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Image Unavailable-89351-754

Anti-MMP9 Rabbit Polyclonal Antibody

Catalog Number: (89351-754)
Supplier: Genetex
Description: MMPs (Matrix Metalloproteinases) are proteolytic enzymes capable of degrading connective tissue components. MMPs play a crucial role in tumor cell invasion and metastasis.
Product Image-10105-156

Anti-MMP19 Rabbit Polyclonal Antibody

Catalog Number: (10105-156)
Supplier: Prosci
Description: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling. They are also involved in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The function of the protein encoded by this gene has not been determined. This gene was previously referred to as MMP18 but has been renamed matrix metalloproteinase 19 (MMP19). Multiple transcript variants encoding distict isoforms have been identified for this gene.
Image Unavailable-CAPIPA5-13179

Anti-MMP10 Rabbit Polyclonal Antibody

Catalog Number: (CAPIPA5-13179)
Supplier: Thermo Scientific
Description: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP10 degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Image Unavailable-M-1895.0001BA

Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH₂ Trifluoroacetate

Supplier: Bachem Americas
Description: Mca-PLGL-Dpa-AR-amide is a very sensitive FRET substrate for continuous assays and in situ determination of the matrix metalloproteinase activity. Cleavage at the Gly-Leu bond separates the highly fluorescent Mca group from the efficient 2,4-dinitrophenyl quencher, resulting in an increase in fluorescence intensity. The kcat/Km values for the punctuated metalloproteinase (MMP-7) and for gelatinase (MMP-2), e.g., are 1.7·10⁵ and 6.3·10⁵ M⁻¹s⁻¹, respectively.

Product Image-77048-936

Anti-MMP11 Rabbit Polyclonal Antibody

Catalog Number: (77048-936)
Supplier: ANTIBODIES.COM LLC
Description: Rabbit polyclonal antibody to MMP-11 for WB, IHC, IF and ELISA with samples derived from Human, Mouse and Rat.
Image Unavailable-102885-306

Anti-MMP16 Mouse Monoclonal Antibody [clone: 782005]

Catalog Number: (102885-306)
Supplier: R&D Systems
Description: Human MMP-16/MT3-MMP Monoclonal antibody (Clone 782005), Isotype: Mouse IgG2A, Immunogen: Chinese hamster ovary cell line CHO-derived recombinant, Application: Flow Cytometry, 100 UG
Image Unavailable-103005-950

580 MMP FRET Substrate I, QXL™ 570-TAMRA, AnaSpec

Catalog Number: (103005-950)
Supplier: Anaspec Inc
Description: Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
With the higher emission wavelength, this substrate is ideal for use in experiments where the test compounds might have strong autofluorescence at shorter wavelength, Abs/Em = 547/574 nm.
Sequence:QXL™ 570-KPLA-Nva-Dap(5-TAMRA)-AR-NH2
MW:1768 Da
% peak area by HPLC:95
Storage condition:-20° C
Product Image-89164-536

Human Recombinant MMP-19 (Catalytic Domain)

Catalog Number: (89164-536)
Supplier: Enzo Life Sciences
Description: Produced in E.coli.
Image Unavailable-102979-992

Anti-COL1 Rabbit Polyclonal Antibody

Catalog Number: (102979-992)
Supplier: Adipogen
Description: The proteolysis of collagens plays an important role in numerous physiological and pathological situations such as morphogenesis, wound healing, arthritis, arteriosclerosis and tumor metastasis. Triple helical type I collagens are made up of two alpha1 (I) and one alpha2 (I) chains, and are found in skin, tendon, ligament and interstitial tissues. Due to their fibrillary structure native collagens are resistant to most proteases. They are substrates for certain matrix metalloproteinases (MMPs), which constitute a family of zinc-dependent enzymes catalyzing the degradation of extracellular matrix components. Initial MMP-8 dependent cleavage of collagen into the characteristic ¾ and ¼ fragments has been shown to enable MMP-9 diffusion along the protein helix with preferential binding to the collagen ¾ fragment tail. Finally, untwisting of the helix end results in the local denaturation of the triple helical structure.
Product Image-77070-814

Anti-MMP15 Rabbit Polyclonal Antibody

Catalog Number: (77070-814)
Supplier: ANTIBODIES.COM LLC
Description: Rabbit polyclonal antibody to MMP-15 for WB and ELISA with samples derived from Human and Mouse.
Image Unavailable-76078-914

Anti-MMP-2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76078-914)
Supplier: Bioss
Description: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14. PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels. Isoform 2: Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways.
Product Image-77050-996

Anti-MMP16 Rabbit Polyclonal Antibody

Catalog Number: (77050-996)
Supplier: ANTIBODIES.COM LLC
Description: Rabbit polyclonal antibody to MMP-16 for WB, IHC and ELISA with samples derived from Human, Mouse and Rat.
Product Image-77051-900

Anti-MMP7 Rabbit Polyclonal Antibody

Catalog Number: (77051-900)
Supplier: ANTIBODIES.COM LLC
Description: Rabbit polyclonal antibody to MMP-7 for WB, IHC and ELISA with samples derived from Human, Mouse and Rat.
Product Image-10103-188

Anti-MMP23B Rabbit Polyclonal Antibody

Catalog Number: (10103-188)
Supplier: Prosci
Description: MMP23B is a protease.This gene (MMP23B) encodes a member of the matrix metalloproteinase (MMP) family, and it is part of a duplicated region of chromosome 1p36.3. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. This gene belongs to the more telomeric copy of the duplicated region.
Image Unavailable-77663-962

Piconozzle Gaskets

Supplier: WORLD PRECISION INSTRUMENTS LLC
Description: Package of 10 single size gaskets for use with the PV820, PV830, MMP, and DMP.

New Product

Image Unavailable-89143-926

Human MMP-1 proenzyme (from Fibroblasts)

Catalog Number: (89143-926)
Supplier: Enzo Life Sciences
Description: Isolated from human rheumatoid synovial fibroblasts. Requires activation.
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