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Product Image-77393-388

PureCube Epoxy Activated Agarose XL

Supplier: CUBE BIOTECH
Description: PureCube epoxy agarose XL resin is your best option to couple biomolecules that carry thiol (SH) groups.

Image Unavailable-77440-244

Anti-MGLUR1A/Metabotropic Glutamate Receptor 1a Rabbit Polyclonal Antibody

Catalog Number: (77440-244)
Supplier: Bioss
Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternative splice variants of the GRM1 gene have been described but their full-length nature has not been determined.
Product Image-10398-334

Anti-NR2C2 Rabbit Polyclonal Antibody

Catalog Number: (10398-334)
Supplier: Bioss
Description: Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Plays a fundamental role in early embryonic development and embryonic stem cells. Required for normal spermatogenesis and cerebellum development. Appears to be important for neurodevelopmentally regulated behavior (By similarity). Activates transcriptional activity of LHCG. Antagonist of PPARA-mediated transactivation.
Image Unavailable-CAPIPA5-18203

Anti-FANCG Goat Polyclonal Antibody

Catalog Number: (CAPIPA5-18203)
Supplier: Thermo Scientific
Description: This antibody is predicted to react with canine and porcine based on sequence homology. The Fanconi anemia complementation group currently includes FANCA, FANCB, FANCC, FANCD1 , FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ , FANCL, FANCM and FANCN . The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G.
Image Unavailable-10331-112

Anti-PXR Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10331-112)
Supplier: Bioss
Description: Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the antibiotic rifampicin and various plant metabolites, such as hyperforin, guggulipid, colupulone, and isoflavones. Response to specific ligands is species-specific. Activated by naturally occurring steroids, such as pregnenolone and progesterone. Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes.
Image Unavailable-CAPIPA5-13361

Anti-GRM5 Rabbit Polyclonal Antibody

Catalog Number: (CAPIPA5-13361)
Supplier: Thermo Scientific
Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 (also known as GPRC1E) and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The activity of GRM5 is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current.
Image Unavailable-89285-522

Anti-CD147 Rabbit Monoclonal Antibody (Biotin) [clone: MEM-M6/1]

Catalog Number: (89285-522)
Supplier: Genetex
Description: Monoclonal Antibody [MEM-M6/1] to CD147 (Biotin)
Image Unavailable-76120-990

Anti-PAFAHG Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76120-990)
Supplier: Bioss
Description: Inactivates paf by removing the acetyl group at the sn-2 position. This is a catalytic subunit. Plays an important role during the development of brain.
Image Unavailable-CA82022-814

Sulfo-SMCC (3-Sulfo-N-succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate sodium salt)

Catalog Number: (CA82022-814)
Supplier: G-Biosciences
Description: Ideal for enzyme-antibody crosslinking.
Image Unavailable-89298-756

Anti-CD147 Mouse Monoclonal Antibody [clone: MEM-M6/1]

Catalog Number: (89298-756)
Supplier: Genetex
Description: PE-conjugated Mouse Monoclonal antibody [MEM-M6/1] to CD147
Image Unavailable-89298-754

Anti-CD147 Mouse Monoclonal Antibody [clone: MEM-M6/1]

Catalog Number: (89298-754)
Supplier: Genetex
Description: APC-conjugated Mouse Monoclonal antibody [MEM-M6/1] to CD147
Product Image-470045-014

Science Take-Out® Testing For Genetic Disorders That Cause Brain Damage

Supplier: SCIENCE TAKE-OUT, LLC
Description: Follow The Case Of Twins Who Have Newborn Screening For Genetic Disorders.

Product Image-470315-142

Stem Investigations: Design a Water Filter

Catalog Number: (470315-142)
Supplier: Ward's Science
Description: How is the water that comes out of our faucets made safe for consumption?
Image Unavailable-89288-546

Anti-NR3C2 Rabbit Polyclonal Antibody

Catalog Number: (89288-546)
Supplier: Genetex
Description: Rabbit polyclonal antibody to Mineralocorticoid Receptor
Product Image-89348-828

Anti-NR3C1 Rabbit Polyclonal Antibody

Catalog Number: (89348-828)
Supplier: Genetex
Description: The protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined. [provided by RefSeq]
Product Image-77393-206

PureCube Amine Activated MagBeads

Supplier: CUBE BIOTECH
Description: PureCube amine activated MagBeads are your best option to couple biomolecules that carry free-standing carboxy (COOH) groups.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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