You Searched For: 3-Chloro-2-nitrobenzoic+acid

Catalog Number: (76262-880)

Supplier: Rockland Immunochemical

Description: The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR Associated (Cas) system was discovered in bacteria as a defense against foreign DNA, even being believed to act as a sort of prokaryotic immune system. The Cas9 protein is becoming a a useful tool in the field of genomic editing for its ability to induce site-directed double strand breaks in DNA. It can cleave almost any sequence complementary to the guide RNA and has recently been used for modifying the genome of human embryos for the first time.

Catalog Number: (76262-926)

Supplier: Rockland Immunochemical

Description: ALPHA-1-ANTI-TRYPSIN Antibody is specific for alpha-1-anti-trypsin. Alpha 1-Antitrypsin or α1-antitrypsin (A1AT) is a protease inhibitor belonging to the serpin superfamily and is generally known as serum trypsin inhibitor. Alpha-1-anti-trypsin protects tissues from enzymes of inflammatory cells. A1AT antibody is suitbale for immunology and cardiovascular researcher.

Catalog Number: (76262-952)

Supplier: Rockland Immunochemical

Description: Anti-Ezh1 Antibody was designed, produced, and validated as part of the Joy Cappel Young Investigator Award (JCYIA). Anti-EZH1 Antibody detects human EZH1. Polycomb group (PcG) proteins are essential epigenetic regulators in normal tissue homeostasis and are involved in transcriptional repression. The PcG members Ezh2 and Ezh1 are important determinants of embryonic stem cell identity, and the transcript levels of these histone methyltransferases are inversely correlated during development. Recent studies have shown that EZH1 also has histone H3K27 methyltransferase activity and binds to an overlapping subset of genes. EZH1 and EZH2 have different expression patterns. EZH2 is found in actively proliferating cells, whereas EZH1 expression is higher in nonproliferative adult tissues. EZH1 partially compensates for the loss of EZH2, as shown in cells lacking only Ezh2. In mice, EZH1 is a regulator of homeotic gene expression implicated in the assembly of repressive protein complexes in chromatin. Anti-EZH1 Antibody is ideal for investigators studying pathogenesis of hematological malignancies.

Catalog Number: (76262-942)

Supplier: Rockland Immunochemical

Description: Anti-Nrf-2 antibody was designed, produced, and validated as part of the Joy Cappel Young Investigator Award (JCYIA). Nrf2 links the transcriptional modulation of key metabolic genes to cellular growth and development and has been implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. Nrf2 is localized in the cytoplasm and nucleus and ubiquitously expressed with the highest concentrations in the kidney, muscle, lung, heart, liver, and brain. Anti-Nrf2 antibody is useful for researchers interested in cellular growth, transcription factor, and cancer research.

Catalog Number: (10801-350)

Supplier: Rockland Immunochemical

Description: This product is designed for immunofluorescence microscopy, fluorescence based plate assays (FLISA) and fluorescent western blotting. This product is also suitable for multiplex analysis, including multicolor imaging, utilizing various commercial platforms.

Catalog Number: (10801-358)

Supplier: Rockland Immunochemical

Description: FGF13(Fibroblast growth factor 13), also called FHF2 is a protein that in humans is encoded by the FGF13 gene.The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF13is a large gene, extending over approximately 200 kb in Xq26.3, and contains at least 7 exons. By cytogenetic, FISH, and database analysis, Gecz et al. (1999) localized the FGF13 gene within a 400-kb duplication interval on chromosome Xq26.3. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. Other areas of interests and use for researchers include cancer, borjeson-forssman-lehmann syndrome, regulation of actin cytoskeleton pathways, apoptosis, GPCR pathways, TGF-Beta pathways, and Rho familty GTPase pathways. This gene is located to a region associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a syndromal X-linked mental retardation, which suggests it may be a candidate gene for familial cases of the BFL syndrome. The function of this gene has not yet been determined. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.

Catalog Number: (RL619-102-002)

Supplier: Rockland Immunochemical

Description: Anti-Armenian Hamster Igg (Handl) (Goat) Antibody Fluorescein Conjugated - 619-102-002 Armenian Hamster Igg (Handl) Antibody Fluorescein Conjugated 1 Mg

Supplier: Rockland Immunochemical

Description: CYTOCHROME p450, Polyclonal antibody, Host: Rabbit, Species: Human, Isotype: IgG, Immunogen: sequence shows 83, Synonyms: Rabbit Anti-Cytochrome p450 Antibody, Rabbit Anti-CYP1A1 Antibody, CYPIA1, Cytochrome P450 form 6, Size: 25 uL

Catalog Number: (76221-838)

Supplier: Rockland Immunochemical

Description: Hemoglobin C Control Peptide

Catalog Number: (76225-996)

Supplier: Rockland Immunochemical

Description: Anti-Mouse IgG DyLight800 Antibody generated in rabbit detects reactivity to Mouse IgG1, IgG2a, IgG2b and IgG3. Secreted as part of the adaptive immune response by plasma B cells, immunoglobulin G constitutes 75% of serum immunoglobulins. Immunoglobulin G binds to viruses, bacteria, as well as fungi and facilitates their destruction or neutralization via agglutination (and thereby immobilizing them), activation of the compliment cascade, and opsinization for phagocytosis. The whole IgG molecule possesses both the F(c) region, recognized by high-affinity Fc receptor proteins, as well as the F(ab) region possessing the epitope-recognition site. IgG1, IgG2a, IgG2b and IgG3 chains of the antibody molecule are present. Secondary Antibodies are available in a variety of formats and conjugate types. When choosing a secondary antibody product, consideration must be given to species and immunoglobulin specificity, conjugate type, fragment and chain specificity, level of cross-reactivity, and host-species source and fragment composition.

Catalog Number: (76262-726)

Supplier: Rockland Immunochemical

Description: Anti-HSF1 Antibody was designed, produced, and validated as part of the Joy Cappel Young Investigator Award (JCYIA). Heat shock factor 1 (HSF1) is a highly conserved transcription factor that coordinates stress-induced transcription and directs versatile physiological processes in eukaryotes. Upon stress, HSF1 is the key transcriptional activator of chaperones, co-chaperones and ubiquitin, and also coordinates the expression of many transcriptional and translational regulators, signaling molecules and mitotic determinants. HSF1 is involved in balancing core cellular processes during stress and enables their rapid re-establishment once conditions suitable for proliferation have been restored. Importantly, HSF1 controls a distinct set of target genes in cell stress, development and cancer progression. The central role of HSF1 in diverse cellular functions is reflected in pathologies, such as neurodegenerative diseases and cancer, where an imbalance in HSF1 activity facilitates disease onset. The ability of cancer cells to harness HSF1 for metastatic progression highlights the plasticity of HSF1 in rewiring transcription and coordinating cellular processes. Anti-HSF1 antibody is thus ideal for investigators involved in cancer research and neurodegenerative diseases.

Catalog Number: (RL200-341-268)

Supplier: Rockland Immunochemical

Description: This monoclonal antibody is suitable for immunofluorescence microscopy, FLISA and western blotting. Expect a band approximately 56 kDa in size corresponding to phosphorylated AKT Protein by western blotting in the appropriate cell lysate or extract.

Catalog Number: (RL210-406-B68)

Supplier: Rockland Immunochemical

Description: This Protein-A purified, MBP-cross-adsorbed antibody is suitable for ELISA and western blotting of mouse and human NAG-1 Protein.  For detection of NAG-1 in mouse serum, a sandwich ELISA is suggested using this antibody in combination with anti-NAG-1/GDF1.

Catalog Number: (RL200-346-382)

Supplier: Rockland Immunochemical

Description: 100ug. Clone: 33D10.D2. Immunogen: This antibody was produced in mice by repeated immunizations with 6X His epitope tag peptide H-H-H-H-H-H conjugated to KLH using maleimide.

Supplier: Rockland Immunochemical

Description: This monoclonal antibody is suitable for ELISA, immunochemistry and western blotting. Expect a band approximately 106 kDa in size corresponding to TRPC6 Protein by western blotting in the appropriate cell lysate or extract.

Catalog Number: (RL209-403-B32)

Supplier: Rockland Immunochemical

Description: This purified antibody has been tested for use in ELISA and western blotting. By western blot a band approximately 30.3 kDa in size corresponding to human IL17-A Protein is expected in the appropriate cell lysate or extract.