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Geography Tutor Video Series

Supplier: TMW Media Group

Description: Sharpen basic geography skills.

Anti-VANGL2 Goat Polyclonal Antibody

Catalog Number: (CAPIPA5-18654)

Supplier: Thermo Scientific

Description: This antibody is predicted to react with bovine and zebrafish based on sequence homology. Planar cell polarity is the term given to global cell polarization, such as the alignment of mammalian body hair along the anterior-posterior axis or the orientation of steriocilia bundles in the inner ear. VANGL2 is a PCP protein that is involved in the transmission of directional cues to align either individual cells within an epithelial sheet or multicellular clusters, which polarize as a group .

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Anti-CKBB Rabbit Polyclonal Antibody

Catalog Number: (CAPIPA5-13811)

Supplier: Thermo Scientific

Description: Creatine Kinase (CK) is a dimeric enzyme composed of either M- or B-type subunits. The resulting isoenzymes are expressed at varying levels in different tissues. CK-BB, a cytoplasmic predominantly found in brain tissues, participates in energy homeostasis, reversibly catalyzing the transfer of a phosphate group between ATP and target proteins such as a creatine phosphate. CK-BB exists in normally neglible amounts in the serum of adults, overexpression of CK-BB is associated with cancers of the breast, ovary, prostate, colon, and in small-cell lung cancer. Global assessment of changes in serum levels of CK-BB, CK-MB and CK-MM, are used as a marker for myocardial infarction.

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Big City® Polyethylene Liners, 2 mil, Berry Plastics

Supplier: Tyco

Description: For heavy-duty uses.

Anti-NR5A1 Rabbit Polyclonal Antibody

Catalog Number: (10091-284)

Supplier: Proteintech

Description: Steroidogenic factor-1 (SF-1,STF-1), also known as NR5A1, regulates multiple genes involved in the adrenal and gonadal development and in the biosynthesis of a variety of hormones, including adrenal and gonadal steroids, anti-Mullerian hormone (AMH), and gonadotropins. SF-1 belongs to the fushi tarazu factor-1 (FTZ-F1) subfamily of orphan nuclear receptors. Initially identified as a tissue-specific transcriptional regulator of cytochrome P450 steroid hydroxylases, research studies of both global and tissue-specific knockout mice have demonstrated that SF-1 is required for the development of adrenal glands, gonads, ventromedial hypothalamus, and for the proper functioning of pituitary gonadotropes. Indeed, humans with mutations that render SF-1 transcriptionally inactive can present with testicular failure, ovarian failure, and adrenal insufficiency. Furthermore, dysregulation of SF-1 has been linked to diseases such as endometriosis and adrenocortical carcinoma.Like other nuclear hormone receptors, SF-1 has a modular domain structure composed of an N-terminal zinc finger DNA-binding domain, a ligand-binding domain, a C-terminal AF-2 activation domain, and a hinge region with AF-1-like activation activity. SF-1 also contains a fushi tarazu factor 1 box, which functions as an accessory DNA binding domain. SF-1 is primarily phosphorylated at Ser203, which is thought to enhance its transcriptional activity by promoting complex formation with transcriptional cofactors. In addition to phosphorylation at Ser203, SF-1 is subject to SUMO conjugation and acetylation at ε-amino groups of target lysine residues. Whereas SUMOylation represses SF-1 function, acetylation enhances its transcriptional activity.In the adult ovary, SF-1 localizes to theca/interstitial cells.

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Global Scientific and Environmental Issues Video Series

Supplier: TMW Media Group

Description: How do humans impact the environment?

Global Footprints On The Environment Video Series

Supplier: TMW Media Group

Description: How can we work with the environment?

Show Me Science: Advanced Video Series

Supplier: TMW Media Group

Description: More advanced topics in science.

Accessories for OptiTherm® Reaction Blocks, Round Bottom, Chemglass

Catalog Number: (89166-618)

Supplier: Chemglass

Description: Anodized Berry Aluminum, OptiTherm (for use with block OPT1000)

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Miraculin (1-20)

Supplier: Bachem Americas

Description: The eicosapeptide DSAPNPVLDIDGEKLRTGTN corresponds to the N-terminal sequence of the taste-modifying 191 amino acid-containing protein miraculin produced by the berries of Richadella dulcifica.