You Searched For: 5-Carboxy-2-chlorophenylboronic+acid


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Catalog Number: (89420-994)
Supplier: Prosci
Description: NUMB peptide is used for blocking the activity of NUMB antibody.


Catalog Number: (89420-488)
Supplier: Prosci
Description: LZTR2 pepide is used for blocking the activity of LZTR2 antibody.


Catalog Number: (89420-570)
Supplier: Prosci
Description: APC3 peptide is used for blocking the activity of APC3 antibody.


Catalog Number: (89420-578)
Supplier: Prosci
Description: APC7 peptide is used for blocking the activity of APC7 antibody.


Catalog Number: (89420-472)
Supplier: Prosci
Description: KLF4 pepide is used for blocking the activity of KLF4 antibody.


Catalog Number: (89420-474)
Supplier: Prosci
Description: Lin28 pepide is used for blocking the activity of Lin28 antibody.


Catalog Number: (89421-120)
Supplier: Prosci
Description: TGM5 peptide is used for blocking the activity of TGM5 antibody.


Catalog Number: (89419-184)
Supplier: Prosci
Description: Beta-actin peptide is used for blocking the activity of beta-actin antibody.


Catalog Number: (89417-036)
Supplier: Prosci
Description: UCMA Antibody: UCMA is a secreted cartilage-specific protein that was discovered in a screen for differentially expressed genes in retinoic acid-treated mouse chondrocytes. It was also identified in a human chondrocyte EST screen for candidate genes of skeletal dysplasias. UCMA expression is thought to parallel that of collagen II with its expression decreasing with maturation chrondrocytes mature. UCMA is processed by a furin-like protease into two fragments, an amino-terminal fragment and a carboxy-terminal fragment (UCMA-C). Application of recombinant UCMA-C to primary osteoblasts, mesenchymal stem cells, and MC3T3-E1 pre-osteoblasts interferes with their osteogenic differentiation, but does not affect expression of chondrocyte-specific genes or chondrocyte proliferation, suggesting that UCMA may be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells. At least two isoforms of UCMA are known to exist.


Catalog Number: (89418-802)
Supplier: Prosci
Description: XAF-1 peptide is used for blocking the activity of XAF-1 antibody.


Catalog Number: (89420-922)
Supplier: Prosci
Description: CTTNBL1 peptide is used for blocking the activity of CTNNBL1 antibody.


Catalog Number: (10354-366)
Supplier: Bioss
Description: HDAC7 is a member of the class II mammalian histone deacetylases, which plays an important role in modulating the eukaryotic chromatin structure. Human HDAC7 is composed of 912 amino acid residues. Although HDAC7 is localized mostly to the cell nucleus, it is also found in the cytoplasm, suggesting nucleo-cytoplasmic shuttling. The histone deacetylase activity of HDAC7 maps to a carboxy-terminal domain and is dependent on interaction with class I HDACs in the nucleus. It is an active component of different transcriptional corepressor complexes that can be recruited to specific promoter regions via interactions with a growing number of sequence specific transcriptional factors. HDAC7 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, leading to the inhibition of gene transcription.


Catalog Number: (89367-328)
Supplier: Genetex
Description: Cyclic nucleotides are hydrolyzed and compartmentalized by a family of enzymes called phosphodieterases. In mammals at least 11 different families of PDEs can be discriminated (PDE1-11) based on their kinetic properties and inhibition to various pharmacological agents. Three different PDE1 genes have been identified (PDE1A, B, and C). PDE1A and PDE1B have higher affinity for cGMP than for cAMP, whereas PDE1C has high affinity for both cAMP and cGMP. The PDE1A gene family includes various proteins that differ from each other at amino and carboxy termini of the protein. There are three novel PDE1A variants so far identified (PDE1A1; PDE1A3 and PD1A5), PDE1A5 encodes a 519 residue protein , which is different from PDE1A1 by insertion of 14 amino acid residues at the carboxy terminal and is also different from PDE1A3 by a divergent at N-terminus. The tissue distribution of PDE1A is different from other PDE1 gene family members. In testis PDE1A is highly expressed but in different stages of developing germ cells.


Catalog Number: (89418-788)
Supplier: Prosci
Description: CARMA2 peptide is used for blocking the activity of CARMA2 antibody.


Supplier: TCI America
Description: CAS Number: 399-76-8
MDL Number: MFCD00005612
Molecular Formula: C9H6FNO2
Molecular Weight: 179.15
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 249

SDS

Catalog Number: (89415-466)
Supplier: Prosci
Description: Smac Antibody: The inhibitor of apoptosis proteins (IAPs) regulate programmed cell death by inhibiting members of the caspase family of enzymes. A novel mammalian protein that binds to IAPs and neutralizes the inhibitory effect of IAPs on caspases was recently identified and designated Smac/DIABLO. Smac/DIABLO is a mitochondrial protein that is released along with cytochrome c during apoptosis and activates cytochrome c/Apaf-1/capase-9 pathway. Analysis of the structural basis of Smac/DIABLO reveals that the N-terminal amino acids are required for binding of Smac/DIABLO to IAPs and activation of caspases. Smac/DIABLO is expressed in a variety of human and mouse tissues.


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