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Anti-TAS1R1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10663-962)
Supplier: Bioss
Description: Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.
Image Unavailable-10663-960

Anti-TAS1R1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10663-960)
Supplier: Bioss
Description: Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.
Product Image-10813-936

Anti-GRIN1 Rabbit Polyclonal Antibody

Catalog Number: (10813-936)
Supplier: Prosci
Description: NMDA receptors are members of the ionotropic class of glutamate receptors, which also includes Kainate and AMPA receptors. NMDA receptors consist of NR1 subunits combined with one or more NR2 (A-D) or NR3 (A-B) subunits. The ligand-gated channel is permeable to cations including Ca2+, and at resting membrane potentials NMDA receptors are inactive due to a voltage-dependent blockade of the channel pore by Mg2+. NMDA receptor activation, which requires binding of glutamate and glycine, leads to an influx of Ca2+ into the postsynaptic region where it activates several signaling cascades, including pathways leading to the induction of long-term potentiation (LTP) and depression (LTD). NMDA receptors have a critical role in excitatory synaptic transmission and plasticity in the CNS. They govern a range of physiological conditions including neurological disorders caused by excitotoxic neuronal injury, psychiatric disorders and neuropathic pain syndromes.
Product Image-10813-862

Anti-GRIN1 Rabbit Polyclonal Antibody

Catalog Number: (10813-862)
Supplier: Prosci
Description: NMDA receptors are members of the ionotropic class of glutamate receptors, which also includes Kainate and AMPA receptors. NMDA receptors consist of NR1 subunits combined with one or more NR2 (A-D) or NR3 (A-B) subunits. The ligand-gated channel is permeable to cations including Ca2+, and at resting membrane potentials NMDA receptors are inactive due to a voltage-dependent blockade of the channel pore by Mg2+. NMDA receptor activation, which requires binding of glutamate and glycine, leads to an influx of Ca2+ into the postsynaptic region where it activates several signaling cascades, including pathways leading to the induction of long-term potentiation (LTP) and depression (LTD). NMDA receptors have a critical role in excitatory synaptic transmission and plasticity in the CNS. They govern a range of physiological conditions including neurological disorders caused by excitotoxic neuronal injury, psychiatric disorders and neuropathic pain syndromes.
Product Image-10099-674

Anti-EIF2D Rabbit Polyclonal Antibody

Catalog Number: (10099-674)
Supplier: Prosci
Description: LGTN is a protein receptor that localizes phosphoglycoproteins within endosomes and at the cell periphery. This trafficking receptor for phosphoglycoproteins may play a role in neuroplasticity by modulating cell-cell interactions, intracellular adhesion, and protein binding at membrane surfaces. In hippocampal neurons, long-lasting down-regulation of ligatin mRNA levels occurs via post-transcriptional RNA processing following glutamate receptor activation. This protein contains single PUA and SUI1 domains and these domains may function in RNA binding and translation initiation, respectively.This gene encodes a protein receptor that localizes phosphoglycoproteins within endosomes and at the cell periphery. This trafficking receptor for phosphoglycoproteins may play a role in neuroplasticity by modulating cell-cell interactions, intracellular adhesion, and protein binding at membrane surfaces. In hippocampal neurons, long-lasting down-regulation of ligatin mRNA levels occurs via post-transcriptional RNA processing following glutamate receptor activation. This protein contains single PUA and SUI1 domains and these domains may function in RNA binding and translation initiation, respectively.
Image Unavailable-76082-226

Anti-NMDAR2A Tyr1325 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76082-226)
Supplier: Bioss
Description: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Image Unavailable-76116-326

Anti-CHRNA3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76116-326)
Supplier: Bioss
Description: Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters. Two important members of this family are the nicotinic acetylcholine and glutamate receptors, both of which are composed of five homologous subunits forming a transmembrane aqueous pore. These transmembrane receptors change conformation in response to their cognate neurotransmitter. Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing ions to move through the pore. Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system. The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, an enzyme that rapidly hydrolyzes acetylcholine. AChR?, also known as LNCR2, PAOD2, NACHRA3 or CHRNA3, is a 505 amino acid multi-pass membrane protein that belongs to the ligand-gated ion channel receptor family and may play a role in neurotransmission.
Image Unavailable-76116-328

Anti-CHRNA3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76116-328)
Supplier: Bioss
Description: Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters. Two important members of this family are the nicotinic acetylcholine and glutamate receptors, both of which are composed of five homologous subunits forming a transmembrane aqueous pore. These transmembrane receptors change conformation in response to their cognate neurotransmitter. Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing ions to move through the pore. Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system. The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, an enzyme that rapidly hydrolyzes acetylcholine. AChR?, also known as LNCR2, PAOD2, NACHRA3 or CHRNA3, is a 505 amino acid multi-pass membrane protein that belongs to the ligand-gated ion channel receptor family and may play a role in neurotransmission.
Product Image-10111-178

Anti-GRIA2 Rabbit Polyclonal Antibody

Catalog Number: (10111-178)
Supplier: Prosci
Description: GRIA2 is one of the glutamate receptors, which are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with mul
Image Unavailable-TCC2235-5G

Folinic acid calcium salt, hydrate ≥98.0% (by HPLC, titration analysis)

Supplier: TCI America
Description: CAS Number: 1492-18-8 MDL Number: MFCD00006704 Molecular Formula: C20H23N7O7 Molecular Weight: 511.51 Purity/Analysis Method: <gt/>98.0% (HPLC,T) Form: Crystal

SDS Certificates

Image Unavailable-CA10816-812

Anti-GRIA1 Mouse Monoclonal Antibody [clone: N355/1]

Catalog Number: (CA10816-812)
Supplier: Biolegend
Description: GluR1 Monoclonal Antibody, Clone: N355/1, Host: Mouse, Isotype: IgG1, Reactivity: Mouse, Rat, Immunogen: against a fusion protein corresponding to amino acids 1-389 of rat GluA1/GluR1 glutamate receptor, Conjugate: purified, Application: WB, IHC, Size: 100 ul
Image Unavailable-10663-958

Anti-TAS1R1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10663-958)
Supplier: Bioss
Description: Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.
Image Unavailable-10663-968

Anti-TAS1R1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10663-968)
Supplier: Bioss
Description: Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.
Image Unavailable-CA10816-656

Anti-GRIA2 Mouse Monoclonal Antibody [clone: L21/32]

Catalog Number: (CA10816-656)
Supplier: Biolegend
Description: GluR2 Monoclonal Antibody, clone: L21/32, Host: Mouse, Reactivity: Human, Rat, Mouse, Isotype: IgG1, Immunogen: a fusion protein corresponding to amino acids 834-883 of rat GluA2/GluR2 glutamate receptor, synonyms: GluA2/GluR2, Application: IHC, size: 100 ul
Image Unavailable-10494-500

Anti-VGLUT2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10494-500)
Supplier: Bioss
Description: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.
Product Image-10087-570

Anti-GLAST Rabbit Polyclonal Antibody

Catalog Number: (10087-570)
Supplier: Proteintech
Description: SLC1A3, also known as EAAT-1 or GLAST, is a membrane-bound protein localized in glial cells and pre-synaptic glutamatergic nerve endings. It transports the excitatory neurotransmitters L-glutamate and D-aspartate, which is essential for terminating the postsynaptic acction of glutamate. Recently, a correlation between expression/function of glial EAAT-1 and tumor proliferation has been reported. The exceptionally rare expression of EAAT-1 in non-neoplastic choroid plexus (CP) compared to choroid plexus tumors (CPT) may distinguishes neoplastic from normal CP. There are a number of splicing variants of SLC1A3, like GLAST1a and GLAST1b, exist due to the exon skipping. It also undergo glycosylation. Variety of bands can be observed in the western blotting assay: 50-55 kDa represents the unglycosylated GLAST1a or GLAST1b, 65-70 kDa correspond to the glycosylated proteins, larger proteins between 90-130 kDa may be the multimers of SLC1A3. (11086157, 17471058, 12546822)
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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