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Image Unavailable-CAPIPA526743

Anti-CACNA2D3 Rabbit Polyclonal Antibody

Catalog Number: (CAPIPA526743)
Supplier: Thermo Scientific
Description: This antibody is predicted to react with mouse and rat based on sequence homology. CACNA2D3 is a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits.
Product Image-10394-232

Anti-ADCY6 Rabbit Polyclonal Antibody

Catalog Number: (10394-232)
Supplier: Bioss
Description: Membrane-bound, calcium-inhibitable adenylyl cyclase.
Image Unavailable-89156-794

SKF-96365 hydrochloride ≥98% (by HPLC)

Supplier: Enzo Life Sciences
Description: A novel, selective inhibitor of receptor-mediated calcium entry. It inhibits receptor-mediated calcium entry in stimulated platelets (IC50=8-12µM) neutrophils and endothelial cells at concentrations which do not affect internal Ca2+ release. Note, in some cells SK&F 96365 can activate a novel Ca2+ entry pathway. Blocks TRPC3 and TRPC6 activation. Inhibits the histamine-induced formation of nitric oxide in human endothelial cells.

Image Unavailable-10343-708

Anti-LTB4R Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10343-708)
Supplier: Bioss
Description: Receptor for extracellular ATP >UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
Image Unavailable-10343-710

Anti-LTB4R Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10343-710)
Supplier: Bioss
Description: Receptor for extracellular ATP >UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
Image Unavailable-10343-714

Anti-LTB4R Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10343-714)
Supplier: Bioss
Description: Receptor for extracellular ATP >UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
Image Unavailable-76109-686

Anti-EFHD1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76109-686)
Supplier: Bioss
Description: The EF-hand domain is a twelve amino acid loop motif that is commonly found in proteins that participate in calcium-binding events within the cell. EF-hand domains generally exist in a pair that, together, form a stable four-helix bundle that enables the binding of calcium ions. Swiprosin-2, also known as EFHD1 (EF-hand domain-containing protein D1), SWS2, PP3051 or MST133, is a 239 amino acid protein that contains two EF-hand domains and is expressed in a wide variety of tissues, including brain, liver, heart, kidney, testis, ovaries and spleen. Expression of Swiprosin-2, a possible calcium-binding protein, is upregulated during neuronal differentiation, suggesting a role for Swiprosin-2 in brain development and maturation.
Image Unavailable-75789-066

Human Recombinant Grancalcin (from E. coli)

Catalog Number: (75789-066)
Supplier: Prosci
Description: Grancalcin (GCA) is a cytoplasmic granule membrane protein that contains 4 EF-hand domains. GCA is calcium-binding protein and particularly abundant in human neutrophils. GCA is highly expressed in bone marrow, and it can be detected in neutrophils and macrophages. calcium-binding protein GCA cooperates with SRI and LCP1, so it may play a role in the adhesion of neutrophils to fibronectin. GCA also may play a role in the formation of focal adhesions.
Image Unavailable-10399-954

Anti-BNIP3 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10399-954)
Supplier: Bioss
Description: Apoptosis-inducing protein that, which can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2.
Image Unavailable-10399-952

Anti-BNIP3 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10399-952)
Supplier: Bioss
Description: Apoptosis-inducing protein that, which can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2.
Image Unavailable-10464-228

Anti-ATP2A1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10464-228)
Supplier: Bioss
Description: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.
Product Image-10750-270

Anti-CAPN6 Rabbit Polyclonal Antibody

Catalog Number: (10750-270)
Supplier: Prosci
Description: CAPN6 Antibody: Calpains make up a ubiquitously expressed, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. This large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes as their activation can be triggered by calcium influx and oxidative stress. Calpain 6 (CAPN6) is most similar to Calpain 5; the C-terminal region of CAPN6 lacks homology to the calmodulin-like domain of other vertebrate calpains. CAPN6 is thought to be involved in the regulation of microtubule dynamics and cytoskeletal organization. CAPN6 has also been recently identified as an HIV dependency factor (HDF), suggesting that CAPN6 may be an important drug target in HIV treatment.
Product Image-10426-400

Anti-CALR Rabbit Polyclonal Antibody

Catalog Number: (10426-400)
Supplier: Bioss
Description: Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of Calcium homeostasis (By similarity).
Product Image-10103-578

Anti-CACHD1 Rabbit Polyclonal Antibody

Catalog Number: (10103-578)
Supplier: Prosci
Description: CACHD1 belongs to the calcium channel subunit alpha-2/delta family. It contains 2 cache domains and 1 VWFA domain. CACHD1 may regulate voltage-dependent calcium channels.
Product Image-89348-628

Anti-S100 A11 Rabbit Polyclonal Antibody

Catalog Number: (89348-628)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to S100A11 (S100 calcium binding protein A11)
Image Unavailable-89358-084

Anti-NUCB1 Rabbit Polyclonal Antibody

Catalog Number: (89358-084)
Supplier: Genetex
Description: This gene encodes a member of a small calcium-binding EF-hand protein family. The encoded protein is thought to have a key role in Golgi calcium homeostasis and Ca(2+)-regulated signal transduction events. [provided by RefSeq]
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