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Catalog Number: (76100-968)
Supplier: Bioss
Description: CaMKI gamma is a Calcium/calmodulin-dependent protein kinase which belongs to a proposed calcium-triggered signaling cascade. In vitro it phosphorylates transcription factor CREB1. It has been proposed that CaMKI gamma is involved in dendritic outgrowth mediated by CaM-dependant protein kinase kinase.


Catalog Number: (89359-672)
Supplier: Genetex
Description: Osteocalcin belongs to the osteocalcin / matrix Gla-protein family and constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.


Catalog Number: (CA11277-358)
Supplier: Mettler Toledo
Description: Membrane Kit, for Calcium ISE, DX series ISE half-cells, Mount the new membrane onto the shaft of your ISE half-cell, Precise determinations, Replaceable membranes for an optimal ion measurement


Supplier: Bachem Americas
Description: This biotinylated ω-conotoxin GVIA is a useful ligand for the characterization of calcium channels.

Catalog Number: (76119-410)
Supplier: Bioss
Description: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.


Catalog Number: (89417-544)
Supplier: Prosci
Description: CaBP8 Antibody: Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP8, contains two EF-hand domains for calcium binding and shares 70% homology with CaBP7 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. Both CaBP8 and CaBP7 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.


Catalog Number: (77180-816)
Supplier: ANTIBODIES.COM LLC
Description: Mouse monoclonal [S100A13/7482] antibody to S100 Calcium Binding Protein A13 / S100A13 for IHC-P with samples derived from Human.


Supplier: MilliporeSigma
Description: Calcimycin (A23187) free acid (from Streptomyces chartreusensis), Calbiochem®
Catalog Number: (10103-934)
Supplier: Prosci
Description: CAPN10 is the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM) and located within the NIDDM1 region. Multiple alternative transcript variants encoding different isoforms have been described for this gene.


Catalog Number: (77437-088)
Supplier: Bioss
Description: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(²⁺) with a low affinity and an EF-hand loop that binds a Ca(²⁺) ion with a high affinity.


Catalog Number: (89318-778)
Supplier: Genetex
Description: Rabbit polyclonal antibody to PPEF1 (protein phosphatase, EF-hand calcium binding domain 1)


Catalog Number: (89355-448)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to CaMKK beta (calcium/calmodulin-dependent protein kinase kinase 2, beta)


Catalog Number: (10167-572)
Supplier: Genetex
Description: Mouse Monoclonal antibody [GT17410] to NDP52 (calcium binding and coiled-coil domain 2)


Catalog Number: (10467-532)
Supplier: Bioss
Description: Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.


Catalog Number: (10375-136)
Supplier: Bioss
Description: Calcium-binding protein. May have a role in calcium homeostasis. Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance (By similarity).


Catalog Number: (89359-676)
Supplier: Genetex
Description: Osteocalcin belongs to the osteocalcin / matrix Gla-protein family and constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.


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