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Catalog Number: (10484-706)
Supplier: Bioss
Description: SNAPC3 is part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. SNAPC3 binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. SNAPC3 recruits TBP and BRF2 to the U6 snRNA TATA box.


Catalog Number: (10484-710)
Supplier: Bioss
Description: SNAPC3 is part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. SNAPC3 binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. SNAPC3 recruits TBP and BRF2 to the U6 snRNA TATA box.


Catalog Number: (10484-962)
Supplier: Bioss
Description: SNAPC3 is part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. SNAPC3 binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. SNAPC3 recruits TBP and BRF2 to the U6 snRNA TATA box.


Supplier: Diagnostic Biosystems
Description: This antibody is specific to an 85 kDa protein known as XRCC1. X-ray repair cross complementing 1 (XRCC1) protein plays a role in excision repair of DNA after ionizing irradiation. XRCC1 binds to DNA ligase III through the C-terminal 96 amino acids and to DNA polymerase β through the N-terminal half. In testis XRCC1 is expressed at high levels.

Catalog Number: (10407-200)
Supplier: Bioss
Description: Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents.ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. Compared with E3 and E4, E2 exhibits the lowest receptor binding affinity. Defects in ApoE are a cause of hyperlipoproteinemia type III due to increased plasma cholesterol and triglycerides levels which are the consequence of impaired clearance of chylomicron and VLDL remnants.Summary: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jul 2008].


Catalog Number: (10407-194)
Supplier: Bioss
Description: Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents.ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. Compared with E3 and E4, E2 exhibits the lowest receptor binding affinity. Defects in ApoE are a cause of hyperlipoproteinemia type III due to increased plasma cholesterol and triglycerides levels which are the consequence of impaired clearance of chylomicron and VLDL remnants.Summary: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jul 2008].


Catalog Number: (CA200063-318)
Supplier: Enzo Life Sciences
Description: Synapsin I, II and III belong to a family of neuron-specific phosphoproteins which maintain a reserve pool of vesicles in the vicinity of the active zone by tethering synaptic vesicles to each other and to an Actin-based cytoskeleton meshwork. They have been shown to regulate neurotransmitter release in mature synapses and to accelerate development of the nervous system.


Supplier: Enzo Life Sciences
Description: Cell permeable peptide that blocks eNOS (NOS III) activity and cellular nitric oxide (NO) release in vitro and reduces inflammation and tumorigenesis in vivo. Caveolin-1 interacts with several lipid-modified signalling ligands, such as EGFR, eNOS, G-protein α-subunits, PKCα, H-Ras, and Src, via the C1-SD82-101 sequence.

Supplier: General Separation Technologies, Inc.
Description: Typical Application: 5% Fragrance Materials Association Mix, Acrylate Impurities II, Antidepressants (Basic Drugs- Uncategories), Antiepileptics, Barbiturates (Acidic/Neutral Drugs-Underivatized), Fentanyls, Organochlorine Pesticides III, Phenoxy Acid Herbicides, Styrene Impurities, TMS derivatized Sugars, Triazine Herbicides I, VOCs in Packaging materials.

Catalog Number: (89360-868)
Supplier: Genetex
Description: CD16 is a 50-65kD cell surface molecule which exists in two forms - a transmembranous form expressed by NK cells and some T cells and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells.


Catalog Number: (470300-280)
Supplier: Ward's Science
Description: CAS Number: 10025-91-9
Formula Weight: 228.11
Formula: SbCl3
Density (g/mL): 3.1
Boiling Point (°C): 223
Freezing Point (°C): 73.4
Solubility: Alcohol, Acetone, Acids, and Reactive with Water
Synonyms: Antimony(III) Chloride
Shelf Life (months): 12
Storage: White

SDS


Catalog Number: (CAPIPA525655)
Supplier: Thermo Scientific
Description: This antibody is predicted to react with bovine, chicken, non-human primate and rat based on sequence homology. Beta III tubulin is abundant in the central and peripheral nervous systems (CNS and PNS) where it is prominently expressed during fetal and postnatal development. As exemplified in cerebellar and sympathoadrenal neurogenesis, the distribution of beta III is neuron-associated, exhibiting distinct temporospatial gradients according to the regional neuroepithelia of origin. However, transient expression of this protein is also present in the subventricular zones of the CNS comprising putative neuronal- and/or glial precursor cells, as well as in Kulchitsky neuroendocrine cells of the fetal respiratory epithelium. This temporally restricted, potentially non-neuronal expression may have implications in the identification of presumptive neurons derived from embryonic stem cells.


Catalog Number: (10088-188)
Supplier: Proteintech
Description: Human increased sodium tolerance-1 (hIST1), encoded by KIAA0174 gene, is a newly reported endosomal sorting complexes required for transport (ESCRT)-III family member. IST1 possesses two different types of microtubule-interacting and transport (MIT) -interacting motifs (MIM1 and MIM2), this is required for its interaction with calpain 7 which is important for their roles in the ESCRT system.


Supplier: General Separation Technologies, Inc.
Description: Typical application: Alcohols II and III, Amines (low MW), Amines/ Alcohols/ Chlorides, Aromatics analysis: ASTM D16 analytes, Aromatics II, Blood alcohol, Bourbon, Branched alcohols, BTEX, Chlorinated Isooctane, Citronella java oil, Esters III, Ethylene oxide, FAME Standard I, FAMEs (Coca Butter), Fast styrene analysis, Flavor volatiles, Formaldehyde Underivatized, Fragrance allergens, Fragrance Reference Standard II, Free Fatty Acids, Free Organic Acids/C4-C5 Isomers, Impurities in Ethylbenzene, Impurities in mixed xylenes, Impurities in p-Xylene-ASTM D3798, Impurities in styrene, Industrial Solvent, Lavender Oil Spiked with Camphor, Monomers in latex paint by headspace, Mushroom aroma (Synthetic), Nitrosamines, Nutmeg oil, Organic acids, Phenols III, Polyunsaturated fatty acid methyl esters, Rapeseed oil, Rapid analysis of water in organic solvents, Solvents I, II, Spearmint oil, Strawberry syrup, Sulphur and Selenium in Garlic by Headspace, Tramanian lavander oil, Volatile organics, Volatile sulfurs.

Catalog Number: (76101-654)
Supplier: Bioss
Description: L glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.


Catalog Number: (76101-656)
Supplier: Bioss
Description: L glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.


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