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Supplier: CYTOART, INC. MS

Description: The mouse monoclonal antibody M19H specifically binds to the scFv region of a CD19-specific mouse monoclonal antibody (mAb, clone FMC63). CD19 antigen is a B-cell specific cell surface antigen, which is expressed in all B-cell lineage malignancies and normal B-cells. The scFv region of FMC63 has been used to develop CD19-specific chimeric antigen receptor (CAR) T cells utilized in clinical trials.

Supplier: CYTOART, INC. MS

Description: The rabbit monoclonal antibody R19M specifically binds to the scFv region of a CD19-specific mouse monoclonal antibody (mAb, clone FMC63). CD19 antigen is a B-cell specific cell surface antigen, which is expressed in all B-cell lineage malignancies and normal B-cells. The scFv region of FMC63 has been used to develop CD19-specific chimeric antigen receptor (CAR) T cells utilized in clinical trials.

Catalog Number: (MSPP-202422)

Supplier: CYTOART, INC. MS

Description: The rabbit monoclonal antibody 1F5 specifically binds to the scFv region of a CD20-specific human monoclonal antibody (mAb, clone 2C6). CD20 (cluster of differentiate 20) is a protein that is expressed on the surface of B cells, starting at the pre-B cell stage and also on mature B cells in the bone marrow and in the periphery. CD20 is not expressed on hematopoietic stem cells, pro-B cells, or normal plasma cells. The scFv region of 2C6 has been used to develop CD20-specific chimeric antigen receptor (CAR) T cells utilized in clinical trials.

Supplier: CYTOART, INC. MS

Description: Ra1D6 specifically binds to the scFv region of a CD19-specific mouse monoclonal antibody (mAb, clone FMC63). CD19 antigen is a B-cell specific cell surface antigen, which is expressed in all B-cell lineage malignancies and normal B-cells. The scFv region of FMC63 has been used to develop CD19- specific chimeric antigen receptor (CAR) T cells utilized in clinical trials.

Supplier: CYTOART, INC. MS

Description: The rabbit monoclonal antibody 1F5 specifically binds to the scFv region of a CD20-specific human monoclonal antibody (mAb, clone 2C6). CD20 (cluster of differentiate 20) is a protein that is expressed on the surface of B cells, starting at the pre-B cell stage and also on mature B cells in the bone marrow and in the periphery. CD20 is not expressed on hematopoietic stem cells, pro-B cells, or normal plasma cells. The scFv region of 2C6 has been used to develop CD20-specific chimeric antigen receptor (CAR) T cells utilized in clinical trials.

Catalog Number: (MSPP-200719)

Supplier: CYTOART, INC. MS

Description: 1A3 specifically binds to the scFv region of a B-cell maturation antigen (BCMA) specific mouse monoclonal antibody (mAb, clone C11D5.3). BCMA is a protein that has been reported to be selectively expressed by B-lineage cells including multiple myeloma cells1 and restrictively expressed in both normal and malignant plasma cells at high levels2. The scFv region of C11D5.3 has been used to develop BCMA-specific chimeric antigen receptor (CAR) T cells utilized in clinical trials.

Supplier: CYTOART, INC. MS

Description: The rabbit monoclonal antibody 1F5 specifically binds to the scFv region of a CD20-specific human monoclonal antibody (mAb, clone 2C6). CD20 (cluster of differentiate 20) is a protein that is expressed on the surface of B cells, starting at the pre-B cell stage and also on mature B cells in the bone marrow and in the periphery. CD20 is not expressed on hematopoietic stem cells, pro-B cells, or normal plasma cells. The scFv region of 2C6 has been used to develop CD20-specific chimeric antigen receptor (CAR) T cells utilized in clinical trials.

Supplier: CYTOART, INC. MS

Description: 1F5-RHC contains a specifically mutated human IgG1 Fc region which results in a reduction in binding to Fc receptors. 1F5-RHC specifically binds to the scFv region of a CD20-specific human monoclonal antibody (mAb, clone 2C6). CD20 (cluster of differentiate 20) is a protein that is expressed on the surface of B cells, starting at the pre-B cell stage and also on mature B cells in the bone marrow and in the periphery. CD20 is not expressed on hematopoietic stem cells, pro-B cells, or normal plasma cells.

New Product

Supplier: CYTOART, INC. MS

Description: The rabbit monoclonal antibody R19M specifically binds to the scFv region of a CD19-specific mouse monoclonal antibody (mAb, clone FMC63). CD19 antigen is a B-cell specific cell surface antigen, which is expressed in all B-cell lineage malignancies and normal B-cells. The scFv region of FMC63 has been used to develop CD19-specific chimeric antigen receptor (CAR) T cells utilized in clinical trials.

New Product

Supplier: CYTOART, INC. MS

Description: The rabbit monoclonal antibody R2L specifically binds to the scFv region of a CD19-specific mouse monoclonal antibody (mAb, clone FMC63). CD19 antigen is a B-cell specific cell surface antigen, which is expressed in all B-cell lineage malignancies and normal B-cells. The scFv region of FMC63 has been used to develop CD19-specific chimeric antigen receptor (CAR) T cells utilized in clinical trials.

Supplier: CYTOART, INC. MS

Description: This antibody reacts with cell membrane-expressed CARs of varying specificity containing a G4S linker within the scFv of the extracellular domain. The poly-Glycine-Serine (G4S) linker is a kind of synthetic peptide linker sequence that is flexible and unstructured. It is frequently used to link the variable heavy (VH) domain and the variable light (VL) domain of single-chain variable fragments (scFvs) and chimeric antigen receptors (CARs) that have an extracellular domain scFv for recognizing target antigens. The linker is made up of a core pentapeptide sequence, Gly-Gly-Gly-Gly-Ser.

New Product

Supplier: CYTOART, INC. MS

Description: The mouse monoclonal antibody M19H specifically binds to the scFv region of a CD19-specific mouse monoclonal antibody (mAb, clone FMC63). CD19 antigen is a B-cell specific cell surface antigen, which is expressed in all B-cell lineage malignancies and normal B-cells. The scFv region of FMC63 has been used to develop CD19-specific chimeric antigen receptor (CAR) T cells utilized in clinical trials.

Catalog Number: (MSPP-200701)

Supplier: CYTOART, INC. MS

Description: 1A3 specifically binds to the scFv region of a B-cell maturation antigen (BCMA) specific mouse monoclonal antibody (mAb, clone C11D5.3). BCMA is a protein that has been reported to be selectively expressed by B-lineage cells including multiple myeloma cells1 and restrictively expressed in both normal and malignant plasma cells at high levels2. The scFv region of C11D5.3 has been used to develop BCMA-specific chimeric antigen receptor (CAR) T cells utilized in clinical trials.

Catalog Number: (MSPP-202719)

Supplier: CYTOART, INC. MS

Description: 1F5-RHC contains a specifically mutated human IgG1 Fc region which results in a reduction in binding to Fc receptors. 1F5-RHC specifically binds to the scFv region of a CD20-specific human monoclonal antibody (mAb, clone 2C6). CD20 (cluster of differentiate 20) is a protein that is expressed on the surface of B cells, starting at the pre-B cell stage and also on mature B cells in the bone marrow and in the periphery. CD20 is not expressed on hematopoietic stem cells, pro-B cells, or normal plasma cells.

Catalog Number: (MSPP-500014)

Supplier: CYTOART, INC. MS

Description: The rabbit polyclonal antibody R19P specifically binds to the scFv region of a CD19-specific mouse monoclonal antibody (mAb, clone FMC63). CD19 antigen is a B-cell specific cell surface antigen, which is expressed in all B-cell lineage malignancies and normal B-cells. The scFv region of FMC63 has been used to develop CD19-specific chimeric antigen receptor (CAR) T cells utilized in clinical trials.

Catalog Number: (MSPP-200705)

Supplier: CYTOART, INC. MS

Description: 1A3 specifically binds to the scFv region of a B-cell maturation antigen (BCMA) specific mouse monoclonal antibody (mAb, clone C11D5.3). BCMA is a protein that has been reported to be selectively expressed by B-lineage cells including multiple myeloma cells1 and restrictively expressed in both normal and malignant plasma cells at high levels2. The scFv region of C11D5.3 has been used to develop BCMA-specific chimeric antigen receptor (CAR) T cells utilized in clinical trials.