You Searched For: CL-82198+(MMP-13+inhibitor)


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Supplier: VWR International
Description: This durable VWR® polypropylene lab chair features antimicrobial properties and UV inhibitors integrated in its seat and backrest, and the ergonomic functionality and versatility to make it an ideal choice for a variety of laboratory types and applications.

Catalog Number: (CA82603-220)
Supplier: MilliporeSigma
Description: p38 MAP Kinase Inhibitor VIII ≥97% (by HPLC), Calbiochem®, Sigma-Aldrich®

Catalog Number: (76446-858)
Supplier: VWR International
Description: Ideal for all PCR protocols, these 0.1 and 0.2 ml tubes and caps are made from polypropylene and are compatible with most popular thermal cycler blocks.


Supplier: VWR International
Description: Clear liquid. Contains cyclohexene as a preservative.
Catalog Number: (10403-610)
Supplier: Bioss
Description: May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.


Catalog Number: (10403-608)
Supplier: Bioss
Description: May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.


Catalog Number: (BDH67009.400)
Supplier: VWR International
Description: 1,2,4-Trichlorobenzene ≥99.0%, HiPerSolv CHROMANORM® for HPLC, VWR Chemicals BDH®

Catalog Number: (10403-612)
Supplier: Bioss
Description: May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.


Catalog Number: (76078-906)
Supplier: Bioss
Description: May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.


Catalog Number: (10403-616)
Supplier: Bioss
Description: May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.


Supplier: Enzo Life Sciences
Description: Small molecule STAT3-specific inhibitor which blocks activation, dimerization and nuclear translocation via binding to the STAT3 SH2 domain. It is a very useful tool for exploring STAT3-mediated signaling pathways. It blocks LPS-mediated STAT3 tyrosine phosphorylation which leads to inhibition of LPS-mediated IL-1β and IL-6 production. In primary cultures of rat neural stem cells it blocks IL-15-induced differentiation.

Catalog Number: (76101-228)
Supplier: Bioss
Description: Matrix Metalloproteinase 8 (MMP8) is also known as neutrophil collagenase and collagenase 2. MMP8 degrades fibrillar collagens types I, II, III, aggrecan, serpins and alpha 2 macroglobulin. All collagenases cleave fibrillar collagens at one specific site resulting in generation of N terminal three quarter and C terminal one quarter fragments, which then denature to gelatin at body temperature. The substrate specificity of collagenases is variable: MMP1 degrades type III collagen more efficiently than type I or type II collagen, whereas MMP8 is more potent in degrading type I collagen than type III or type II collagen. MMP13, in turn degrades type II collagen 6 fold more efficiently than type I and type II collagens and displays almost 50 fold stronger gelatinolytic activity than MMP1 and MMP8. MMP8 is very similar to MMP1, sharing 57 % amino acid identity. Most cell types do not produce MMP8. Until recently, it was thought that MMP8 was produced exclusively by neutrophils, but it has also been detected in other cell types including arthritic chondrocytes and gingival fibroblasts. The human MMP8 gene has the chromosomal location of 11q22.2-22.3. MMP8 is heavily glycosylated, and the zymogen has a mass of 85 Kd. The zymogen is quickly activated to the 64 Kd form, and this breaks down to a cascade of active forms.


Supplier: Thermo Scientific Chemicals
Description: ITIC-Cl, 3,9-bis(2-methylene-((3-(1,1-dicyanomethylene)-6,7-dichloro)-indanone))-5,5,11,11-tetrakis(4-hexylphenyl)-dithieno[2,3-d:2,3-d]-s-indaceno[1,2-b:5,6-b]dithiophene, Formula: C94H78Cl4O2S4, Formula Weight: 1565.72, Storage and Sensitivity: Ambient temperatures, Size: 500mg

Catalog Number: (BDH85441.601)
Supplier: VWR International
Description: A ready-to-use kit that fits into your lab coat pocket.

Catalog Number: (10403-614)
Supplier: Bioss
Description: May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.


Catalog Number: (CA80051-248)
Supplier: MilliporeSigma
Description: Set contains 1mg samples of three caspase inhibitors: Caspase-3 Inhibitor II, Z-DEVD-FMK (80051-378), Caspase-1 Inhibitor I, Ac-YVAD-CHO (80052-266), and Caspase-1 Inhibitor V, Z-VAD-FMK (80054-792)


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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