Calcimycin (A23187) Free_acid Streptomyces chartreusensis, Calbiochem®

Supplier: MilliporeSigma

Synonyms: Calcium Ionophore A23187, Calcium Ionophore III, Antibiotic A23187

100105-10MG 100105-1MG 100105-50MG 100105-5MG
CA80055-578EA 562.81 CAD
CA80055-578 CA80055-580 CA80055-582 CA80055-584
Calcimycin (A23187) Free_acid Streptomyces chartreusensis, Calbiochem®
Calcimycin (A23187)

A mobile ion-carrier that forms stable complexes with divalent cations. Useful for increasing intracellular Ca2+ levels. Also acts as an uncoupler of oxidative phosphorylation and inhibitor of mitochondrial ATPase activity. An antibiotic with weak activity against gram-positive bacteria. Also induces apoptosis in mouse lymphoma cell line (S49); however, has been shown to block apoptosis in other systems, such as when interleukin-3 (IL-3) is withdrawn from IL-3-dependent cells.

Formula: C₂₉H₃₇N₃O₆
MW: 523.63 g/mol
MDL Number: MFCD00151202
CAS Number: 52665-69-7

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