Anti-CD30 Ki-1 Antigen Mouse Monoclonal Antibody [clone: Ber-H2]

Supplier: Diagnostic Biosystems

MOB032-01-RUO MOB032-05-RUO MOB032-RUO

CA76633-116EA 144.79 CAD

CA76633-116 CA76633-118 CA76633-120

Anti-CD30 Ki-1 Antigen Mouse Monoclonal Antibody [clone: Ber-H2]

Antibodies

This antibody recognizes a single chain glycoprotein of 105/120 kDa, identified as CD30/Ki-1. Its epitope is located between aa112-412. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120 kDa glycoprotein. In Hodgkin's disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).

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