You Searched For: 4-Carboxymethyl-6,7-methylenedioxycoumarin


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Catalog Number: (CA407603-BL)
Supplier: Biolegend
Description: Biotin anti-rat IgG2c [MRG2c-67]; Isotype: Mouse IgG; Reactivity: Rat; Apps: ELISA, FC; Size: 50 μg


Supplier: Tonbo Biosciences
Description: The 53-6.7 antibody reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor in antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

Catalog Number: (77127-716)
Supplier: Prosci
Description: Anti-Cd8a Rat Monoclonal Antibody [clone: [53-6.7]] (FITC (Fluorescein Isothiocyanate))


Catalog Number: (76761-516)
Supplier: Prosci
Description: Anti-Cd8a Rat Monoclonal Antibody [clone: [53-6.7]] (PE (Phycoerythrin)-Cy7®)


Supplier: MilliporeSigma
Description: Cas Number 9005-67-8, For Synthesis
Supplier: TCI America
Description: CAS Number: 9004-67-5 MDL Number: MFCD00081763 Form: Crystal Color: White

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Catalog Number: (ABCA_AB25294-50UG)
Supplier: Abcam
Description: PE/Texas Red® Rat monoclonal [53-6.7] to CD8 alpha.

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Supplier: Biolegend
Description: APC anti-mouse CD8a [53-6.7]; Isotype: Rat IgG2a, κ; Reactivity: Mouse; Apps: FC; Size: 100 μg

Catalog Number: (75844-244)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The 53-6.7 monoclonal antibody specifically reacts with Ly-2, the 38 kDa alpha chain, and with Lyt-2, the 34 kDa alpha’ chain, of the mouse CD8 antigen. The alpha’ chain is the truncated form of alpha chain, encoded by the same CD8a gene. In CD8a, the alpha and alpha’ chains form heterodimers with CD8b (the beta chains) or homodimers (alpha-alpha), which occur as receptors on the surface of the majority of thymocytes. A subpopulation of mature T lymphocytes expresses the CD8 alpha beta (alpha beta TCR T cells), and a subpopulation of intestinal intraepithelial lymphocytes and dendritic cells express CD8a without CD8b.CD8 interacts with the mouse major histocompatibility complex class I (MHC class I) molecules on antigen-presenting cells or epithelial cells. Its function seems to be to attenuate the CD8-mediated signal for the stimulation of intrathymic T-cell maturation.The 53-6.7 antibody is useful for depleting CD8+ peripheral T lymphocytes. It cross reacts with the alpha- and alpha’-like polypeptides on some thymic and peripheral lymphocytes.


Catalog Number: (CA1.08390.0250)
Supplier: MilliporeSigma
Description: C14H23N3O10, Cas no 67-43-6, Hazard Causes serious eye irritation.

Catalog Number: (75836-622)
Supplier: BURKLE INC
Description: The SteriPlast® spoon ideal for food, animal feed and pharmaceutical industries.


Supplier: Tonbo Biosciences
Description: The 53-6.7 antibody reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor in antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

Supplier: TCI America
Description: CAS Number: 9004-67-5 MDL Number: MFCD00081763 Form: Crystal Color: White
Supplier: TCI America
Description: CAS Number: 9004-67-5 MDL Number: MFCD00081763 Form: Crystal Color: White
Catalog Number: (CA1.03590.0010)
Supplier: MilliporeSigma
Description: Grade Acs, Cas Number 6152-67-6


Catalog Number: (75843-054)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The 53-6.7 monoclonal antibody specifically reacts with Ly-2, the 38 kDa alpha chain, and with Lyt-2, the 34 kDa alpha’ chain, of the mouse CD8 antigen. The alpha’ chain is the truncated form of alpha chain, encoded by the same CD8a gene. In CD8a, the alpha and alpha’ chains form heterodimers with CD8b (the beta chains) or homodimers (alpha-alpha), which occur as receptors on the surface of the majority of thymocytes. A subpopulation of mature T lymphocytes expresses the CD8 alpha beta (alpha beta TCR T cells), and a subpopulation of intestinal intraepithelial lymphocytes and dendritic cells express CD8a without CD8b. CD8 interacts with the mouse major histocompatibility complex class I (MHC class I) molecules on antigen-presenting cells or epithelial cells. Its function seems to be to attenuate the CD8-mediated signal for the stimulation of intrathymic T-cell maturation.The 53-6.7 antibody is useful for depleting CD8+ peripheral T lymphocytes. It cross reacts with the alpha- and alpha’-like polypeptides on some thymic and peripheral lymphocytes.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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