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Human Endo-4A-Glu-Tetracosactide Trifluoroacetate

Supplier: Bachem Americas
Description: Please see also α-MSH (corresponds to acetyl-ACTH (1-13) amide, H-1075), α-MSH (free acid) (acetyl-ACTH (1-13), H-1070), and (Des-acetyl)-α-MSH (H-4390). Wied: Pituitary Adrenal System Hormones and Behaviour. Symposium on Developments in Endocrinology (1976) / Anon.: ACTH and Related Peptides: Structure, Regulation, and Action. Ann. N.Y. Acad. Sci. 297, 1 (1977) / A.V.Schally: Aspects of Hypothalamic Regulation of the Pituitary Gland. Science 202, 18 (1978) / R.Schwyzer: Studies on Polypeptide Receptors. A Critical View on the Mechanism of ACTH Action. Bull. Schweiz. Acad. Med. Wiss. 34, 263 (1978).

Image Unavailable-76098-260

Anti-C3Orf34 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76098-260)
Supplier: Bioss
Description: C3orf34 (chromosome 3 open reading frame 34), also known as MGC14126, is a 163 amino acid protein encoded by a gene that maps to human chromosome 3q29. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.
Image Unavailable-CA1.01544.9026

L-Arginine hydrochloride 98.5-101.0% (by perchloric acid titration), EMPROVE® EXPERT Ph. Eur., BP, JP, USP suitable for use as excipient, SAFC®

Supplier: EMD MILLIPORE – PCS CA EXCEP
Description: L-Arginine monohydrochloride, Cas number: 1119-34-2, Synonyms: a-Amino-d-guanidino valerianic acid hydrochloride, alpha-Amino-delta-guanidino valerianic acid hydrochloride, Arg, suitable for use as excipient EMPROVE* exp Ph Eur,BP,USP, 1 kg

SDS Certificates

Image Unavailable-10488-692

Anti-F9 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10488-692)
Supplier: Bioss
Description: Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (prothrombin, and factors X, IX, V, and VIII), which are involved in a blood coagulation cascade that leads to the formation of insoluble fibrin clots and the promotion of platelet aggregation (1-3). Coagulation factor IX (plasma thromboplastic component, F9, F.IX, HEMB) is a vitamin K-dependent, single chain serine protease that is synthesized in the liver and circulates as an inactive precursor (3,4). Factor XIa mediated proteolytic cleavage of factor IX generates factor IXa, an active serine protease composed of a 145 amino acid light chain and a 236 amino acid catalytic heavy chain, linked through disulfide bonds (5). Genetic alterations at the Factor IX locus such as point mutations, insertions and deletions, can lead to hemophilia B, also known as Christmas disease (6).
Image Unavailable-10165-842

Anti-NDUFS3 Rabbit Polyclonal Antibody

Catalog Number: (10165-842)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to NDUFS3 (NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase))
Image Unavailable-10496-388

Anti-EDRF1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10496-388)
Supplier: Bioss
Description: The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to 16 tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity. EDRF1 (erythroid differentiation-related factor 1), also known as C10orf137 (chromosome 10 open reading frame 137), is a 1,238 amino acid protein containing two TPR repeats. Localizing to nucleus, EDRF1 is involved in transcriptional activation of globin genes by regulating DNA-binding activity of GATA-1 transcription factor. EDRF1 may also play an important role in organ development and histological differentiation. EDRF1 exists as four alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 10q26.13.
Image Unavailable-H-6746.0005BA

Human Acetyl-Tetracosactide (2-24) Trifluoroacetate

Supplier: Bachem Americas
Description: Please see also α-MSH (corresponds to acetyl-ACTH (1-13) amide, H-1075), α-MSH (free acid) (acetyl-ACTH (1-13), H-1070), and (Des-acetyl)-α-MSH (H-4390). Wied: Pituitary Adrenal System Hormones and Behaviour. Symposium on Developments in Endocrinology (1976) / Anon.: ACTH and Related Peptides: Structure, Regulation, and Action. Ann. N.Y. Acad. Sci. 297, 1 (1977) / A.V.Schally: Aspects of Hypothalamic Regulation of the Pituitary Gland. Science 202, 18 (1978) / R.Schwyzer: Studies on Polypeptide Receptors. A Critical View on the Mechanism of ACTH Action. Bull. Schweiz. Acad. Med. Wiss. 34, 263 (1978).

Product Image-10081-626

Anti-MEPE Rabbit Polyclonal Antibody

Catalog Number: (10081-626)
Supplier: Proteintech
Description: Matrix extracellular phosphoglycoprotein (MEPE), also known as osteoblast/osteocyte factor 45 (OF45), is amember of the small integrin-binding ligand N-linked glycopro-tein (SIBLING) family . MEPE promotes renal phosphate excretion and modulates mineralization . It can be phosphorylated by secreted protein kinases. . MEPE is expressed in osteoblasts, osteocytes and odontoblasts, and the expression has also been reported in numerous human tumor cell lines . It is a 525-amino acid protein with a calculated molecular weight of 58 kDa. This antibody raised against a synthetic peptide (CTHGRKYHYVPHRQNNSTR) detects a major band (43 kDa) and two minor bands (98 kDa and 34 kDa).
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(+)-Catechin hydrate ≥95% (by NMR), off-white powder

Supplier: MP Biomedicals
Description: Specific histidine decarboxylase inhibitor. Anti-inflammatory. COX-1 inhibitor. Antioxidant flavonoid. Free radical scavenger. Inhibits lipid peroxidation. Antimetastatic and anticancer compound. Antiangiogenic. Anti-osteoporotic. Antibacterial and antifungal. Neuroprotective. Mono oxidase B inhibitor. Apoptosis and cell cycle arrest inducer. JNK phosphorylation inhibitor. Antispasmodic. Insulin-mimetic.

Image Unavailable-10496-380

Anti-EDRF1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10496-380)
Supplier: Bioss
Description: The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to 16 tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity. EDRF1 (erythroid differentiation-related factor 1), also known as C10orf137 (chromosome 10 open reading frame 137), is a 1,238 amino acid protein containing two TPR repeats. Localizing to nucleus, EDRF1 is involved in transcriptional activation of globin genes by regulating DNA-binding activity of GATA-1 transcription factor. EDRF1 may also play an important role in organ development and histological differentiation. EDRF1 exists as four alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 10q26.13.
Product Image-MSPP-780761006

Human Recombinant IFN-alpha 2A

Catalog Number: (MSPP-780761006)
Supplier: STEMCELL Technologies
Description: Interferon-alpha (IFN-α) is a type I interferon, produced by virus-infected cells, and is released as a soluble factor to initiate antiviral responses (Isaacs and Lindenmann). IFN-α2 is the most potent IFN-α used in fundamental research and in most clinical applications. The best-known IFN-α2 subvariants, 2A and 2B, differ by only one or two amino acids at positions 23 and/or 34 of the mature protein (von Gabain <i>et al.</i>). Type I IFNs exert potent antitumor activity by increasing the cytotoxic activity of NK and T cells, as well as by inhibiting the proliferation of cancer cells (Paul <i>et al.</i>). Additionally, it has been shown that proinflammatory IFN-α modulates the function of B cells in patients with systemic lupus erythematosus (Chang <i>et al.</i>), and pegylated forms of IFN-alpha 2A and 2B have implications in the treatment of hepatitis C (Foster <i>et al.</i>).

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Product Image-10082-508

Anti-ADAT2 Rabbit Polyclonal Antibody

Catalog Number: (10082-508)
Supplier: Proteintech
Description: ADAT2(tRNA-specific adenosine deaminase 2) is also named as DEADC1 and Belongs to the cytidine and deoxycytidylate deaminase family. It is a 24-kDa molecular mass protein that harbors all the conserved motifs required for deamination. ADAT2 and ADAT3 can function as a heterodimer which catalyses inosine formation at the wobble position (position 34) in eukaryotic tRNAs. It has 2 isoforms produced by alternative splicing.
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Cytidine-5'-monophosphate disodium salt hydrate ≥99.0% (by HPLC)

Supplier: TCI America
Description: CAS Number: 6757-06-8
MDL Number: MFCD00064355
Molecular Formula: C9H14N3O8P
Molecular Weight: 367.16
Purity/Analysis Method: >99.0% (HPLC)
Form: Crystal
Specific rotation [a]20/D: 8 deg (C=2, H2O)
Storage Temperature: 0-10°C

SDS Certificates

Product Image-10093-812

Anti-RNF34 Rabbit Polyclonal Antibody

Catalog Number: (10093-812)
Supplier: Proteintech
Description: RNF34(ring finger protein 34) has E3 ubiquitin-protein ligase activity and regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradationis.It is preferentially expressed in esophageal, gastric, and colorectal cancers, suggesting a possible association between RNF34 and the development of digestive tract cancers.Western blot results show the MW of 42-46kd,60kd,130kd.
Image Unavailable-76303-834

Human Recombinant Oncostatin M (from HEK293 Cells)

Supplier: Peprotech
Description: Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptors in hepatoma cells. OSM shares several structural and functional characteristics with LIF, IL-6, and CNTF. Human OSM is active on murine cells. The human OSM gene encodes for a 252 amino acid polypeptide, containing 25 amino acid signal sequence for secretion and a 227 precursor protein. Proteolytic processing of this precursor removes an 18 amino acid C-terminal peptide, and generates the mature OSM form. PeproTech's Recombinant Human Oncostatin M (196 a.a.) is a HEK293 cell-derived, 196 amino-acid length glycoprotein that has a calculated theoretical molecular weight of 22.2 kDa, but migrates at an apparent molecular weight of 32-34 kDa by SDS-PAGE analysis under reducing conditions due to glycosylation.

Product Image-28498-332

Spectra Mesh® Woven Membrane Filters, Spectrum® Laboratories

Supplier: Spectrum Laboratories
Description: Woven filters are constructed of individual strands woven into a mesh screen, and are characterized by precise mesh openings, percent open area, and mesh thickness.

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