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Catalog Number: (TCD0612-5G)
Supplier: TCI America
Description: CAS Number: 18835-59-1
MDL Number: MFCD00016542
Molecular Formula: C9H9I2NO3
Molecular Weight: 432.98
Purity/Analysis Method: >98.0% (T)
Form: Crystal
Melting point (°C): 213
Specific rotation [a]20/D: 1.2 deg (C=5, 1mol/L HCl)


Supplier: TCI America
Description: CAS Number: 865350-17-0
MDL Number: MFCD09265121
Molecular Formula: C9H15BO2
Molecular Weight: 166.03
Purity/Analysis Method: >95.0% (GC,T)
Form: Clear Liquid
Boiling point (°C): 81
Flash Point (°C): 66
Specific Gravity (20/20): 0.94
Storage Temperature: 0-10°C

SDS

Catalog Number: (RL010-001-B54)
Supplier: Rockland Immunochemical
Description: Mouse IL-27/p28 Subunit, also known as Interleukin-30, is a member of the IL-12 family of cytokines. When combined with EBI3 (Epstein-Barr virus induced gene 3), the heterodimer formed is IL-27. Mouse p28 is a proinflammatory cytokine inducing immunomodulatory effects. Current research is underway to delineate specific biological functions. Recombinant mouse p28 is a single-chain 207 amino acid peptide with a mass of approximately 23,697 Daltons.

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Supplier: Dynalon
Description: These cylinders feature permanently easy to read blue screened graduations that resist fading and scratching after repeated autoclaving. Meets stringent international quality criteria according to ISO 6706 standards. Tolerances according to DIN 12 680 TT, Class B. Maximum temperature: PP 121°C, PMP 135°C.

Catalog Number: (10459-158)
Supplier: Bioss
Description: C12orf23 (chromosome 12 open reading frame 23), also known as FLJ11721, FLJ13959 or MGC17943, is a 116 amino acid multi-pass membrane protein belonging to the UPF0444 family. C12orf23 is encoded by a gene located on human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a number of skeletal deformities, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy.


Supplier: TCI America
Description: CAS Number: 122-46-3
MDL Number: MFCD00041910
Molecular Formula: C9H10O2
Molecular Weight: 150.18
Purity/Analysis Method: >99.0% (GC)
Form: Clear Liquid
Boiling point (°C): 212
Melting point (°C): 12
Flash Point (°C): 95
Specific Gravity (20/20): 1.05
Catalog Number: (10749-562)
Supplier: Prosci
Description: Caspase-12 Antibody: (Small)Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the main, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues.


Catalog Number: (10477-526)
Supplier: Bioss
Description: The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC38 (coiled-coil domain containing 38) is a 563 amino acid protein encoded by a gene that maps to human chromosome 12q23.1. Encoding over 1,100 genes, chromosome 12 comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.


Supplier: BURKLE INC
Description: Delivery tubes made of PP are resistant against weak acids, caustic solutions and detergents.
Delivery tubes made of PVDF are especially for acids and caustic solutions; not for strongly oxidizing acids and caustic solutions.
Delivery tubes made of stainless steel 304 are for solvents and liquids of VbF Hazard Class AIII (not easily flammable).
Battery pump for safe filling of car batteries with acid or distilled water.

Supplier: Peprotech
Description: TIMP-2 is an extracellular inhibitor of MMPs, including MMP-1, -2, -3, -7, -8, -9, -10, -12, -13, -14, -15, -16 and -19. It belongs to the I35 (TIMP) family of irreversible protease inhibitors that function as key modulators of extracellular matrix degradation during tissue development and remodeling. TIMP-2 can also act through a MMP-independent mechanism inhibiting endothelial cell proliferation in vitro and demonstrates anti-angiogenic activities Recombinant Human TIMP-2 is a 21.8 kDa protein containing 194 amino acid residues.

Catalog Number: (CA16777-056)
Supplier: Cytiva
Description: HyClone™ DMEM/F12 is an equal parts blend of DMEM and Ham’s F12 media that is widely used for culturing many different mammalian cells including MDCK, Glial cells, fibroblasts, and endothelial cells. This formulation combines the high concentration of glucose, amino acids and vitamins from DMEM with the wide variety of other components available in Ham’s F-12.


Catalog Number: (77661-208)
Supplier: FUJIFILM IRVINE SCIENTIFIC, INC
Description: Cytokines for polarizing T cells into T regulatory cells. T regulatory cells (Tregs) are a subset of T cells that suppress immune function. They are characterized by the expression of CD4, CD25 and Foxp3 and are known to produce immunosuppressive cytokines TGF-β 1 and IL-10. Tregs can be cultured from naive CD4+ T cells by culturing them in the presence of IL-2 and TGF-β 1 with CD3 and CD28 stimulation. In some cases cells are also cultured with neutralizing antibodies to IL-4, IFNγ and IL-12 and/or retinoic acid.

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Catalog Number: (10477-522)
Supplier: Bioss
Description: The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC38 (coiled-coil domain containing 38) is a 563 amino acid protein encoded by a gene that maps to human chromosome 12q23.1. Encoding over 1,100 genes, chromosome 12 comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.


Catalog Number: (89415-438)
Supplier: Prosci
Description: Caspase-12 Antibody: Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the mains, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues.


Catalog Number: (10749-410)
Supplier: Prosci
Description: Caspase-12 Antibody: Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the mains, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta.


Catalog Number: (76107-224)
Supplier: Bioss
Description: The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC38 (coiled-coil domain containing 38) is a 563 amino acid protein encoded by a gene that maps to human chromosome 12q23.1. Encoding over 1,100 genes, chromosome 12 comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.


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