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Product Image-10782-628

Anti-rh CNTF Sheep Polyclonal Antibody

Catalog Number: (10782-628)
Supplier: Biosensis
Description: CNTF is a survival promoting factor for different types of neurons in vitro and in vivo. The essential structural features for the biological function of human CNTF were investigated by Thier, M. et al. They showed that deletion of 14 N-terminal and 18 C-terminal amino acids significantly increased bioactivity compared to wild-type CNTF. FUNCTION: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. SUBUNIT: Homodimer. SUBCELLULAR LOCATION: Cytoplasm. TISSUE SPECIFICITY: Nervous system. PHARMACEUTICAL: CNTF is being tested under the name Axokine by Regeneron Pharmaceuticals for treatment of human motor neuron diseases, such as amyotrophic lateral sclerosis (ALS). As it induces substantial weight loss, preferentially of fat as opposed to lean body mass, it is being used for obesity treatment. SIMILARITY: Belongs to the CNTF family.
Product Image-10017-922

KIMBLE® KIMAX® Pink Colorware Erlenmeyer Flasks, DWK Life Sciences

Supplier: DWK Life Sciences (KIMBLE)
Description: Please join us to support breast cancer prevention, treatment, and research by purchasing Pink Colorware from DWK Life Sciences.

Image Unavailable-H-4075.0005BA

(D-Trp⁶)-LHRH Acetate

Supplier: Bachem Americas
Description: LHRH is also called Gonadotropin-Releasing Hormone (GnRH) or Luteinizing Hormone-Releasing Factor (LRF).

Product Image-470136-466

Clinical Diagnosis of Diabetes Kit

Catalog Number: (470136-466)
Supplier: Edvotek
Description: Over 380 million people worldwide are afflicted by diabetes mellitus, a chronic disease that leads to high blood sugar. Due to genetic predisposition and high-calorie, low-activity lifestyles, that number continues to grow. Without early detection and treatment of diabetes, severe medical complications can occur. In this simulation, students will diagnose diabetes in three patients using the urine glucose test and Enzyme-linked Immunosorbent Assay (ELISA).
Image Unavailable-H-4060.0005BA

(Des-Gly¹⁰,D-Leu⁶,Pro-NHEt⁹)-LHRH Acetate

Supplier: Bachem Americas
Description: LHRH is also called Gonadotropin-Releasing Hormone (GnRH) or Luteinizing Hormone-Releasing Factor (LRF).

Product Image-CA89500-750

Surface Water Test Kit, Hach

Catalog Number: (CA89500-750)
Supplier: Hach
Description: The ideal tool for source water monitoring and wastewater treatment plants, this kit uses drop count titration and color disc methods to provide economical, easy-to-use tests for ammonia, chlorine, pH, nitrate, dissolved oxygen, phosphorus, and temperature

SDS


Product Image-10103-838

Anti-P2RY1 Rabbit Polyclonal Antibody

Catalog Number: (10103-838)
Supplier: Prosci
Description: P2RY12 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders.The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene.
Product Image-89417-324

Anti-ESX1 Rabbit Polyclonal Antibody

Catalog Number: (89417-324)
Supplier: Prosci
Description: ESX1 Antibody: Homeobox proteins are transcription factors that contain a helix-turn-helix DNA binding domain termed the homeodomain. ESX1 is an X-linked homeobox gene primarily expressed in the placenta and testis and contains two functional domains: the homeodomain and the proline-rich domain. During embryogenesis, ESX1 is expressed in the extraembryonic tissues, including the endoderm of the visceral yolk sac, the ectoderm of the chorion and the labyrinthine trophoblast of the chorioallantoic placenta. ESX1 can act like a transcriptional repressor to the human oncogene K-ras and treatment of human cancer cells with an ESX1 protein fragment containing the homeodomain reduces the tumorgenicity of cells containing oncogenic K-ras mutations, suggesting ESX1 may be useful as a therapeutic treatment for these cancers.
Image Unavailable-103006-912

Histone H3 (1-21), Biotin

Catalog Number: (103006-912)
Supplier: Anaspec Inc
Description: This sequence corresponds to the first 21 amino acids of the NH2 terminal of histone H3 followed by a GG linker and a biotinylated lysine. This peptide was used to investigate the characteristics and mechanisms of ethanol-induced histone H3 acetylation in rat hepatocytes. Immunocytochemical and immunoblot analyses revealed that ethanol treatment significantly increased H3 acetylation at Lys9 with negligible effects at Lys14, 18, and 23.
Sequence:ARTKQTARKSTGGKAPRKQLA-GGK(Biotin)-NH2
MW:2723.2 Da
% peak area by HPLC:95
Storage condition:-20° C
Product Image-CA89500-664

Model CY-3 Cyanuric Acid Test Kit, Hach

Catalog Number: (CA89500-664)
Supplier: Hach
Description: A stabilizing agent for chlorine, cyanuric acid is used in swimming pool treatment

SDS


Product Image-CA89500-668

Tannin/Lignin Test Kit, Hach

Supplier: Hach
Description: A product of decomposed plant material, tannin occurs in natural waters and is used for boiler and cooling tower water treatment, dyeing, ink manufacture, tanning, and paper sizing

SDS

Product Image-EPSCA-SV2-2

EP Scientific Silanized Culture Tubes and Vials, Thermo Scientific

Supplier: Thermo Scientific
Description: Ready-to-use, disposable glassware is ideal for trace organic analysis and storage of materials prone to adhering to glass.

Image Unavailable-75810-698

Benzoic acid ≥99.5%, crystals USP, Ph. Eur., BP, JP

Catalog Number: (75810-698)
Supplier: Spectrum Chemicals
Description: BENZOIC ACID, CRYSTAL, USP, EP, BP, JP an aromatic crystalline solid that is colorless. It is used for medical purposes as a component of Whitfield's ointment, a treatment of fungal skin diseases, and can be used as a topical antiseptic. Spectrum Chemical USP products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
Product Image-10750-876

Anti-MAEL Rabbit Polyclonal Antibody

Catalog Number: (10750-876)
Supplier: Prosci
Description: Maelstrom Antibody: The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.
Image Unavailable-77007-500

Anti-Pertuzumab Mouse Monoclonal Antibody [clone: 11H4]

Catalog Number: (77007-500)
Supplier: Genscript
Description: Pertuzumab (also called 2C4, trade name Perjeta) is a monoclonal antibody used in combination with trastuzumab and docetaxel for the treatment of metastatic HER2-positive breast cancer; it also used in the same combination as a neoadjuvant in early HER2-positive breast cancer. The epitope for pertuzumab is the domain of HER2 where it binds to HER3, and pertuzumab prevents the HER2/HER3 dimer from forming, which blocks signalling by the dimer to prevent HER2 from functioning. Anti-Pertuzumab antibody (11H4), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Pertuzumab.
Product Image-89417-032

Anti-MC4R Rabbit Polyclonal Antibody

Catalog Number: (89417-032)
Supplier: Prosci
Description: MC4R Antibody: The melanocortin-4 receptor (MC4R) is a member of the superfamily of seven transmembrane G-protein coupled receptors that are involved in multiple signal transduction pathways including the cAMP and MAPK signaling pathways. It is thought that the melanocortin system modulates energy expenditure and insulin sensitivity; activation of the MC4R results in the inhibition of c-Jun N-terminal kinase (JNK) activity and promotes insulin signaling. MC4R-null mice display maturity onset obesity characterized by hyperphagia, increased adiposity, hyperinsulinaemia and hyperleptinaemia, suggesting that like other obesity-linked genes such as FTO, PTER, and NPC1, MC4R is a potential candidate target for the treatment of obesity.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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