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Anti-CD40 Armenian Hamster Monoclonal Antibody [clone: HM40-3]

Catalog Number: (75842-776)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The HM40-3 antibody blocks the binding of CD40L (CD154) and stimulates B and dendritic cell proliferation.
Image Unavailable-75842-810

Anti-CD11a Rat Monoclonal Antibody [clone: M17/4]

Catalog Number: (75842-810)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The M17/4 monoclonal antibody specifically reacts with mouse CD11a, a 180kDA glycoprotein. CD11a is the integrin alpha L chain that forms with CD18 the heterodimer molecule Lymphocyte Function-associated Antigen-1 (LFA-1). LFA-1 is expressed on all leukocytes and is involved in intercellular adhesions. The M17/4 antibody blocks many of the LFA-1 mediated cell interaction and in vivo it prolongs allograft survival, inhibits the autoimmune response, and reduces graft versus host reactions.
Image Unavailable-75843-550

Anti-TER-119 Rat Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: TER-119]

Catalog Number: (75843-550)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The TER-119 monoclonal antibody specifically binds to the mouse 52 kDa Glycophorin A expressed on the erythroid lineage cells, from the early proerythroblast to mature erythrocyte stages, in the fetal liver, adult bone marrow, newborn liver, yolk sac, and adult lymphoid organs. The TER-119 antibody is used, together with other antibodies, as a marker for hematopoietic lineages cells.
Image Unavailable-75843-496

Anti-IFNG Mouse Monoclonal Antibody [clone: NIB42]

Catalog Number: (75843-496)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The NIB42 monoclonal antibody specifically reacts with human interferon gamma, a multifunctional cytokine that is produced mainly by activated T and NK cells. Interferon gamma has anti-viral and anti-parasitic properties and plays an important role in the activation, growth, and differentiation of macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-α, to inhibit proliferation of normal and transformed cells. The NIB42 antibody neutralizes IFN-γ.
Image Unavailable-75843-610

Anti-Ly-6A/E Rat Monoclonal Antibody (PE (Phycoerythrin)-Cy7®) [clone: D7]

Catalog Number: (75843-610)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The D7 monoclonal antibody specifically reacts with mouse Ly-6A/E (Sca-1), a 18 kDa GPI-linked surface protein. It is expressed on multipotent hematopoietic stem cells (HSC) and subsets of B and T cells and involved in B and T cell lymphocyte responses. Splenocytes from Ly-6.2 strains exhibit a larger number of D7-positive cells than those from the Ly-6.1 strains.
Image Unavailable-75843-790

Anti-CD2 Mouse Monoclonal Antibody (APC (Allophycocyanin)) [clone: RPA-2.10]

Catalog Number: (75843-790)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The RPA-2.10 monoclonal antibody specifically binds to human CD2, a 50 kDA type I transmembrane glycoprotein. CD2 is expressed on NK cells, thymocytes, T lymphocytes, and B cell subsets. CD2 is involved in cell-cell adhesion, T cell activation, and T cell signaling. Its ligand is CD58 and it is reported to bind to CD48, CD59, and CD15. The RPA-2.10 antibody is reported to be cross-reactive with pigs and non-human primates.
Image Unavailable-75843-816

Anti-SELP Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: AK-4]

Catalog Number: (75843-816)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The AK-4 monoclonal antibody specifically reacts with human CD62P (P-Selectin), a 140 kDA type I transmembrane glycoprotein also known as platelet activation-dependent granule membrane protein (PADGEM). Upon activation it is quickly transported to the plasma membrane from the alpha-granules of platelets and WEibel-Palade bodies of endothelial cells. It is essential to the functions of cell adhesion during inflammatory reactions and in the interaction of platelets with monocytes and neutrophils.
Image Unavailable-75844-414

Anti-CD146 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: P1H12]

Catalog Number: (75844-414)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The P1H12 monoclonal antibody reacts with CD146, 118kDA transmembrane glycoprotein that is also called the melanoma cell adhesion molecule (Mel-CAM), MUC18, Endo-CAM, and S-Endo. It is a prominently glycosylated protein with carbohydrates comprising the majority of its mass and it is expressed on melanoma, stromal, endothelial, and bone marrow fibroblasts. The P1H12 antibody cross reacts with human, mouse, canine, rabbit to the exclusion of rat protein.
Image Unavailable-75843-096

Anti-CD69 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: FN50]

Catalog Number: (75843-096)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The FN50 monoclonal antibody specifically reacts with human CD69, the 27-33 kDA type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM). It is expressed as a disulfide-linked dimer on B cells, T cells, NK cells, platelets, eosinophils, and neutrophils. It increases in expression upon cell activation and seems to serve a role as a signaling receptor.
Image Unavailable-75843-082

Anti-CD8b Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: H35-17.2]

Catalog Number: (75843-082)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The H35-17.2 monoclonal antibody specifically reacts the mouse cd8 beta, a 32 kDa chain also known as Ly-3 and Lyt-3. CD8 is a T cell surface antigen co-receptor that interacts with MHC class I molecules on antigen presenting cells. It is expressed as a heterodimer with the alpha cd8 chain. The H35-17.2 antibody blocks T cell-mediated cytolysis of allogeneic lymphoma cells.
Image Unavailable-75841-708

Anti-CD3 Mouse Monoclonal Antibody [clone: OKT3]

Catalog Number: (75841-708)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The OKT3 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.The OKT3 antibody is an immunosuppressive, which has proven to be an effective therapeutic agent in liver, heart, and renal allograft rejection.
Image Unavailable-75841-700

Anti-CD3 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: G4.18]

Catalog Number: (75841-700)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The G4.18 monoclonal antibody specifically reacts with rat CD3, a T cell lineage marker and associated with the T cell receptor (TCR). CD3 is involved in antigen recognition, cell activation, and signal transduction and is found on subsets of NK-T, peripheral T, dendritic epidermal T, and thymocyte cells. Immobilized G4.18 antibody activates T cells in vitro and in vivo treatments of the G4.18 antibody prevents cardiac and skin allograft rejection.
Image Unavailable-75841-746

Anti-CD14 Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: 61D3]

Catalog Number: (75841-746)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The 61D3 monoclonal antibody specifically reacts with CD14, a cell surface anchored glycoprotein that is primarily expressed on monocytes, inerfollicular macrophages, and a subset of dendritic cells. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-kappaB.
Image Unavailable-75841-764

Anti-CD14 Rat Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: Sa2-8]

Catalog Number: (75841-764)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The Sa2-8 monoclonal antibody specifically reacts with mouse CD14, a cell surface anchored glycoprotein that is primarily expressed on macrophages and is secreted in certain conditions. CD14 associates with LPS and LBP to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The Sa2-8 antibody exhibits a weak antagonistic activate in relation to TNF alpha production and NF-kappa B activation.
Image Unavailable-75841-760

Anti-CD14 Mouse Monoclonal Antibody (APC (Allophycocyanin)) [clone: 61D3]

Catalog Number: (75841-760)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The 61D3 monoclonal antibody specifically reacts with CD14, a cell surface anchored glycoprotein that is primarily expressed on monocytes, inerfollicular macrophages, and a subset of dendritic cells. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-kappaB.
Image Unavailable-75841-748

Anti-CD14 Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: 61D3]

Catalog Number: (75841-748)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The 61D3 monoclonal antibody specifically reacts with CD14, a cell surface anchored glycoprotein that is primarily expressed on monocytes, inerfollicular macrophages, and a subset of dendritic cells. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-kappaB.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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