You Searched For: CL-82198+(MMP-13+inhibitor)


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Catalog Number: (10425-280)
Supplier: Bioss
Description: ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration.A member of the metalloproteinase family containing disintegrin like domains (ADAMs), the function of ADAMTS8 is still poorly understood. ADAMTS8 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, and has been shown to be proteolytically active on a range of substrates. ADAMTS8 is inhibited by the endogenous MMP inhibitors, TIMP1, 2, 3 and 4, but most efficiently by TIMP3. In addition to the metalloprotease domain, ADAMTS8 has a propeptide domain, a Prohormone Convertase (PC, furin) cleavage site, a cysteine rich domain and thrombospondin 1 like domains.


Catalog Number: (76078-622)
Supplier: Bioss
Description: ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration.A member of the metalloproteinase family containing disintegrin like domains (ADAMs), the function of ADAMTS8 is still poorly understood. ADAMTS8 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, and has been shown to be proteolytically active on a range of substrates. ADAMTS8 is inhibited by the endogenous MMP inhibitors, TIMP1, 2, 3 and 4, but most efficiently by TIMP3. In addition to the metalloprotease domain, ADAMTS8 has a propeptide domain, a Prohormone Convertase (PC, furin) cleavage site, a cysteine rich domain and thrombospondin 1 like domains.


Catalog Number: (10425-278)
Supplier: Bioss
Description: ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration.A member of the metalloproteinase family containing disintegrin like domains (ADAMs), the function of ADAMTS8 is still poorly understood. ADAMTS8 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, and has been shown to be proteolytically active on a range of substrates. ADAMTS8 is inhibited by the endogenous MMP inhibitors, TIMP1, 2, 3 and 4, but most efficiently by TIMP3. In addition to the metalloprotease domain, ADAMTS8 has a propeptide domain, a Prohormone Convertase (PC, furin) cleavage site, a cysteine rich domain and thrombospondin 1 like domains.


Catalog Number: (89162-506)
Supplier: Enzo Life Sciences
Description: Prostanoid receptor inhibitor


Catalog Number: (89157-632)
Supplier: Enzo Life Sciences
Description: GST inhibitor


Catalog Number: (89149-016)
Supplier: Enzo Life Sciences
Description: Na+/K+- and Mg2+-ATPase inhibitor


Catalog Number: (89150-780)
Supplier: Enzo Life Sciences
Description: Inhibitor of caspase-3 and caspase-7 binding to an allosteric site and not to the active site.


Catalog Number: (89160-846)
Supplier: Enzo Life Sciences
Description: Inhibitor of dopamine and norepinephrine transporters


Catalog Number: (89158-988)
Supplier: Enzo Life Sciences
Description: HDAC inhibitor


Catalog Number: (89160-856)
Supplier: Enzo Life Sciences
Description: Serotonin transporter inhibitor


Catalog Number: (89150-508)
Supplier: Enzo Life Sciences
Description: Cell cycle inhibitor


Catalog Number: (89146-632)
Supplier: Enzo Life Sciences
Description: Caspase inhibitor


Supplier: Enzo Life Sciences
Description: PARP inhibitor

Catalog Number: (CA80016-856)
Supplier: MilliporeSigma
Description: Akti-1/2; 1,3-Dihydro-1-(1-((4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one

Catalog Number: (89161-746)
Supplier: Enzo Life Sciences
Description: Calcineurin inhibitor


Supplier: Thermo Scientific Chemicals
Description: A serotonin uptake inhibitor
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