BERTIN CORP

Anti-PNMT Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: Converts noradrenaline to adrenaline.

Catalog Number: 10389-840

Supplier: Bioss

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Anti-PNMT Rabbit Polyclonal Antibody (Cy7®)

Description: Converts noradrenaline to adrenaline.

Catalog Number: 10389-836

Supplier: Bioss

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Anti-PNMT Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: Converts noradrenaline to adrenaline.

Catalog Number: 76085-330

Supplier: Bioss

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Anti-PNMT Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: Converts noradrenaline to adrenaline.

Catalog Number: 76085-328

Supplier: Bioss

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Wallcur® PRACTI-Ampules

Description: Prefilled And Etched For Proper Breakage.

Catalog Number: 470358-280

Supplier: WALLCUR, LLC.

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Wallcur® PRACTI-Code Meds

Description: Preloaded Syringes For Your EMS, ACLS Or Nursing Training

Catalog Number: 470358-272

Supplier: WALLCUR, LLC.

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Anti-LNC1 Mouse Monoclonal Antibody [clone: LNC 1; LNC1;LNC-1]

Description: Tyrosine hydroxylase is an excellent marker for dopaminergic and noradrenergic neurons. Tyrosine hydroxylase (a.k.a. tyrosine 3-monooxygenase) is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to L-3,4-dihydroxyphenylalanine (L-DOPA). L-DOPA is a precursor for dopamine, which, in turn, is a precursor for the important neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline). Tyrosine hydroxylase catalyzes the rate limiting step in this synthesis of catecholamines. In humans, tyrosine hydroxylase is encoded by the TH gene, and the enzyme is present in the central nervous system (CNS), peripheral symphatic neurons and the adrenal medulla. The enzymatic activity of TH requires ferrous ions as cofactors and is believed to be regulated by phosphorylation. At least four isoforms of human TH have been identified which result from alternative splicing. Tyrosine hydroxylase, phenylalanine hydroxylase and tryptophan hydroxylase together make up the family of aromatic amino acid hydroxylases (AAAHs). http://en.wikipedia.org/wiki/Tyrosine_hydroxylase

Catalog Number: 10782-104

Supplier: Biosensis

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Anti-NET1 Rabbit Polyclonal Antibody

Description: Catecholamine, a term used for the hormone adrenaline and its sequentially hydroxylated form noradrenaline, is involved in fight or flight responses. Noradrenaline is released from the post ganglionic sympathetic nerve endings and exerts its effects locally in the immediate vicinity of its release. In the CNS, noradrenaline is involved in a number of physiological responses including mood, sleep regulation, alertness and arousal, both cognitive and non-cognitive expression of behaviors, and control of the endocrine and autonomic nervous systems. Peripherally, noradrenaline is present in sympathetic nerve endings and has full control of the sympathetic nervous system. Noradrenaline released from pre-synaptic nerve terminals is reabsorbed (70-90%) by noradrenaline transporters and its biological effects are terminated. The noradrenaline transport via noradrenaline transporters is an active, Na+/Cl- dependent transport process mediated by noradrenaline transporters. Noradrenaline transporters constitute the primary mechanism for inactivation of synaptically released noradrenaline, are targets for multiple antidepressants and psychostimulants, and are deficient in affective and autonomic disorders. In rat brain, noradrenaline transporter is expressed in noradrenergic neuronal somata, axons and dendrites, and hippocampus and cortex, but is absent from epinephrine- and dopamine-containing neurons. At least 13 genetic variations have been reported in the noradrenaline transporter protein that affect noradrenaline re-uptake and concentrations in cerebrospinal fluid in humans. The association between these genetic variations in noradrenaline transporters and several psychiatric and cardiovascular disorders is just emerging. Recently, a single amino acid mutation (hNET-A457P) showed deficiency in noradrenaline transport in an orthostatic intolerance patient.

Catalog Number: 10435-430

Supplier: Bioss

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