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520 MMP FRET Substrate VII, QXL™ 520-FAM, AnaSpec

Catalog Number: (103003-250)

Supplier: Anaspec Inc

Description: Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This peptide is a sensitive substrate for assaying MMP-7, 12 and 13 activities, Abs/Em = 494/521 nm.
Sequence:QXL™ 520-PYAYWMRK(5-FAM)-NH2
MW:1963.1 Da
% peak area by HPLC:95
Storage condition:-20° C

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520 MMP FRET Substrate XIV, QXL™ 520-FAM, AnaSpec

Catalog Number: (103005-942)

Supplier: Anaspec Inc

Description: Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This peptide is a sensitive substrate for assaying MMP-1, 2, 3, 7, 8, 9, 12, and 13 activities, Abs/Em = 494/521 nm.
Sequence:QXL™ 520 -γ-Abu-P-Cha-Abu-Smc-HA-Dab(5-FAM)-AK-NH2 (Smc=S-Methyl-L-cysteine)
MW:1913.1 Da
% peak area by HPLC:95
Storage condition:-20° C

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5(6)-Carboxyfluorescein ≥95% (by HPLC) fluorescent pH indicator

Catalog Number: (89139-248)

Supplier: Biotium

Description: 5-(and-6)-FAM (full name: 5-(and-6)-Carboxyfluorescein mixed isomer) has a pKa of 6.5 and can be used as a pH indicator. Its excitation spectrum and fluorescence response to pH are similar to those of BCECF. Carboxyfluorescein can also be used as a tracer dye. The dye is membrane-impermeant and can be loaded into cells by microinjection or scrape loading.

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Orbit Atoms, Bonds and Accessories

Catalog Number: (470320-302)

Supplier: Cochranes of Oxford

Description: Order extra atoms, bonds, and accessories to supplement your Minit® Sets.

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Reactive Dye Conjugates, Biotium

Supplier: Biotium

Description: Reactive dyes containing an amine functional group.

5-Carboxyfluorescein ≥98% (by HPLC) fluorescent pH indicator

Catalog Number: (89139-260)

Supplier: Biotium

Description: 5-Carboxyfluorescein has a pKa of 6.5 and can be used as a pH sensor. The excitation spectrum of the dye responds to pH similarly to that of BCECF. Carboxyfluorescein can also be used as a tracer dye. The dye is membrane-impermeant and can be loaded into cells by microinjection or scrape loading.

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6-Carboxyfluorescein ≥98% (by HPLC) fluorescent pH indicator

Catalog Number: (89139-262)

Supplier: Biotium

Description: 6-Carboxyfluorescein has a pKa of 6.5 and can be used as a pH sensor. The excitation spectrum of the dye responds to pH similarly to that of BCECF. Carboxyfluorescein can also be used as a tracer dye. The dye is membrane-impermeant and can be loaded into cells by microinjection or scrape loading.

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Renin 520 Peptide

Catalog Number: (103007-076)

Supplier: Anaspec Inc

Description: This FRET peptide is a specific substrate for renin. This renin peptide substrate may be used for screening of renin inhibitors. In the FRET peptide, the fluorescence of 5-FAM is quenched by QXL® 520. Upon cleavage into two separate fragments by renin, the fluorescence of 5-FAM is recovered, and can be monitored at excitation/emission = 490/520 nm. This substrate is employed in the SensoLyte® 520 Renin Assay Kit, cat # AS-72040 from AnaSpec.
MW: 2000 - 2200 Da
%Peak area by HPLC:≥95%
Storage condition: -20°C

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SensoLyte® 520 Neprilysin Activity Assay Kit (Fluorimetric), AnaSpec

Catalog Number: (103010-662)

Supplier: Anaspec Inc

Description: Neprilysin (NEP) is a transmembrane metallopeptidase normally expressed by a variety of tissues

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SensoLyte® 520 IDE Activity Assay Kit (Fluorimetric), AnaSpec

Catalog Number: (103010-678)

Supplier: Anaspec Inc

Description: Insulin degrading enzyme (IDE) is considered a physiological and pathological relevant enzyme

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520 MMP FRET Substrate VI, QXL™ 520-FAM, AnaSpec

Catalog Number: (103003-248)

Supplier: Anaspec Inc

Description: Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This peptides is a sensitive substrate for assaying MMP-2 and 13 activities, Abs/Em = 494/521 nm.
Sequence:QXL™ 520-PLGMWSRK(5-FAM)-NH2
MW:1822.9 Da
% peak area by HPLC:95
Storage condition:-20° C

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SensoLyte® 520 Aggrecanase-1 Assay Kit (Fluorimetric), AnaSpec

Catalog Number: (103010-186)

Supplier: Anaspec Inc

Description: Aggrecanases belong to ADAMTS (A disintegrin and metalloprotease with thrombospondin motif) family of proteases

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7 Dye qPCR Calibration Plate Optimized for ABI7500 Fast 96-Well

Catalog Number: (77463-004)

Supplier: AAT BIOQUEST INC

Description: 7 dye qPCR calibration plate contains seven spectral calibration plates with seven separate dye standards (TAMRA, SYBR, FAM, JOE, NED, ROX, and VIC).