Anti-Calretinin (H-5) Mouse Monoclonal Antibody [clone: H-5]

Supplier: Diagnostic Biosystems

MOB593-05-RUO MOB593-RUO MOB593-01-RUO

CA76634-236EA 507.61 CAD

CA76634-236 CA76634-238 CA76634-234

Anti-Calretinin (H-5) Mouse Monoclonal Antibody [clone: H-5]

Antibodies

Calbindin D28K and Calretinin (also designated CR or 29 kDa Calbindin) are two closely related intracellular calcium-binding proteins belonging to the Troponin-C superfamily. Initially isolated from chick retina. Calretinin is an intracellular calcium-binding protein belonging to the troponin C superfamily characterized by a structural motif described as the EF-hand domain. The immunohistochemical detection of calretinin in developing cerebellum is restricted to the later stages indicated by weak staining from week 21 of gestation in Purkinje and basket cells and in neurons of the dentate nucleus. The intensity of staining increases as the cerebellum matures. In tumors, calretinin has been detected in mesotheliomas and some pulmonary adenocarcinomas.

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