Anti-Adenovirus Mouse Monoclonal Antibody [clone: M58+M73]

Supplier: Diagnostic Biosystems

MOB355-01-RUO MOB355-05-RUO MOB355-RUO

CA76633-746EA 144.79 CAD

CA76633-746 CA76633-748 CA76633-750

Anti-Adenovirus Mouse Monoclonal Antibody [clone: M58+M73]

Antibodies

This antibody reacts with adenovirus. The adenovirus early gene product E1A is a potent stimulator of cellular proliferation, which when overexpressed can overcome the growth-inhibitory effects of TGF-β. The E1A region encodes a series of related proteins (35 to 46 kDa) with multifunctional capabilities and forms a specific complex with the retinoblastoma tumor suppressor gene product. The E1A and E1B regions together comprise the transforming region of adenovirus. While expression of E1A alone is sufficient to immortalize primary cells, complete transformation requires the additional expression of the E1B region.

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