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Supplier: Bachem Americas
Description: This member of the galanin family has been isolated from porcine hypothalamus. It is a 60 amino acid peptide that, unlike galanin, has a non-amidated C-terminus. GALP amino acid residues (9-21) are identical to the biologically active N-terminal (1-13) portion of galanin. Receptor binding studies revealed that GALP had a high affinity for the galanin receptor 2 (GALR2; IC₅₀ = 0.24 nM) and a lower affinity for the GALR1 receptor (IC₅₀ = 4.3 nM). GALP is therefore an endogenous ligand that preferentially binds the GALR2 receptor, whereas galanin is relatively non-selective.

Supplier: Transgenomic
Description: Transgenomic’s ICEme Kit is an in vitro assay that uses multiplexed PCR (MX PCR) followed by multiplexed ICE COLD-PCR (MX-ICP) for amplification and enrichment of mutations in KRAS Exons 2, 3 and 4, NRAS Exons 2, 3 and 4, BRAF Exons 11 and 15, PIK3CA Exons 9 and 20, EGFR Exons 12, 18, 19, 20 and 21.

Catalog Number: (H-3042.0005BA)
Supplier: Bachem Americas
Description: DPDMB, bombesin receptor antagonist with IC₅₀ values for cellular secretion and growth approaching the picomolar region.


Supplier: Cytiva
Description: Acrodisc™ PSF high performance syringe filters can be used for general clarification or application specific uses like dissolution, HPLC, and IC. Engineered to work in most automated filter systems.

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Catalog Number: (10748-250)
Supplier: Prosci
Description: FLIP Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD)- containing adapter molecules and members of the ICE/CED-3 protease family. Caspases-8 (FLICE) and -10 (FLICE2) are two pivotal members in the ICE/CED-3 protease family. FLICE-inhibitory proteins were identified in virus and human and designated v-FLIPs and FLIP, respectively. The human FLIP was also cloned by several labs independently and termed Casper, I-FLICE, FLAME-1, CASH and CLARP3-7. FLIP contains two death effector domains (DEDs) and a caspase-like domain. FLIP interacts with adapter protein FADD and caspase-8 and 10, and potently inhibits apoptosis induced by all known death receptors. Four splice variants of c-FLIPs have been identified and termed FLIPalpha, beta, gamma, and delta, respectively.


Catalog Number: (10749-536)
Supplier: Prosci
Description: Ipaf Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adaptor molecules and proteases including several members of the caspase family. Another family of proteins that functions as a critical regulator of apoptosis and NFkappa signaling pathways is the CED-4/Apaf-1 (apoptosis protein activating factor-1) protein family. Ipaf (ICE protease activating factor) is a CED-4/Apaf-1 family member that activates caspase-1/ICE and can induce apoptosis in human cells in a caspase-1 dependent manner. Ipaf and caspase-1 are thought to interact with each other through the association of the Ipaf amino-terminal CARD (caspase recruitment domain) and amino-terminal CARD of caspase-1.


Catalog Number: (14228-938)
Supplier: Antyila Scientific
Description: Accurately control liquid bath temperature from −40 to 250 °C


Supplier: Thermo Scientific Chemicals
Description: Preparation of cadmium sulfide, as analytical lab reagent, photography, manufacturing of special mirrors, ice-nucleating agent, lubricant, to absorb H2S in sulfide analysis
Supplier: Zymo Research
Description: Water DNase-, RNase-free

Catalog Number: (RC5307-4)
Supplier: Ricca Chemical
Description: 1000 ppm NO3 (KNO3 in water) (non-regulated). For ion chromatography. Clear, colorless. NIST traceable. 120mL.

Catalog Number: (CA80601-214)
Supplier: MilliporeSigma
Description: A nonsteroidal anti-inflammatory drug (NSAID) acts as a reversible and competitive inhibitor of cyclooxygenase 1 (COX-1) (IC₅₀=4.85 µm).

Supplier: ELECTRON MICROSCOPY SCIENCE
Description: QUANTIFOIL® is a carbon film for electron microscopy or low-energy electron point source microscopy.

Catalog Number: (89155-992)
Supplier: Enzo Life Sciences
Description: Synthetic peptides that irreversibly inhibit the activity of each of the caspase-family proteases. YVAD is the recognition sequence for caspase-1/ICE, DEVD is the recognition sequence for caspase-3/CPP32, VEID is the recognition sequence for caspase-6/Mch2, IETD is the recognition sequence for caspase-8/ FLICE, and VAD is the recognition sequence for a caspase(s) that functions upstream of most other caspases.   


Catalog Number: (470330-886)
Supplier: TMW Media Group
Description: How can humans work with the environment?


Supplier: Ricca Chemical
Description: For ion chromatography.
Catalog Number: (77439-294)
Supplier: Bioss
Description: Caspase 9 (also known as ICE like apoptotic protease 6 (ICE LAP6), apoptotic protease Mch6, and apoptotic protease activating factor 3 (Apaf3)) is a member of the peptidase family C14 that contains a CARD domain. This caspase is active as a heterotetramer and has been reported to have two isoforms. ProCaspase 9 has been reported to be approximately 47 kD. This caspase is present in the cytosol and, upon activation, translocates to the mitochondria. Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6. Caspase 9 is inhibited by the dominant negative isoform, BclXL, cIAP1, cIAP2, XIAP, and Livin. This caspase becomes activated when recruited to Apaf1/cytochrome c complex, and following cleavage by Apaf1, granzyme B, Caspase 3, possibly Caspase 8 and Caspase 10 into large p37 and small p10 subunits. Caspase 9 intereacts with BIRC7 and has been shown to cleave PARP and vimentin.?


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