You Searched For: Physics+Educational+Materials

Catalog Number: (10664-978)

Supplier: Bioss

Description: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).

Catalog Number: (10375-148)

Supplier: Bioss

Description: Calcium-binding protein. May have a role in calcium homeostasis. Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance (By similarity).

Catalog Number: (CA282-49)

Supplier: Hach

Description: For pH adjustment in calcium determination by EDTA titration

SDS

Catalog Number: (CA1.11110.0001)

Supplier: MilliporeSigma

SDS Certificates

Catalog Number: (10665-616)

Supplier: Bioss

Description: The EF-hand domain is a twelve amino acid loop motif that is commonly found in proteins that participate in calcium-binding events within the cell. EF-hand domains generally exist in a pair that, together, form a stable four-helix bundle that enables the binding of calcium ions. Swiprosin-2, also known as EFHD1 (EF-hand domain-containing protein D1), SWS2, PP3051 or MST133, is a 239 amino acid protein that contains two EF-hand domains and is expressed in a wide variety of tissues, including brain, liver, heart, kidney, testis, ovaries and spleen. Expression of Swiprosin-2, a possible calcium-binding protein, is upregulated during neuronal differentiation, suggesting a role for Swiprosin-2 in brain development and maturation.

Catalog Number: (10390-060)

Supplier: Bioss

Description: Membrane-bound, calcium-inhibitable adenylyl cyclase.

Catalog Number: (CA1.00049.0001)

Supplier: MilliporeSigma

SDS

Catalog Number: (10068-602)

Supplier: Prosci

Description: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca2+ with a low affinity and an EF-hand loop that binds a Ca2+ ion with a high affinity.

Supplier: Thermo Scientific Chemicals

Description: Irreversibly inhibits calcium-independent phospholipase A-2

Certificates

Catalog Number: (77437-450)

Supplier: Bioss

Description: PLA2G4E is a calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position.

Catalog Number: (76098-946)

Supplier: Bioss

Description: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.

Catalog Number: (77438-682)

Supplier: Bioss

Description: May be involved in the regulation of calcium transport.

Catalog Number: (77664-082)

Supplier: WORLD PRECISION INSTRUMENTS LLC

Description: CALBUF-2 is especially suitable for calibrating fluorescent Ca⁺⁺ indicators. It provides eleven buffer standards in the 10⁻⁴ to 10⁻⁸ M Ca⁺⁺ range, whereas other commonly used fluorescent Ca⁺⁺ indicators have the apparent Kd in the range of 100 to 300 nM. As with any ionic sensitive indicator, the sensitivity range of these indicators is about 1.0 log unit above and below the Kd. CALBUF-2 provides seven calibration points in this sensitivity range. It has an osmolarity of 0.305, which is isotonic with most mammalian cells.

New Product

Catalog Number: (10343-716)

Supplier: Bioss

Description: Receptor for extracellular ATP >UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.

Catalog Number: (76333-998)

Supplier: Biosensis

Description: Visinin (sometimes known as hippocalcin-like protein 3, HLP3, HPCAL3, HUVISL1, VLP-1, VILIP and VILIP-1) was originally isolated biochemically from chicken retina as a major protein of about 24kDa on SDS-PAGE (1). Following cloning and sequencing of visinin, several visinin like proteins were discovered by homology screening (2, 3). One of these, Visinin-like protein 1 is a small Calcium binding protein which is very abundant in the nervous system and is found only in neurons, though different neurons have different levels of expression (4, 5). It is particularly concentrated in cerebellar Purkinje cells, and tends to be most abundant in perikarya and dendrites. The protein belongs to the large superfamly of calmodulin and paravalbumin type proteins which function by binding Calcium ions. Calcium binding alters the confomation of these proteins and allow them to interact with other binding partners, the properties of which they may alter. Visinin-like protein 1 has four "EF hand" domains, which are negatively charged helix-turn-helix peptides which are responsible for Calcium binding. Visinin-like protein 1 is 191 amino acids in size and has a molecular weight on SDS-PAGE of 22kDa. The protein has recently been suggested to be a useful biomarker of Alzheimer's disease and traumatic brain injury (6, 7, 8).

Catalog Number: (10343-696)

Supplier: Bioss

Description: Receptor for extracellular ATP >UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.