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Image Unavailable-10459-684

Anti-SDCCAG8 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10459-684)
Supplier: Bioss
Description: The exact function of SDCCAG8 remains unknown. It is expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors.
Image Unavailable-77436-736

Anti-NALP6 Rabbit Polyclonal Antibody

Catalog Number: (77436-736)
Supplier: Bioss
Description: May contribute to arginine-vasopressin (AVP)-mediated regulation of renal salt-water balance, glucose and lipid metabolism, apoptosis, and/or cell cycle. Binds arginine-vasopressin but not angiotensin II and acts as an arginine-vasopressin V2 receptor. Plays a role in modulating inflammatory responses in the colon to allow recovery from intestinal epithelial damage and limit tumorigenic potential. Protects against the development of colitis by controlling the composition of the gut microbiota by preventing colonization of the colon by harmful, inflammation-inducing bacteria such as Prevotella species. May mediate activation of CASP1 via ASC, promote activation of NF-kappa-B and stimulate cAMP accumulation (By similarity).
Image Unavailable-75920-320

Anti-KRT7 Mouse Monoclonal Antibody [clone: KRT7/903]

Catalog Number: (75920-320)
Supplier: Biotium
Description: Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. Antibody to cytokeratin is useful in distinguishing ovarian carcinomas (keratin 7 ) from colon carcinomas (keratin 7-).
Image Unavailable-89310-386

Anti-NOTCH4 Rabbit Polyclonal Antibody

Catalog Number: (89310-386)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to st14 (suppression of tumorigenicity 14 (colon carcinoma))
Product Image-10093-656

Anti-RhoGDI Rabbit Polyclonal Antibody

Catalog Number: (10093-656)
Supplier: Proteintech
Description: Aplysia Ras-related homologs (ARHs), also called Rho genes, belong to the RAS gene superfamily encoding small guanine nucleotide exchange (GTP/GDP) factors. The ARH proteins may be kept in the inactive, GDP-bound state by interaction with GDP dissociation inhibitors, such as ARHGDIA (also called Rho GDP-dissociation inhibitor 1, Rho GDI1). Rho GDI1 acts as a metastasis-related protein in colon and prostate cancer patients and may be useful as a diagnostic biomarker to prevent colon and prostate cancer metastasis.
Image Unavailable-10081-924

Anti-ALDH1B1 Rabbit Polyclonal Antibody

Catalog Number: (10081-924)
Supplier: Proteintech
Description: Aldehyde dehydrogenases (ALDHs) belong to a superfamily of NAD(P)+-dependent enzymes, which catalyze the oxidation of endogenous and exogenous aldehydes to their corresponding acids. ALDH1B1 is a mitochondrial ALDH that it is dramatically upregulated in human colonic adenocarcinoma, making it a potential biomarker for human colon cancer.. ALDH1B1 is a homotetramer expressed in various adult and fetal human tissues including liver, testis, kidney, skeletal muscle, heart, placenta, brain and lung. This antibody is specific to ALDH1B1.
Image Unavailable-75920-318

Anti-KRT7 Mouse Monoclonal Antibody (CF640R) [clone: KRT7/903]

Supplier: Biotium
Description: Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. Antibody to cytokeratin is useful in distinguishing ovarian carcinomas (keratin 7 ) from colon carcinomas (keratin 7-).

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.

Image Unavailable-10430-122

Anti-PDGFRL Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10430-122)
Supplier: Bioss
Description: This protein is expressed in colon, lung and liver. Defects in PDGFRL are associated with colorectal cancer.
Image Unavailable-89366-220

Anti-URP1 Rabbit Polyclonal Antibody

Catalog Number: (89366-220)
Supplier: Genetex
Description: Due to a concerted effort to identify biomarkers for lung and colon carcinomas by genome-wide transcriptional profiling, the identification and cloning of one such gene as well as two additional closely related genes was achieved. Due to the strong sequence homology to the C. elegans UNC-112 a novel gene gene was named URP1, for UNC-112 related protein. Another novel related gene, URP2 and the previously discovered MIG-2 gene was also identified. Transcriptional analysis shows that only URP1 is significantly differentially regulated, being over-expressed in 70% of the colon carcinomas and 60% of the lung carcinomas tested. Quantification of URP1 expression by qRT-PCR showed up-regulation of the gene by 60-fold in lung tumors and up to nearly 6-fold in colon tumors. Northern blot analysis of URP1 indicates that normal expression is restricted to neuromuscular tissues. In contrast, the expression of URP2 appears to be confined primarily to tissues of the immune system. URP1 has the potential to be one of the most important prognostic and diagnostic markers of colon or lung cancer.
Product Image-10087-250

Anti-GLRX3 Rabbit Polyclonal Antibody

Catalog Number: (10087-250)
Supplier: Proteintech
Description: GLRX3(Glutaredoxin-3) is also named as PICOT, TXNL2. Mammalian glutaredoxin 3 is an essential protein involved in the regulation of signal transduction, for instance during immune cell activation and development of cardiac hypertrophy, presumably in response to redox signals. Glrx3 could take a pivotal role in colon and lung cancer cells during the tumorigenesis, which is expressed in lung and colon cancers consistently and preferentially.
Product Image-10081-922

Anti-ALDH1B1 Rabbit Polyclonal Antibody

Catalog Number: (10081-922)
Supplier: Proteintech
Description: Aldehyde dehydrogenases (ALDHs) belong to a superfamily of NAD(P)+-dependent enzymes, which catalyze the oxidation of endogenous and exogenous aldehydes to their corresponding acids. ALDH1B1 is a mitochondrial ALDH that it is dramatically upregulated in human colonic adenocarcinoma, making it a potential biomarker for human colon cancer.. ALDH1B1 is a homotetramer expressed in various adult and fetal human tissues including liver, testis, kidney, skeletal muscle, heart, placenta, brain and lung.
Product Image-76548-722

Forceps, Bayonet, Mortech

Catalog Number: (76548-722)
Supplier: Mortech Manufacturing
Description: Ergonomically designed for a more comfortable wrist position during post-mortem dissections. Offers speculum function for hollow cavity specimens such as uterus, bladder and colon.
Image Unavailable-75789-982

Human Recombinant 15-PGDH (from Cells)

Catalog Number: (75789-982)
Supplier: Prosci
Description: 15-hydroxyprostaglandin dehydrogenase [NAD(+)], also known as Prostaglandin dehydrogenase 1, 15-PGDH, HPGD and PGDH1, belongs to the short-chain dehydrogenases/reductases (SDR) family. HPGD localizes to the cytoplasm and can be found in colon epithelium, existing as a homodimer. HPGD catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. HPGD is down-regulated by cortisol, dexamethasone and betamethasone, up-regulated by TGFB1. HPGD inhibits in vivo proliferation of colon cancer cells. HPGD is the key enzyme for the inactivation of prostaglandins, and thus regulates processes such as inflammation or proliferation.
Image Unavailable-75789-016

Human Recombinant 40S Ribosomal S19 (from E. coli)

Catalog Number: (75789-016)
Supplier: Prosci
Description: 40S Ribosomal Protein S19 (RPS19) is a ribosomal protein that Belongs to the ribosomal protein S19e family. RPS19 is located in the nucleoli, and higher level expression is seen in colon carcinoma tissue than normal colon tissue. It required for pre-rRNA processing and maturation of 40S ribosomal subunits. RPS19 plays a role in many biological processes, such as endocrine pancreas development, erythrocyte differentiation, mRNA metabolic process. Defects in RPS19 are the cause of Diamond-Blackfan anemia type 1 (DBA1), which is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy.
Image Unavailable-10166-438

Anti-MLH1 Rabbit Polyclonal Antibody

Catalog Number: (10166-438)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to MLH1 (mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli))
Product Image-10750-542

Anti-MACC1 Rabbit Polyclonal Antibody

Catalog Number: (10750-542)
Supplier: Prosci
Description: MACC1 Antibody: Metastasis associated in colon cancer 1 (MACC1) is a key regulator of the hepatocyte growth factor (HGF)-HGF receptor (MET) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. MACC1 protein consists of four domains: ZU5, SH3, and two C-terminal death domains (DD). Expression of MACC1 was found significantly upregulated in malignant tissues (colon cancer of all stages as well as liver and lung metastases) compared to normal tissues or adenomas. MACC1 represents an early and crucial prognostic indicator for colon cancer metastasis that is independent of age, sex, tumor infiltration, nodal status, and lymph vessel invasion. Besides its involvement in signal transduction with the MET receptor, MACC1 also links MET signaling and apoptosis. MACC1 may also be an important therapeutic target for colorectal cancer treatment.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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