Calcimycin (A23187) free acid (from Streptomyces chartreusensis), Calbiochem®

Supplier: MilliporeSigma

100105-10MG 100105-1MG 100105-50MG 100105-5MG

CA80055-578EA 562.81 CAD

CA80055-578 CA80055-580 CA80055-582 CA80055-584

Calcimycin (A23187) free acid (from Streptomyces chartreusensis), Calbiochem®

Calcimycin (A23187)

A mobile ion-carrier that forms stable complexes with divalent cations. Useful for increasing intracellular Ca2+ levels. Also acts as an uncoupler of oxidative phosphorylation and inhibitor of mitochondrial ATPase activity. An antibiotic with weak activity against gram-positive bacteria. Also induces apoptosis in mouse lymphoma cell line (S49); however, has been shown to block apoptosis in other systems, such as when interleukin-3 (IL-3) is withdrawn from IL-3-dependent cells.

Formula: C₂₉H₃₇N₃O₆

MDL Number: MFCD00151202
CAS Number: 52665-69-7

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