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Image Unavailable-TCF0106-001G

4-Fluoro-DL-phenylalanine ≥99.0% (by HPLC, titration analysis)

Catalog Number: (TCF0106-001G)
Supplier: TCI America
Description: CAS Number: 51-65-0
MDL Number: MFCD00002600
Molecular Formula: C9H10FNO2
Molecular Weight: 183.18
Purity/Analysis Method: >99.0% (HPLC,T)
Form: Crystal

SDS


Image Unavailable-10349-402

Anti-GGT1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10349-402)
Supplier: Bioss
Description: Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide, cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Isoform 3 seems to be inactive.
Image Unavailable-76083-152

Anti-GGT1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76083-152)
Supplier: Bioss
Description: Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide, cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Isoform 3 seems to be inactive.
Image Unavailable-TCC2579-5G

2-(2-Chlorophenyl)glycine ≥98.0% (by HPLC, titration analysis)

Catalog Number: (TCC2579-5G)
Supplier: TCI America
Description: CAS Number: 88744-36-9
MDL Number: MFCD00049324
Molecular Formula: C8H8ClNO2
Molecular Weight: 185.61
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 186

SDS


Product Image-10087-440

Anti-GCLM Rabbit Polyclonal Antibody

Catalog Number: (10087-440)
Supplier: Proteintech
Description: GCLM(Glutamate--cysteine ligase regulatory subunit) is also named as GLCLR and belongs to the aldo/keto reductase family. It catalyzes the first step of GSH synthesisand is involved in gamma-glutamyl cycle. GCLM is implicated in some forms of hemolytic anemia.
Image Unavailable-10091-022

Anti-NELF Rabbit Polyclonal Antibody

Catalog Number: (10091-022)
Supplier: Proteintech
Description: NSMF, also named as NELF (Nasal embryonic LHRH factor), couples NMDA-sensitive glutamate receptor signaling to the nucleus and triggers long-lasting changes in the cytoarchitecture of dendrites and spine synapse processes. NSMF has some isoforms with MW 44 kDa and 55-60 kDa. This antibody recognizes all the isoforms.
Product Image-89417-072

Anti-HAAO Rabbit Polyclonal Antibody

Catalog Number: (89417-072)
Supplier: Prosci
Description: HAAO Antibody: HAAO (3-Hydroxyanthranilate 3, 4-dioxygenase) is a monomeric cytosolic protein of the family of intramolecular dioxygenases containing non-heme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is present in low amounts in the central nervous system. This enzyme participates in tryptophan metabolism. It employs one cofactor, iron. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurological and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN. Furthermore, recent study shows that HAAO are excellent candidate biomarkers for detecting ovarian cancer.
Product Image-10750-584

Anti-HAAO Rabbit Polyclonal Antibody

Catalog Number: (10750-584)
Supplier: Prosci
Description: HAAO Antibody: HAAO (3-Hydroxyanthranilate 3, 4-dioxygenase) is a monomeric cytosolic protein of the family of intramolecular dioxygenases containing non-heme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is present in low amounts in the central nervous system. This enzyme participates in tryptophan metabolism. It employs one cofactor, iron. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurological and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN. Furthermore, recent study shows that HAAO are excellent candidate biomarkers for detecting ovarian cancer.
Image Unavailable-CA8.19016.0100

(±)-Mandelonitrile for synthesis, Sigma-Aldrich®

Supplier: MilliporeSigma

SDS

Image Unavailable-CAMB-114-0001

Staphylococcus aureus V8 Protease

Catalog Number: (CAMB-114-0001)
Supplier: Rockland Immunochemical
Description: All enzymes and related reagents are configured as an integrated system and have been thoroughly tested.

SDS


Image Unavailable-TCC0017-025G

Sodium (+/-)-10-camphorsulfonate ≥98.0% (by titrimetric analysis)

Catalog Number: (TCC0017-025G)
Supplier: TCI America
Description: CAS Number: 34850-66-3
MDL Number: MFCD00135623
Molecular Formula: C10H16O4S
Molecular Weight: 254.28
Purity/Analysis Method: >98.0% (T)
Form: Crystal

SDS Certificates


Image Unavailable-CAAAH60455-AA

Methyl (±)-lactate 99%

Supplier: Thermo Scientific Chemicals

Certificates

Image Unavailable-10662-816

Anti-GABRB3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10662-816)
Supplier: Bioss
Description: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel..GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct.
Product Image-10751-254

Anti-GLS2 Rabbit Polyclonal Antibody

Catalog Number: (10751-254)
Supplier: Prosci
Description: GLS2 Antibody: Phosphate-activated glutaminase, also known as Glutaminase 2 (GLS2), was initially isolated from rat liver, although it has been shown to be expressed in other tissues. Like the functionally similar, larger kidney glutaminase, GLS2 catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. Expression of GLS2 is increased by p53 under both stressed and nonstressed conditions, resulting in increased levels of glutamate and alpha-ketoglutarate, which in turn results in enhanced mitochondrial respiration and ATP generation. GLS2 also regulates antioxidant defense function in cells by increasing reduced glutathione levels and decreasing ROS-levels, suggesting that GLS2 acts as a mediator of p53's role in antioxidant defense in addition to its role in energy metabolism.
Image Unavailable-N-1555.0005BA

Z-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-Fluoromethylketone

Supplier: Bachem Americas
Description: This specific caspase-3 inhibitor reduces vulnerability to the neuronal death that occurs in the aftermath of kainic acid-evoked status epilepticus (SE).

Product Image-89417-782

Anti-GLS2 Rabbit Polyclonal Antibody

Catalog Number: (89417-782)
Supplier: Prosci
Description: GLS2 Antibody: Phosphate-activated glutaminase, also known as Glutaminase 2 (GLS2), was initially isolated from rat liver, although it has been shown to be expressed in other tissues. Like the functionally similar, larger kidney glutaminase, GLS2 catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. Expression of GLS2 is increased by p53 under both stressed and nonstressed conditions, resulting in increased levels of glutamate and alpha-ketoglutarate, which in turn results in enhanced mitochondrial respiration and ATP generation. GLS2 also regulates antioxidant defense function in cells by increasing reduced glutathione levels and decreasing ROS-levels, suggesting that GLS2 acts as a mediator of p53's role in antioxidant defense in addition to its role in energy metabolism.
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