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Ammonium chloride ≥99.5% (by argentometric titration), crystals, AR® ACS, Macron Fine Chemicals™

Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Granular.

Certificates

Image Unavailable-89156-794

SKF-96365 hydrochloride ≥98% (by HPLC)

Supplier: Enzo Life Sciences
Description: A novel, selective inhibitor of receptor-mediated calcium entry. It inhibits receptor-mediated calcium entry in stimulated platelets (IC50=8-12µM) neutrophils and endothelial cells at concentrations which do not affect internal Ca2+ release. Note, in some cells SK&F 96365 can activate a novel Ca2+ entry pathway. Blocks TRPC3 and TRPC6 activation. Inhibits the histamine-induced formation of nitric oxide in human endothelial cells.

Image Unavailable-10343-714

Anti-LTB4R Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10343-714)
Supplier: Bioss
Description: Receptor for extracellular ATP >UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
Image Unavailable-10343-708

Anti-LTB4R Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10343-708)
Supplier: Bioss
Description: Receptor for extracellular ATP >UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
Image Unavailable-10343-710

Anti-LTB4R Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10343-710)
Supplier: Bioss
Description: Receptor for extracellular ATP >UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
Image Unavailable-10390-058

Anti-ADCY6 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10390-058)
Supplier: Bioss
Description: Membrane-bound, calcium-inhibitable adenylyl cyclase.
Image Unavailable-76109-008

Anti-IP3 Receptor Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76109-008)
Supplier: Bioss
Description: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
Image Unavailable-76120-936

Anti-KCNIP3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76120-936)
Supplier: Bioss
Description: This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described.
Image Unavailable-76120-934

Anti-KCNIP3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76120-934)
Supplier: Bioss
Description: This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described.
Image Unavailable-75789-066

Human Recombinant Grancalcin (from E. coli)

Catalog Number: (75789-066)
Supplier: Prosci
Description: Grancalcin (GCA) is a cytoplasmic granule membrane protein that contains 4 EF-hand domains. GCA is calcium-binding protein and particularly abundant in human neutrophils. GCA is highly expressed in bone marrow, and it can be detected in neutrophils and macrophages. Calcium-binding protein GCA cooperates with SRI and LCP1, so it may play a role in the adhesion of neutrophils to fibronectin. GCA also may play a role in the formation of focal adhesions.
Image Unavailable-10665-580

Anti-MICU2 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10665-580)
Supplier: Bioss
Description: The EF-hand domain is a twelve amino acid loop motif that is commonly found in proteins that participate in calcium-binding events within the cell. EF-hand domains generally exist in a pair that, together, form a stable four-helix bundle that enables the binding of calcium ions. EF-HA1 (EF-hand domain family, member A1) is a 434 amino acid protein that contains four EF-hand domains, suggesting a role in calcium-mediated events throughout the cell. The gene encoding EF-HA1 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
Image Unavailable-10390-106

Anti-ADCY8 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10390-106)
Supplier: Bioss
Description: This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity).
Image Unavailable-CAAA10425-FI

Ytterbium ≥99.9% (REO, rare earth oxide basis), foil, Thickness: 0.3 mm (0.01 in)

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00011286 Notes: May contain up to 0.15% Calcium

Certificates

Image Unavailable-10368-574

Anti-PTK2B Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10368-574)
Supplier: Bioss
Description: PYK2 is involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. PKY2 may represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage gated potassium channel protein Kv1.2. PYK2 activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity.
Image Unavailable-10368-570

Anti-PTK2B Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10368-570)
Supplier: Bioss
Description: PYK2 is involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. PKY2 may represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage gated potassium channel protein Kv1.2. PYK2 activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity.
Image Unavailable-10665-554

Anti-EFHD1 Rabbit Polyclonal Antibody

Catalog Number: (10665-554)
Supplier: Bioss
Description: The EF-hand domain is a twelve amino acid loop motif that is commonly found in proteins that participate in calcium-binding events within the cell. EF-hand domains generally exist in a pair that, together, form a stable four-helix bundle that enables the binding of calcium ions. Swiprosin-2, also known as EFHD1 (EF-hand domain-containing protein D1), SWS2, PP3051 or MST133, is a 239 amino acid protein that contains two EF-hand domains and is expressed in a wide variety of tissues, including brain, liver, heart, kidney, testis, ovaries and spleen. Expression of Swiprosin-2, a possible calcium-binding protein, is upregulated during neuronal differentiation, suggesting a role for Swiprosin-2 in brain development and maturation.
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