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Product Image-CA82022-386

Leupeptin

Catalog Number: (CA82022-386)
Supplier: G-Biosciences
Description: A selection of individual protease inhibitors are offered for researchers who wish to design their own cocktails, supplement existing cocktails, or screen for specific proteases
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5-TMRIA

Catalog Number: (103010-986)
Supplier: Anaspec Inc
Description: Tetramethylrhodamine iodoacetamides (TMRIA) are thiol-selective reactive dyes that are used to label proteins via the cysteine residues. 5-TMRIA, the pure 5-isomer of TMRIA, is increasingly preferred for some particular applications since the mixed isomers of TMRIA may give different results from batch to batch due to the varying ratios and different reactivities of the two isomers. For example, 5-TAMRA is reported to predominantly label SH-1 (Cys-707) of the myosin heavy chain in skinned muscle fibers.
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Human Recombinant CRELD2 (from Cells)

Catalog Number: (75790-070)
Supplier: Prosci
Description: Cysteine-Rich with EGF-Like Domain Protein 2 (CRELD2) is a secreted protein that is a member of the CRELD family. Human CRELD2 is synthesized as a 353 amino acid precursor protein with a signal peptide, a highly conserved domain rich in glutamic acid and tryptophan (WE) and EGF-like repeats. CRELD2 is ubiquitously expressed in many tissues. CRELD2 may interact with CHRNA4 and regulate transport of alpha4- beta 2 neuronal acetylcholine receptor. In addition, CRELD2 could be a novel mediator in regulating the onset and progression of various ER stress-associated diseases.
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SV40 Nuclear Transport Signal Peptide Analog, Bachem

Supplier: Bachem Americas
Description: NLS, cell-penetrating peptide containing 7 amino acids homologous to the SV40 T antigen, was capable of inducing the transport of several carrier proteins to the nucleus. The terminal cysteine permits the attachment of this peptide to any protein using a heterobifunctional crosslinking reagent. Coupling to plasmid DNA has also been realized by M.G.Sebastyén and coworkers. Heterodimerization of TAT and NLS yields an even more effective transfecting peptide.

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Mouse Recombinant RELMalpha (from E. coli)

Supplier: Peprotech
Description: RELMα belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The four known members of this family, resistin, RELMα, RELMβ, and RELMγ, are 85-94 amino acid, secreted proteins sharing a conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELMα and resistin are secreted exclusively by adipocytes, while RELMβ is expressed in the epithelium of the colon and small bowel. The physiological role and molecular targets of RELMα are still unknown. Recombinant Murine RELMα is a 10.0 kDa monomeric protein containing 89 amino acid residues.

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SensoLyte® 520 Calpain Activity Assay Kit (Fluorimetric), AnaSpec

Catalog Number: (103010-504)
Supplier: Anaspec Inc
Description: The calpains are a family of intracellular Ca<sup>2+</sup> dependent cysteine proteases
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SensoLyte® AMC Calpain Activity Assay Kit (Fluorimetric), AnaSpec

Catalog Number: (103010-506)
Supplier: Anaspec Inc
Description: The calpains are a family of intracellular Ca<sup>2+</sup> supdependent cysteine proteases
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Pentagastrin

Supplier: Bachem Americas
Description: Sequence: Boc-β-Ala-Trp-Met-Asp-Phe-NH₂
Synonym(s): AY 6608#ICI 50123#NSC 367746#Boc-(β-Ala¹³)-Gastrin (13-17)#Boc-β-Ala-CCK-4

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SensoLyte® 520 Cathepsin L Assay Kit Fluorimetric, AnaSpec, Inc.

Catalog Number: (103010-644)
Supplier: Anaspec Inc
Description: Cathepsin L, a lysosomal endopeptidase, is a member of the papain-like family of cysteine proteinases
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Human Recombinant RANTES (from E. coli)

Supplier: Peprotech
Description: RANTES is a CC chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant Human RANTES is a 7.8 kDa protein containing 68 amino acid residues, including the four highly conserved cysteine residues present in the CC chemokines. Manufactured using all Animal-Free reagents.

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Mouse Recombinant EG-VEGF (from E. coli)

Supplier: Peprotech
Description: EG-VEGF is a secreted angiogenetic mitogen growth factor expressed in the steroidogenic glands, ovary, testis, adrenal gland, and placenta. EG-VEGF induces proliferation, migration, and fenestration (formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. The murine EG-VEGF gene codes for a 105 amino acid polypeptide containing an N-terminal signal sequence of 19 amino acids. Recombinant Murine EG-VEGF is a 9.6 kDa protein consisting of 86 amino acid residues, including ten cysteine residues that potentially form five pairs of intra-molecular disulfide bonds.

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Human Recombinant MANF (from E. coli)

Supplier: Peprotech
Description: MANF is a secreted neurotrophic factor that is expressed in brain, neuronal and certain non-neuronal tissues. It has been shown to promote the survival, growth and function of dopamine-specific neurons. MANF and its structural homolog CDNF each contain an N-terminal, saposin-like, lipid-binding domain, and a carboxyl-terminal domain that is not homologous to previously characterized protein structures. MANF and CDNF can prevent 6-OHDA-induced degeneration of dopaminergic neurons by triggering survival pathways in a rat experimental model of Parkinson's disease. Recombinant Human MANF is an 18.1 kDa protein consisting of 158 amino acids, including 8 cysteine residues.

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Human Recombinant IL-9 (from E. coli)

Supplier: Peprotech
Description: IL-9 is an immunoregulatory cytokine produced by IL-2 activated Th2 lymphocytes. IL-9 enhances the proliferation of T lymphocytes, mast cells, erythroid precursor cells and megakaryoblastic leukemia cell lines. Over-expression of IL-9 has been implicated in the pathogenesis of anaplastic lymphoma and Hodgkin’s disease. Whereas murine IL-9 can function on human cells, human IL-9 is inactive on mouse cells. Recombinant Human IL-9 is a 14.0 kDa protein of 127 amino acid residues, including 10 cysteine residues that are fully conserved between the human murine proteins.

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Human CYR61 - CCN1 ELISA Kit, Rockland Immunochemicals

Catalog Number: (76235-880)
Supplier: Rockland Immunochemical
Description: Human CYR61 - CCN1 AccuSignal ELISA Kit
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Human Recombinant MDC (from E. coli)

Supplier: Peprotech
Description: MDC is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells, and CD4 T cells. It signals through the CCR4 receptor. MDC chemoattracts monocytes, dendritic cells and NK cells, and exerts HIV-suppressive activity. The 67 amino acid form of MDC displays reduced chemoattractant activity, but retains HIV-suppressive activity. Recombinant Human MDC (CCL22) is an 8.0 kDa protein containing 67 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Image Unavailable-10779-178

Human Recombinant CTGF (from E. coli)

Supplier: Peprotech
Description: CTGF is a member of the CCN family of secreted cysteine-rich regulatory proteins, and is the major mitogenic and chemoattractant protein produced by umbilical vein and vascular endothelial cells. CTGF stimulates the proliferation and differentiation of chondrocytes, induces angiogenesis, promotes cell adhesion of fibroblasts, endothelial and epithelial cells, and binds to IGF, TGF β1 and BMP-4. Cell migration and adhesion are signaled through binding to specific cell surface integrins and to heparin sulfate proteoglycans CTGF (98 a.a.), a lower molecular weight isoform containing the C-terminal portion of the full length CTGF protein, exerts full heparin binding, cell adhesion, and mitogenic CTGF activity. Mature Human CTGF is a 38.0 kDa secreted protein containing 323 amino acid residues. CTGF is comprised of four distinct structural domains (modules), which are identified as IGF binding protein (IGFBP), von Willebrand Factor C (VWFC), thrombospondin type-I (TSP type-I), and C-terminal cysteine knot-like (CTCK) domains. Full length CTGF can be proteolytically cleaved in certain tissues to yield N-terminal truncated isoforms, which, depending on the isoform, contain only the TSP type-I and CTCK domains or contain only the CTCK domain. Recombinant Human CTGF is an 11.0 kDa protein consisting of 97 amino acid residues.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • issued document with your organization's Federal Tax ID Number
  • Government issued document with your organization's Resale Tax ID Number
  • Any other Government ID that includes the business name and address


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