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Image Unavailable-CAPIPA5-18005

Anti-RACGAP1 Goat Polyclonal Antibody

Catalog Number: (CAPIPA5-18005)
Supplier: Thermo Scientific
Description: This antibody is predicted to react with bovine and canine based on sequence homology. Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.
Image Unavailable-10469-336

Anti-RACGAP1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10469-336)
Supplier: Bioss
Description: Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.
Image Unavailable-76119-722

Anti-RACGAP1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76119-722)
Supplier: Bioss
Description: Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.
Image Unavailable-76119-726

Anti-RACGAP1 Ser387 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76119-726)
Supplier: Bioss
Description: Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.
Product Image-10104-098

Anti-ARHGEF25 Rabbit Polyclonal Antibody

Catalog Number: (10104-098)
Supplier: Prosci
Description: The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange.The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange (Souchet et al., 2002 [PubMed 11861769]).
Product Image-89355-402

Anti-ROCK2 Rabbit Polyclonal Antibody

Catalog Number: (89355-402)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to ROCK2 (rho-associated protein kinase 2)
Image Unavailable-10462-582

Anti-ARHGEF18 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10462-582)
Supplier: Bioss
Description: Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008].
Image Unavailable-10366-774

Anti-PPP1R12A Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10366-774)
Supplier: Bioss
Description: Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate(GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. Rho-associated kinase (Rho-kinase), which is activated by GTP. RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase. Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC. Thus, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Product Image-77522-548

Rat ARHGEF7 (Rho Guanine Nucleotide Exchange Factor 7) ELISA Kit

Catalog Number: (77522-548)
Supplier: AFG Bioscience
Description: Rat ARHGEF7 (Rho Guanine Nucleotide Exchange Factor 7) ELISA Kit

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Product Image-10110-944

Anti-ARHGAP28 Rabbit Polyclonal Antibody

Catalog Number: (10110-944)
Supplier: Prosci
Description: ARHGAP28 contains 1 Rho-GAP domain. ARHGAP28 is a GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Image Unavailable-76083-796

Anti-MYPT1 Ser507 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76083-796)
Supplier: Bioss
Description: Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate(GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. Rho-associated kinase (Rho-kinase), which is activated by GTP. RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase. Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC. Thus, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase. Several transcript variants encoding different isoforms have been found for this gene.
Image Unavailable-10366-778

Anti-PPP1R12A Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10366-778)
Supplier: Bioss
Description: Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate(GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. Rho-associated kinase (Rho-kinase), which is activated by GTP. RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase. Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC. Thus, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Image Unavailable-10366-780

Anti-PPP1R12A Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10366-780)
Supplier: Bioss
Description: Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate(GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. Rho-associated kinase (Rho-kinase), which is activated by GTP. RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase. Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC. Thus, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Image Unavailable-76101-744

Anti-GEF H1 Ser886 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76101-744)
Supplier: Bioss
Description: GEF-H1 is a Rho guanine nucleotide exchange factor that localizes to microtubules and regulates Rho activity in response to microtubule destabilization (loss of interaction between GEF-H1 and microtubules leads to activation of Rho). This protein has also been shown to localize to tight junctions and modulate polarized cell permeability.
Product Image-77393-078

HighSpec Rho Starter Set 2: HighSpec Rho1D4 MagBeads + Rho1D4 Peptide

Catalog Number: (77393-078)
Supplier: CUBE BIOTECH
Description: The Rho1D4 starters set 2 combines our HighSpec Rho1D4 MagBeads and the Rho1D4 elution peptide.
Image Unavailable-10326-410

Anti-ARHGEF2 Rabbit Polyclonal Antibody

Catalog Number: (10326-410)
Supplier: Bioss
Description: GEF-H1 is a Rho guanine nucleotide exchange factor that localizes to microtubules and regulates Rho activity in response to microtubule destabilization (loss of interaction between GEF-H1 and microtubules leads to activation of Rho). This protein has also been shown to localize to tight junctions and modulate polarized cell permeability.
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