this process, the chemical interactions can also play key roles in spoiling the wine. For instance, cork taint transpires when naturally occurring airborne fungi are in the presence of chlorophenol compounds to form 2,4,6-trichloranisole (TCA) in the wine. When this occurs, the wine’s aroma is reduced significantly and is replaced by an undesirable smell and taste.

To help regulate the spoilage of wine, the wine industry tests for several compounds that are known to cause this. For this industry, SPEX CertiPrep offers Certified Reference Materials (CRMs) for wine that are designed for GC, GC/MS, HPLC and LC/MS analysis. These standards are manufactured from the highest purity starting materials and the highest grade of solvents available in order to guarantee superior quality. Each standard is supplied with a detailed comprehensive Certificate of Analysis.

Catalog Number: (10105-494)
Supplier: Prosci
Description: Iron-sulfur clusters are required for the function of many cellular enzymes. The protein encoded by this gene supplies inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH. The encoded protein belongs to the class-V family of pyridoxal phosphate-dependent aminotransferases. Two transcript variants encoding two different isoforms have been found for this gene.


Catalog Number: (10101-470)
Supplier: Prosci
Description: Chromosomal protein HMG14 (HMGN1) and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.Chromosomal protein HMG14 and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.


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