Anti-DLK1 Monoclonal Antibody [clone: PF183E]

Supplier: Adipogen

AG-20A-0058Y-C050 AG-20A-0058Y-C100

102971-652EA 324.62 CAD

102971-652 102971-654

Anti-DLK1 Monoclonal Antibody [clone: PF183E]

Antibodies

The transmembrane and secreted protein delta-like 1 homolog (DLK1; Protein delta homolog 1; Preadipocyte factor 1; Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.

Type: Primary
Antigen: DLK1
Clonality: Monoclonal
Clone: PF183E
Conjugation: Unconjugated
Epitope:
Host:
Isotype: Rat IgG2akappa
Reactivity: Mouse

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